# Explainable Severity ranking via pairwise n-hidden comparison: a case study of glaucoma

arXiv: https://arxiv.org/abs/2312.02541 · HTML: https://mlsanity.com/paper/2312.02541/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 22 references that are in the map.
- First posted on arXiv 5 Dec 2023.

## Builds on (most cited first, 9 of 9)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [A Unified Approach to Interpreting Model Predictions](https://mlsanity.com/paper/1705.07874/) (2017)
- ["Why Should I Trust You?": Explaining the Predictions of Any Classifier](https://mlsanity.com/paper/1602.04938/) (2016)
- [Axiomatic Attribution for Deep Networks](https://mlsanity.com/paper/1703.01365/) (2017)
- [Visualizing and Understanding Convolutional Networks](https://mlsanity.com/paper/1311.2901/) (2013)
- [Deep Learning the City : Quantifying Urban Perception At A Global Scale](https://mlsanity.com/paper/1608.01769/) (2016)

## Abstract (arXiv)

Primary open-angle glaucoma (POAG) is a chronic and progressive optic nerve condition that results in an acquired loss of optic nerve fibers and potential blindness. The gradual onset of glaucoma results in patients progressively losing their vision without being consciously aware of the changes. To diagnose POAG and determine its severity, patients must undergo a comprehensive dilated eye examination. In this work, we build a framework to rank, compare, and interpret the severity of glaucoma using fundus images. We introduce a siamese-based severity ranking using pairwise n-hidden comparisons. We additionally have a novel approach to explaining why a specific image is deemed more severe than others. Our findings indicate that the proposed severity ranking model surpasses traditional ones in terms of diagnostic accuracy and delivers improved saliency explanations.