# Next Visit Diagnosis Prediction via Medical Code-Centric Multimodal Contrastive EHR Modelling with Hierarchical Regularisation

arXiv: https://arxiv.org/abs/2401.11648 · HTML: https://mlsanity.com/paper/2401.11648/

## Key facts

- Cited by 5 papers in the map (data through 14 Oct 2026).
- Builds on 28 of its 40 references that are in the map.
- First posted on arXiv 22 Jan 2024.

## Builds on (most cited first, 28 of 28)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Representation Learning with Contrastive Predictive Coding](https://mlsanity.com/paper/1807.03748/) (2018)
- [Layer Normalization](https://mlsanity.com/paper/1607.06450/) (2016)
- [Convolutional Neural Networks for Sentence Classification](https://mlsanity.com/paper/1408.5882/) (2014)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [Multimodal Transformer for Unaligned Multimodal Language Sequences](https://mlsanity.com/paper/1906.00295/) (2019)
- [Contrastive Learning of Medical Visual Representations from Paired Images and Text](https://mlsanity.com/paper/2010.00747/) (2020)
- [Tensor Fusion Network for Multimodal Sentiment Analysis](https://mlsanity.com/paper/1707.07250/) (2017)
- [RETAIN: An Interpretable Predictive Model for Healthcare using Reverse Time Attention Mechanism](https://mlsanity.com/paper/1608.05745/) (2016)
- [xDeepFM: Combining Explicit and Implicit Feature Interactions for Recommender Systems](https://mlsanity.com/paper/1803.05170/) (2018)
- [Efficient Low-rank Multimodal Fusion with Modality-Specific Factors](https://mlsanity.com/paper/1806.00064/) (2018)
- [Doctor AI: Predicting Clinical Events via Recurrent Neural Networks](https://mlsanity.com/paper/1511.05942/) (2015)
- [Learning Modality-Specific Representations with Self-Supervised Multi-Task Learning for Multimodal Sentiment Analysis](https://mlsanity.com/paper/2102.04830/) (2021)
- [GRAM: Graph-based Attention Model for Healthcare Representation Learning](https://mlsanity.com/paper/1611.07012/) (2016)
- [Dipole: Diagnosis Prediction in Healthcare via Attention-based Bidirectional Recurrent Neural Networks](https://mlsanity.com/paper/1706.05764/) (2017)
- [Using Clinical Notes with Time Series Data for ICU Management](https://mlsanity.com/paper/1909.09702/) (2019)
- [Collaborative Graph Learning with Auxiliary Text for Temporal Event Prediction in Healthcare](https://mlsanity.com/paper/2105.07542/) (2021)
- [How to Leverage Multimodal EHR Data for Better Medical Predictions?](https://mlsanity.com/paper/2110.15763/) (2021)
- [Characterizing the Value of Information in Medical Notes](https://mlsanity.com/paper/2010.03574/) (2020)
- [On the Importance of Clinical Notes in Multi-modal Learning for EHR Data](https://mlsanity.com/paper/2212.03044/) (2022)
- [MIPO: Mutual Integration of Patient Journey and Medical Ontology for Healthcare Representation Learning](https://mlsanity.com/paper/2107.09288/) (2021)
- [InterMulti:Multi-view Multimodal Interactions with Text-dominated Hierarchical High-order Fusion for Emotion Analysis](https://mlsanity.com/paper/2212.10030/) (2022)

## Built on by (most cited first, 5 of 5)

- [Global Contrastive Training for Multimodal Electronic Health Records with Language Supervision](https://mlsanity.com/paper/2404.06723/) (2024)
- [Overcoming Uncertain Incompleteness for Robust Multimodal Sequential Diagnosis Prediction via Curriculum Data Erasing Guided Knowledge Distillation](https://mlsanity.com/paper/2407.19540/) (2024)
- [RuCCoD: Towards Automated ICD Coding in Russian](https://mlsanity.com/paper/2502.21263/) (2025)
- [Mitigating Stethoscope-Induced Shortcuts in Respiratory Sound Classification under Federated Domain Generalization with Causality-Inspired Interventions](https://mlsanity.com/paper/2605.29862/) (2026)
- [HyperANFIS: Enhancing Rule Representation and Interpretability in Adaptive Neuro-Fuzzy Systems via Hyperbolic Geometry](https://mlsanity.com/paper/2608.11768/) (2026)

## Abstract (arXiv)

Predicting next visit diagnosis using Electronic Health Records (EHR) is an essential task in healthcare, critical for devising proactive future plans for both healthcare providers and patients. Nonetheless, many preceding studies have not sufficiently addressed the heterogeneous and hierarchical characteristics inherent in EHR data, inevitably leading to sub-optimal performance. To this end, we propose NECHO, a novel medical code-centric multimodal contrastive EHR learning framework with hierarchical regularisation. First, we integrate multifaceted information encompassing medical codes, demographics, and clinical notes using a tailored network design and a pair of bimodal contrastive losses, all of which pivot around a medical codes representation. We also regularise modality-specific encoders using a parental level information in medical ontology to learn hierarchical structure of EHR data. A series of experiments on MIMIC-III data demonstrates effectiveness of our approach.
