# How to Efficiently Annotate Images for Best-Performing Deep Learning Based Segmentation Models: An Empirical Study with Weak and Noisy Annotations and Segment Anything Model

arXiv: https://arxiv.org/abs/2312.10600 · HTML: https://mlsanity.com/paper/2312.10600/

## Key facts

- Cited by 7 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 59 references that are in the map.
- First posted on arXiv 17 Dec 2023.

## Builds on (most cited first, 30 of 30)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [Pyramid Scene Parsing Network](https://mlsanity.com/paper/1612.01105/) (2016)
- [SimMIM: A Simple Framework for Masked Image Modeling](https://mlsanity.com/paper/2111.09886/) (2021)
- [Semantic Understanding of Scenes through the ADE20K Dataset](https://mlsanity.com/paper/1608.05442/) (2016)
- [Semantic Image Segmentation with Deep Convolutional Nets and Fully Connected CRFs](https://mlsanity.com/paper/1412.7062/) (2014)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [Semi-Supervised Semantic Segmentation with Cross Pseudo Supervision](https://mlsanity.com/paper/2106.01226/) (2021)
- [Semi-Supervised Semantic Segmentation with Cross-Consistency Training](https://mlsanity.com/paper/2003.09005/) (2020)
- [ScribbleSup: Scribble-Supervised Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1604.05144/) (2016)
- [Segment Anything Model for Medical Image Analysis: an Experimental Study](https://mlsanity.com/paper/2304.10517/) (2023)
- [Simple Does It: Weakly Supervised Instance and Semantic Segmentation](https://mlsanity.com/paper/1603.07485/) (2016)
- [Segment Anything in Medical Images](https://mlsanity.com/paper/2304.12306/) (2023)
- [Weakly- and Semi-Supervised Learning of a DCNN for Semantic Image Segmentation](https://mlsanity.com/paper/1502.02734/) (2015)
- [Reviving Iterative Training with Mask Guidance for Interactive Segmentation](https://mlsanity.com/paper/2102.06583/) (2021)
- [On Regularized Losses for Weakly-supervised CNN Segmentation](https://mlsanity.com/paper/1803.09569/) (2018)
- [FocalClick: Towards Practical Interactive Image Segmentation](https://mlsanity.com/paper/2204.02574/) (2022)
- [Image Classification with Deep Learning in the Presence of Noisy Labels: A Survey](https://mlsanity.com/paper/1912.05170/) (2019)
- [Box-driven Class-wise Region Masking and Filling Rate Guided Loss for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/1904.11693/) (2019)
- [Learning to Segment Medical Images with Scribble-Supervision Alone](https://mlsanity.com/paper/1807.04668/) (2018)
- [Background-Aware Pooling and Noise-Aware Loss for Weakly-Supervised Semantic Segmentation](https://mlsanity.com/paper/2104.00905/) (2021)
- [Omni-DETR: Omni-Supervised Object Detection with Transformers](https://mlsanity.com/paper/2203.16089/) (2022)
- [Can Image-Level Labels Replace Pixel-Level Labels for Image Parsing](https://mlsanity.com/paper/1403.1626/) (2014)
- [Imperfect Segmentation Labels: How Much Do They Matter?](https://mlsanity.com/paper/1806.04618/) (2018)
- [Hyperspectral Image Classification in the Presence of Noisy Labels](https://mlsanity.com/paper/1809.04212/) (2018)
- [Label noise in segmentation networks : mitigation must deal with bias](https://mlsanity.com/paper/2107.02189/) (2021)

## Built on by (most cited first, 7 of 7)

- [Noisy Annotations in Semantic Segmentation](https://mlsanity.com/paper/2406.10891/) (2024)
- [Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Models](https://mlsanity.com/paper/2404.13239/) (2024)
- [Semi-Supervised Object Detection: A Survey on Progress from CNN to Transformer](https://mlsanity.com/paper/2407.08460/) (2024)
- [How to select slices for annotation to train best-performing deep learning segmentation models for cross-sectional medical images?](https://mlsanity.com/paper/2412.08081/) (2024)
- [SegAssess: Panoramic quality mapping for robust and transferable unsupervised segmentation assessment](https://mlsanity.com/paper/2509.01183/) (2025)
- [IndoorCrowd: A Multi-Scene Dataset for Human Detection, Segmentation, and Tracking with an Automated Annotation Pipeline](https://mlsanity.com/paper/2604.02032/) (2026)
- [A Multi-Annotator Study of Segmentation Noise and Uncertainty in Turbid Underwater Images](https://mlsanity.com/paper/2608.15363/) (2026)

## Abstract (arXiv)

Deep neural networks (DNNs) have demonstrated exceptional performance across various image segmentation tasks. However, the process of preparing datasets for training segmentation DNNs is both labor-intensive and costly, as it typically requires pixel-level annotations for each object of interest. To mitigate this challenge, alternative approaches such as using weak labels (e.g., bounding boxes or scribbles) or less precise (noisy) annotations can be employed. Noisy and weak labels are significantly quicker to generate, allowing for more annotated images within the same time frame. However, the potential decrease in annotation quality may adversely impact the segmentation performance of the resulting model. In this study, we conducted a comprehensive cost-effectiveness evaluation on six variants of annotation strategies (9~10 sub-variants in total) across 4 datasets and conclude that the common practice of precisely outlining objects of interest is virtually never the optimal approach when annotation budget is limited. Both noisy and weak annotations showed usage cases that yield similar performance to the perfectly annotated counterpart, yet had significantly better cost-effectiveness. We hope our findings will help researchers be aware of the different available options and use their annotation budgets more efficiently, especially in cases where accurately acquiring labels for target objects is particularly costly. Our code will be made available on https://github.com/yzluka/AnnotationEfficiency2D.
