# Medical Vision Language Pretraining: A survey

arXiv: https://arxiv.org/abs/2312.06224 · HTML: https://mlsanity.com/paper/2312.06224/

## Key facts

- Cited by 24 papers in the map (data through 14 Oct 2026).
- Placed in Medical vision-language models, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 114 of its 161 references that are in the map.
- First posted on arXiv 11 Dec 2023.

## Placed in

- Multimodal LLMs / vision-language models / [Medical vision-language models](https://mlsanity.com/mllm/medical-vision-language-models/)

## Builds on (most cited first, 30 of 114)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [A Simple Framework for Contrastive Learning of Visual Representations](https://mlsanity.com/paper/2002.05709/) (2020)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervision](https://mlsanity.com/paper/2102.05918/) (2021)
- [ViLBERT: Pretraining Task-Agnostic Visiolinguistic Representations for Vision-and-Language Tasks](https://mlsanity.com/paper/1908.02265/) (2019)
- [Visual Prompt Tuning](https://mlsanity.com/paper/2203.12119/) (2022)
- [LAION-400M: Open Dataset of CLIP-Filtered 400 Million Image-Text Pairs](https://mlsanity.com/paper/2111.02114/) (2021)
- [Show, Attend and Tell: Neural Image Caption Generation with Visual Attention](https://mlsanity.com/paper/1502.03044/) (2015)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [LLaVA-Med: Training a Large Language-and-Vision Assistant for Biomedicine in One Day](https://mlsanity.com/paper/2306.00890/) (2023)
- [VisualBERT: A Simple and Performant Baseline for Vision and Language](https://mlsanity.com/paper/1908.03557/) (2019)
- [Grounded Language-Image Pre-training](https://mlsanity.com/paper/2112.03857/) (2021)
- [Domain-Specific Language Model Pretraining for Biomedical Natural Language Processing](https://mlsanity.com/paper/2007.15779/) (2020)
- [Publicly Available Clinical BERT Embeddings](https://mlsanity.com/paper/1904.03323/) (2019)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classification](https://mlsanity.com/paper/2110.14795/) (2021)
- [Unified Language Model Pre-training for Natural Language Understanding and Generation](https://mlsanity.com/paper/1905.03197/) (2019)
- [Contrastive Learning of Medical Visual Representations from Paired Images and Text](https://mlsanity.com/paper/2010.00747/) (2020)
- [MedCLIP: Contrastive Learning from Unpaired Medical Images and Text](https://mlsanity.com/paper/2210.10163/) (2022)
- [BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs](https://mlsanity.com/paper/2303.00915/) (2023)
- [End-to-End Learning of Visual Representations from Uncurated Instructional Videos](https://mlsanity.com/paper/1912.06430/) (2019)
- [PathVQA: 30000+ Questions for Medical Visual Question Answering](https://mlsanity.com/paper/2003.10286/) (2020)
- [SLAKE: A Semantically-Labeled Knowledge-Enhanced Dataset for Medical Visual Question Answering](https://mlsanity.com/paper/2102.09542/) (2021)
- [Rotation Equivariant CNNs for Digital Pathology](https://mlsanity.com/paper/1806.03962/) (2018)

