# ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentation

arXiv: https://arxiv.org/abs/2312.10585 · HTML: https://mlsanity.com/paper/2312.10585/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 84 references that are in the map.
- First posted on arXiv 17 Dec 2023.

## Builds on (most cited first, 30 of 30)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [Searching for MobileNetV3](https://mlsanity.com/paper/1905.02244/) (2019)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [SqueezeNet: AlexNet-level accuracy with 50x fewer parameters and <0.5MB model size](https://mlsanity.com/paper/1602.07360/) (2016)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1710.05006/) (2017)
- [Predicting Depth, Surface Normals and Semantic Labels with a Common Multi-Scale Convolutional Architecture](https://mlsanity.com/paper/1411.4734/) (2014)
- [Structure-measure: A New Way to Evaluate Foreground Maps](https://mlsanity.com/paper/1708.00786/) (2017)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [Enhanced-alignment Measure for Binary Foreground Map Evaluation](https://mlsanity.com/paper/1805.10421/) (2018)
- [ResUNet++: An Advanced Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1911.07067/) (2019)
- [UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformer](https://mlsanity.com/paper/2109.04335/) (2021)
- [Bi-Directional ConvLSTM U-Net with Densley Connected Convolutions](https://mlsanity.com/paper/1909.00166/) (2019)
- [ExpandNets: Linear Over-parameterization to Train Compact Convolutional Networks](https://mlsanity.com/paper/1811.10495/) (2018)
- [Depthwise Convolution is All You Need for Learning Multiple Visual Domains](https://mlsanity.com/paper/1902.00927/) (2019)
- [Deep Retinal Image Understanding](https://mlsanity.com/paper/1609.01103/) (2016)
- [Retinal vessel segmentation based on Fully Convolutional Neural Networks](https://mlsanity.com/paper/1812.07110/) (2018)
- [BiO-Net: Learning Recurrent Bi-directional Connections for Encoder-Decoder Architecture](https://mlsanity.com/paper/2007.00243/) (2020)
- [RepSR: Training Efficient VGG-style Super-Resolution Networks with Structural Re-Parameterization and Batch Normalization](https://mlsanity.com/paper/2205.05671/) (2022)
- [Retinal Vessel Segmentation via a Multi-resolution Contextual Network and Adversarial Learning](https://mlsanity.com/paper/2304.12856/) (2023)
- [Leveraging Image Complexity in Macro-Level Neural Network Design for Medical Image Segmentation](https://mlsanity.com/paper/2112.11065/) (2021)
- [MKIS-Net: A Light-Weight Multi-Kernel Network for Medical Image Segmentation](https://mlsanity.com/paper/2210.08168/) (2022)
- [RC-Net: A Convolutional Neural Network for Retinal Vessel Segmentation](https://mlsanity.com/paper/2112.11078/) (2021)
- [Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentation](https://mlsanity.com/paper/2309.03535/) (2023)
- [Connection Sensitive Attention U-NET for Accurate Retinal Vessel Segmentation](https://mlsanity.com/paper/1903.05558/) (2019)
- [LMBiS-Net: A Lightweight Multipath Bidirectional Skip Connection based CNN for Retinal Blood Vessel Segmentation](https://mlsanity.com/paper/2309.04968/) (2023)
- [DPN: Detail-Preserving Network with High Resolution Representation for Efficient Segmentation of Retinal Vessels](https://mlsanity.com/paper/2009.12053/) (2020)

## Built on by (most cited first, 9 of 9)

- [Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Images](https://mlsanity.com/paper/2405.17520/) (2024)
- [TBConvL-Net: A Hybrid Deep Learning Architecture for Robust Medical Image Segmentation](https://mlsanity.com/paper/2409.03367/) (2024)
- [LMBF-Net: A Lightweight Multipath Bidirectional Focal Attention Network for Multifeatures Segmentation](https://mlsanity.com/paper/2407.02871/) (2024)
- [Region Guided Attention Network for Retinal Vessel Segmentation](https://mlsanity.com/paper/2407.18970/) (2024)
- [EUIS-Net: A Convolutional Neural Network for Efficient Ultrasound Image Segmentation](https://mlsanity.com/paper/2408.12323/) (2024)
- [LFRA-Net: A Lightweight Focal and Region-Aware Attention Network for Retinal Vessel Segmentatio](https://mlsanity.com/paper/2509.11811/) (2025)
- [Focal Modulation and Bidirectional Feature Fusion Network for Medical Image Segmentation](https://mlsanity.com/paper/2510.20933/) (2025)
- [A Lightweight Multi-Scale Attention Framework for Real-Time Spinal Endoscopic Instance Segmentation](https://mlsanity.com/paper/2512.21984/) (2025)
- [MS-DKC: A Dataset Knowledge Card Framework for Designing and Adapting Medical Image Segmentation Models](https://mlsanity.com/paper/2606.06103/) (2026)

## Abstract (arXiv)

Segmentation is an important task in a wide range of computer vision applications, including medical image analysis. Recent years have seen an increase in the complexity of medical image segmentation approaches based on sophisticated convolutional neural network architectures. This progress has led to incremental enhancements in performance on widely recognised benchmark datasets. However, most of the existing approaches are computationally demanding, which limits their practical applicability. This paper presents an expand-squeeze dual multiscale residual network (ESDMR-Net), which is a fully convolutional network that is particularly well-suited for resource-constrained computing hardware such as mobile devices. ESDMR-Net focuses on extracting multiscale features, enabling the learning of contextual dependencies among semantically distinct features. The ESDMR-Net architecture allows dual-stream information flow within encoder-decoder pairs. The expansion operation (depthwise separable convolution) makes all of the rich features with multiscale information available to the squeeze operation (bottleneck layer), which then extracts the necessary information for the segmentation task. The Expand-Squeeze (ES) block helps the network pay more attention to under-represented classes, which contributes to improved segmentation accuracy. To enhance the flow of information across multiple resolutions or scales, we integrated dual multiscale residual (DMR) blocks into the skip connection. This integration enables the decoder to access features from various levels of abstraction, ultimately resulting in more comprehensive feature representations. We present experiments on seven datasets from five distinct examples of applications. Our model achieved the best results despite having significantly fewer trainable parameters, with a reduction of two or even three orders of magnitude.