# Decentralised, Collaborative, and Privacy-preserving Machine Learning for Multi-Hospital Data

arXiv: https://arxiv.org/abs/2402.00205 · HTML: https://mlsanity.com/paper/2402.00205/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 22 of its 70 references that are in the map.
- First posted on arXiv 31 Jan 2024.

## Builds on (most cited first, 22 of 22)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Communication-Efficient Learning of Deep Networks from Decentralized Data](https://mlsanity.com/paper/1602.05629/) (2016)
- [Densely Connected Convolutional Networks](https://mlsanity.com/paper/1608.06993/) (2016)
- [Deep Learning with Differential Privacy](https://mlsanity.com/paper/1607.00133/) (2016)
- [Membership Inference Attacks against Machine Learning Models](https://mlsanity.com/paper/1610.05820/) (2016)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [A Survey on Deep Learning in Medical Image Analysis](https://mlsanity.com/paper/1702.05747/) (2017)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [Membership Inference Attacks From First Principles](https://mlsanity.com/paper/2112.03570/) (2021)
- [Renyi Differential Privacy](https://mlsanity.com/paper/1702.07476/) (2017)
- [The Future of Digital Health with Federated Learning](https://mlsanity.com/paper/2003.08119/) (2020)
- [Differentially Private Federated Learning: A Client Level Perspective](https://mlsanity.com/paper/1712.07557/) (2017)
- [Opacus: User-Friendly Differential Privacy Library in PyTorch](https://mlsanity.com/paper/2109.12298/) (2021)
- [PadChest: A large chest x-ray image dataset with multi-label annotated reports](https://mlsanity.com/paper/1901.07441/) (2019)
- [Scalable Private Learning with PATE](https://mlsanity.com/paper/1802.08908/) (2018)
- [Unlocking High-Accuracy Differentially Private Image Classification through Scale](https://mlsanity.com/paper/2204.13650/) (2022)
- [R'enyi Differential Privacy of the Sampled Gaussian Mechanism](https://mlsanity.com/paper/1908.10530/) (2019)
- [TorchXRayVision: A library of chest X-ray datasets and models](https://mlsanity.com/paper/2111.00595/) (2021)
- [On the limits of cross-domain generalization in automated X-ray prediction](https://mlsanity.com/paper/2002.02497/) (2020)
- [Learning to recognize Abnormalities in Chest X-Rays with Location-Aware Dense Networks](https://mlsanity.com/paper/1803.04565/) (2018)
- [When Federated Learning Meets Blockchain: A New Distributed Learning Paradigm](https://mlsanity.com/paper/2009.09338/) (2020)
- [Defending against Reconstruction Attacks through Differentially Private Federated Learning for Classification of Heterogeneous Chest X-Ray Data](https://mlsanity.com/paper/2205.03168/) (2022)

## Built on by (most cited first, 5 of 5)

- [MINGLE: Mixture of Null-Space Gated Low-Rank Experts for Test-Time Continual Model Merging](https://mlsanity.com/paper/2505.11883/) (2025)
- [Null-Space Filtering for Data-Free Continual Model Merging: Preserving Stability, Promoting Plasticity](https://mlsanity.com/paper/2509.21413/) (2025)
- [Federated Few-Shot Learning for Epileptic Seizure Detection Under Privacy Constraints](https://mlsanity.com/paper/2512.13717/) (2025)
- [C2FL: Clustered Continual Federated Learning under Spatial and Temporal Drift](https://mlsanity.com/paper/2606.18003/) (2026)
- [On What We Can Learn from Low-Resolution Data](https://mlsanity.com/paper/2605.12168/) (2026)

## Abstract (arXiv)

Machine Learning (ML) has demonstrated its great potential on medical data analysis. Large datasets collected from diverse sources and settings are essential for ML models in healthcare to achieve better accuracy and generalizability. Sharing data across different healthcare institutions is challenging because of complex and varying privacy and regulatory requirements. Hence, it is hard but crucial to allow multiple parties to collaboratively train an ML model leveraging the private datasets available at each party without the need for direct sharing of those datasets or compromising the privacy of the datasets through collaboration. In this paper, we address this challenge by proposing Decentralized, Collaborative, and Privacy-preserving ML for Multi-Hospital Data (DeCaPH). It offers the following key benefits: (1) it allows different parties to collaboratively train an ML model without transferring their private datasets; (2) it safeguards patient privacy by limiting the potential privacy leakage arising from any contents shared across the parties during the training process; and (3) it facilitates the ML model training without relying on a centralized server. We demonstrate the generalizability and power of DeCaPH on three distinct tasks using real-world distributed medical datasets: patient mortality prediction using electronic health records, cell-type classification using single-cell human genomes, and pathology identification using chest radiology images. We demonstrate that the ML models trained with DeCaPH framework have an improved utility-privacy trade-off, showing it enables the models to have good performance while preserving the privacy of the training data points. In addition, the ML models trained with DeCaPH framework in general outperform those trained solely with the private datasets from individual parties, showing that DeCaPH enhances the model generalizability.