# Fusing Echocardiography Images and Medical Records for Continuous Patient Stratification

arXiv: https://arxiv.org/abs/2401.07796 · HTML: https://mlsanity.com/paper/2401.07796/

## Key facts

- Cited by 3 papers in the map (data through 14 Oct 2026).
- Builds on 24 of its 46 references that are in the map.
- First posted on arXiv 15 Jan 2024.

## Builds on (most cited first, 24 of 24)

- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Multimodal Machine Learning: A Survey and Taxonomy](https://mlsanity.com/paper/1705.09406/) (2017)
- [Revisiting Deep Learning Models for Tabular Data](https://mlsanity.com/paper/2106.11959/) (2021)
- [Transformers in Time Series: A Survey](https://mlsanity.com/paper/2202.07125/) (2022)
- [Multimodal Learning with Transformers: A Survey](https://mlsanity.com/paper/2206.06488/) (2022)
- [Attention Bottlenecks for Multimodal Fusion](https://mlsanity.com/paper/2107.00135/) (2021)
- [Escaping the Big Data Paradigm with Compact Transformers](https://mlsanity.com/paper/2104.05704/) (2021)
- [Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiography](https://mlsanity.com/paper/1908.06948/) (2019)
- [Hidden Stratification Causes Clinically Meaningful Failures in Machine Learning for Medical Imaging](https://mlsanity.com/paper/1909.12475/) (2019)
- [Understanding How Dimension Reduction Tools Work: An Empirical Approach to Deciphering t-SNE, UMAP, TriMAP, and PaCMAP for Data Visualization](https://mlsanity.com/paper/2012.04456/) (2020)
- [SCARF: Self-Supervised Contrastive Learning using Random Feature Corruption](https://mlsanity.com/paper/2106.15147/) (2021)
- [On the Challenges and Perspectives of Foundation Models for Medical Image Analysis](https://mlsanity.com/paper/2306.05705/) (2023)
- [XTab: Cross-table Pretraining for Tabular Transformers](https://mlsanity.com/paper/2305.06090/) (2023)
- [Best of Both Worlds: Multimodal Contrastive Learning with Tabular and Imaging Data](https://mlsanity.com/paper/2303.14080/) (2023)
- [AMLB: an AutoML Benchmark](https://mlsanity.com/paper/2207.12560/) (2022)
- [Cardiac Segmentation with Strong Anatomical Guarantees](https://mlsanity.com/paper/2006.08825/) (2020)
- [A Transformer-based representation-learning model with unified processing of multimodal input for clinical diagnostics](https://mlsanity.com/paper/2306.00864/) (2023)
- [Deep Representation Learning of Electronic Health Records to Unlock Patient Stratification at Scale](https://mlsanity.com/paper/2003.06516/) (2020)
- [Echocardiography Segmentation with Enforced Temporal Consistency](https://mlsanity.com/paper/2112.02102/) (2021)
- [Unimodal probability distributions for deep ordinal classification](https://mlsanity.com/paper/1705.05278/) (2017)
- [Rethinking Data Augmentation for Tabular Data in Deep Learning](https://mlsanity.com/paper/2305.10308/) (2023)
- [Unsupervised pre-training of graph transformers on patient population graphs](https://mlsanity.com/paper/2207.10603/) (2022)
- [Extraction of volumetric indices from echocardiography: which deep learning solution for clinical use?](https://mlsanity.com/paper/2305.01997/) (2023)
- [Stabilized Sparse Ordinal Regression for Medical Risk Stratification](https://mlsanity.com/paper/1407.6084/) (2014)

## Built on by (most cited first, 3 of 3)

- [DAFTED: Decoupled Asymmetric Fusion of Tabular and Echocardiographic Data for Cardiac Hypertension Diagnosis](https://mlsanity.com/paper/2509.15990/) (2025)
- [Anatomically Constrained Transformers for Cardiac Amyloidosis Classification](https://mlsanity.com/paper/2509.19691/) (2025)
- [AMF-MedIT: An Efficient Align-Modulation-Fusion Framework for Medical Image-Tabular Data](https://mlsanity.com/paper/2506.19439/) (2025)

## Abstract (arXiv)

Deep learning enables automatic and robust extraction of cardiac function descriptors from echocardiographic sequences, such as ejection fraction or strain. These descriptors provide fine-grained information that physicians consider, in conjunction with more global variables from the clinical record, to assess patients' condition. Drawing on novel Transformer models applied to tabular data, we propose a method that considers all descriptors extracted from medical records and echocardiograms to learn the representation of a cardiovascular pathology with a difficult-to-characterize continuum, namely hypertension. Our method first projects each variable into its own representation space using modality-specific approaches. These standardized representations of multimodal data are then fed to a Transformer encoder, which learns to merge them into a comprehensive representation of the patient through the task of predicting a clinical rating. This stratification task is formulated as an ordinal classification to enforce a pathological continuum in the representation space. We observe the major trends along this continuum on a cohort of 239 hypertensive patients, providing unprecedented details in the description of hypertension's impact on various cardiac function descriptors. Our analysis shows that i) the XTab foundation model's architecture allows to reach outstanding performance (96.8% AUROC) even with limited data (less than 200 training samples), ii) stratification across the population is reproducible between trainings (within 5.7% mean absolute error), and iii) patterns emerge in descriptors, some of which align with established physiological knowledge about hypertension, while others could pave the way for a more comprehensive understanding of this pathology. Code is available at https://github.com/creatis-myriad/didactic.
