# Universal Adversarial Framework to Improve Adversarial Robustness for Diabetic Retinopathy Detection

arXiv: https://arxiv.org/abs/2312.08193 · HTML: https://mlsanity.com/paper/2312.08193/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 18 of its 40 references that are in the map.
- First posted on arXiv 13 Dec 2023.

## Builds on (most cited first, 18 of 18)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Explaining and Harnessing Adversarial Examples](https://mlsanity.com/paper/1412.6572/) (2014)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Towards Deep Learning Models Resistant to Adversarial Attacks](https://mlsanity.com/paper/1706.06083/) (2017)
- [Rethinking the Inception Architecture for Computer Vision](https://mlsanity.com/paper/1512.00567/) (2015)
- [MobileNetV2: Inverted Residuals and Linear Bottlenecks](https://mlsanity.com/paper/1801.04381/) (2018)
- [MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applications](https://mlsanity.com/paper/1704.04861/) (2017)
- [A ConvNet for the 2020s](https://mlsanity.com/paper/2201.03545/) (2022)
- [Inception-v4, Inception-ResNet and the Impact of Residual Connections on Learning](https://mlsanity.com/paper/1602.07261/) (2016)
- [DeepFool: a simple and accurate method to fool deep neural networks](https://mlsanity.com/paper/1511.04599/) (2015)
- [Learning Transferable Architectures for Scalable Image Recognition](https://mlsanity.com/paper/1707.07012/) (2017)
- [Universal adversarial perturbations](https://mlsanity.com/paper/1610.08401/) (2016)
- [Maximal Jacobian-based Saliency Map Attack](https://mlsanity.com/paper/1808.07945/) (2018)
- [RegNet: Self-Regulated Network for Image Classification](https://mlsanity.com/paper/2101.00590/) (2021)
- [Vulnerability Analysis of Chest X-Ray Image Classification Against Adversarial Attacks](https://mlsanity.com/paper/1807.02905/) (2018)

## Abstract (arXiv)

Diabetic Retinopathy (DR) is a prevalent illness associated with Diabetes which, if left untreated, can result in irreversible blindness. Deep Learning based systems are gradually being introduced as automated support for clinical diagnosis. Since healthcare has always been an extremely important domain demanding error-free performance, any adversaries could pose a big threat to the applicability of such systems. In this work, we use Universal Adversarial Perturbations (UAPs) to quantify the vulnerability of Medical Deep Neural Networks (DNNs) for detecting DR. To the best of our knowledge, this is the very first attempt that works on attacking complete fine-grained classification of DR images using various UAPs. Also, as a part of this work, we use UAPs to fine-tune the trained models to defend against adversarial samples. We experiment on several models and observe that the performance of such models towards unseen adversarial attacks gets boosted on average by 3.41 Cohen-kappa value and maximum by 31.92 Cohen-kappa value. The performance degradation on normal data upon ensembling the fine-tuned models was found to be statistically insignificant using t-test, highlighting the benefits of UAP-based adversarial fine-tuning.