## Built on by (most cited first, 24 of 24)

- [Vision-Language Models for Medical Report Generation and Visual Question Answering: A Review](https://mlsanity.com/paper/2403.02469/) (2024)
- [Foundation Model for Advancing Healthcare: Challenges, Opportunities, and Future Directions](https://mlsanity.com/paper/2404.03264/) (2024)
- [Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey](https://mlsanity.com/paper/2408.12880/) (2024)
- [PromptSmooth: Certifying Robustness of Medical Vision-Language Models via Prompt Learning](https://mlsanity.com/paper/2408.16769/) (2024)
- [Hallucination-Aware Multimodal Benchmark for Gastrointestinal Image Analysis with Large Vision-Language Models](https://mlsanity.com/paper/2505.07001/) (2025)
- [Multimodal Federated Learning With Missing Modalities through Feature Imputation Network](https://mlsanity.com/paper/2505.20232/) (2025)
- [Pre-training on High Definition X-ray Images: An Experimental Study](https://mlsanity.com/paper/2404.17926/) (2024)
- [Masked Contrastive Reconstruction for Cross-modal Medical Image-Report Retrieval](https://mlsanity.com/paper/2312.15840/) (2023)
- [BenchX: A Unified Benchmark Framework for Medical Vision-Language Pretraining on Chest X-Rays](https://mlsanity.com/paper/2410.21969/) (2024)
- [CAR-MFL: Cross-Modal Augmentation by Retrieval for Multimodal Federated Learning with Missing Modalities](https://mlsanity.com/paper/2407.08648/) (2024)
- [Efficient Medical Vision-Language Alignment Through Adapting Masked Vision Models](https://mlsanity.com/paper/2506.08990/) (2025)
- [Medical Knowledge Intervention Prompt Tuning for Medical Image Classification](https://mlsanity.com/paper/2511.12639/) (2025)
- [TuneVLSeg: Prompt Tuning Benchmark for Vision-Language Segmentation Models](https://mlsanity.com/paper/2410.05239/) (2024)
- [6 Fingers, 1 Kidney: Natural Adversarial Medical Images Reveal Critical Weaknesses of Vision-Language Models](https://mlsanity.com/paper/2512.04238/) (2025)
- [Knowledge to Sight: Reasoning over Visual Attributes via Knowledge Decomposition for Abnormality Grounding](https://mlsanity.com/paper/2508.04572/) (2025)
- [Estimating 2D Keypoints of Surgical Tools Using Vision-Language Models with Low-Rank Adaptation](https://mlsanity.com/paper/2508.20830/) (2025)
- [Data-Efficient Fine-Tuning of Vision-Language Models for Diagnosis of Alzheimer's Disease](https://mlsanity.com/paper/2509.07613/) (2025)
- [Alignment, Mining and Fusion: Representation Alignment with Hard Negative Mining and Selective Knowledge Fusion for Medical Visual Question Answering](https://mlsanity.com/paper/2510.08791/) (2025)
- [Med-MMFL: A Multimodal Federated Learning Benchmark in Healthcare](https://mlsanity.com/paper/2602.04416/) (2026)
- [SJTU:Spatial judgments in multimodal models towards unified segmentation through coordinate detection](https://mlsanity.com/paper/2412.02565/) (2024)
- [CLIP-KOA: Enhancing Knee Osteoarthritis Diagnosis with Multi-Modal Learning and Symmetry-Aware Loss Functions](https://mlsanity.com/paper/2504.19443/) (2025)
- [Brain Imaging Foundation Models, Are We There Yet? A Systematic Review of Foundation Models for Brain Imaging and Biomedical Research](https://mlsanity.com/paper/2506.13306/) (2025)
- [Does medical specialization of VLMs enhance discriminative power?: A comprehensive investigation through feature distribution analysis](https://mlsanity.com/paper/2601.14774/) (2026)
- [ProMoE-FL: Prototype-conditioned Mixture of Experts for Multimodal Federated Learning with Missing Modalities](https://mlsanity.com/paper/2607.06633/) (2026)

## Abstract (arXiv)

Medical Vision Language Pretraining (VLP) has recently emerged as a promising solution to the scarcity of labeled data in the medical domain. By leveraging paired/unpaired vision and text datasets through self-supervised learning, models can be trained to acquire vast knowledge and learn robust feature representations. Such pretrained models have the potential to enhance multiple downstream medical tasks simultaneously, reducing the dependency on labeled data. However, despite recent progress and its potential, there is no such comprehensive survey paper that has explored the various aspects and advancements in medical VLP. In this paper, we specifically review existing works through the lens of different pretraining objectives, architectures, downstream evaluation tasks, and datasets utilized for pretraining and downstream tasks. Subsequently, we delve into current challenges in medical VLP, discussing existing and potential solutions, and conclude by highlighting future directions. To the best of our knowledge, this is the first survey focused on medical VLP.