# Sequence adaptive field-imperfection estimation (SAFE): retrospective estimation and correction of B1^+ and B0 inhomogeneities for enhanced MRF quantification

arXiv: https://arxiv.org/abs/2312.09488 · HTML: https://mlsanity.com/paper/2312.09488/

## Key facts

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- First posted on arXiv 15 Dec 2023.

## Abstract (arXiv)

B1^+ and B0 field-inhomogeneities can significantly reduce accuracy and robustness of MRF's quantitative parameter estimates. Additional B1^+ and B0 calibration scans can mitigate this but add scan time and cannot be applied retrospectively to previously collected data. Here, we proposed a calibration-free sequence-adaptive deep-learning framework, to estimate and correct for B1^+ and B0 effects of any MRF sequence. We demonstrate its capability on arbitrary MRF sequences at 3T, where no training data were previously obtained. Such approach can be applied to any previously-acquired and future MRF-scans. The flexibility in directly applying this framework to other quantitative sequences is also highlighted.