# Segment Anything Model-guided Collaborative Learning Network for Scribble-supervised Polyp Segmentation

arXiv: https://arxiv.org/abs/2312.00312 · HTML: https://mlsanity.com/paper/2312.00312/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 56 references that are in the map.
- First posted on arXiv 1 Dec 2023.

## Builds on (most cited first, 14 of 14)

- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Weakly-Supervised Concealed Object Segmentation with SAM-based Pseudo Labeling and Multi-scale Feature Grouping](https://mlsanity.com/paper/2305.11003/) (2023)
- [Context-aware Cross-level Fusion Network for Camouflaged Object Detection](https://mlsanity.com/paper/2105.12555/) (2021)
- [HarDNet-MSEG: A Simple Encoder-Decoder Polyp Segmentation Neural Network that Achieves over 0.9 Mean Dice and 86 FPS](https://mlsanity.com/paper/2101.07172/) (2021)
- [Polyp-SAM: Transfer SAM for Polyp Segmentation](https://mlsanity.com/paper/2305.00293/) (2023)
- [Can SAM Segment Polyps?](https://mlsanity.com/paper/2304.07583/) (2023)
- [SAM Fails to Segment Anything? -- SAM-Adapter: Adapting SAM in Underperformed Scenes: Camouflage, Shadow, Medical Image Segmentation, and More](https://mlsanity.com/paper/2304.09148/) (2023)
- [Segment Anything Model (SAM) Enhanced Pseudo Labels for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2305.05803/) (2023)
- [Segment Anything is A Good Pseudo-label Generator for Weakly Supervised Semantic Segmentation](https://mlsanity.com/paper/2305.01275/) (2023)
- [Polyp-SAM++: Can A Text Guided SAM Perform Better for Polyp Segmentation?](https://mlsanity.com/paper/2308.06623/) (2023)
- [An Alternative to WSSS? An Empirical Study of the Segment Anything Model (SAM) on Weakly-Supervised Semantic Segmentation Problems](https://mlsanity.com/paper/2305.01586/) (2023)
- [Weakly-Supervised Semantic Segmentation with Image-Level Labels: from Traditional Models to Foundation Models](https://mlsanity.com/paper/2310.13026/) (2023)
- [SamDSK: Combining Segment Anything Model with Domain-Specific Knowledge for Semi-Supervised Learning in Medical Image Segmentation](https://mlsanity.com/paper/2308.13759/) (2023)
- [YONA: You Only Need One Adjacent Reference-frame for Accurate and Fast Video Polyp Detection](https://mlsanity.com/paper/2306.03686/) (2023)

## Built on by (most cited first, 2 of 2)

- [Beyond Pixel-Wise Supervision for Medical Image Segmentation: From Traditional Models to Foundation Models](https://mlsanity.com/paper/2404.13239/) (2024)
- [SparseMamba-PCL: Scribble-Supervised Medical Image Segmentation via SAM-Guided Progressive Collaborative Learning](https://mlsanity.com/paper/2503.01633/) (2025)

## Abstract (arXiv)

Polyp segmentation plays a vital role in accurately locating polyps at an early stage, which holds significant clinical importance for the prevention of colorectal cancer. Various polyp segmentation methods have been developed using fully-supervised deep learning techniques. However, pixel-wise annotation for polyp images by physicians during the diagnosis is both time-consuming and expensive. Moreover, visual foundation models such as the Segment Anything Model (SAM) have shown remarkable performance. Nevertheless, directly applying SAM to medical segmentation may not produce satisfactory results due to the inherent absence of medical knowledge. In this paper, we propose a novel SAM-guided Collaborative Learning Network (SAM-CLNet) for scribble-supervised polyp segmentation, enabling a collaborative learning process between our segmentation network and SAM to boost the model performance. Specifically, we first propose a Cross-level Enhancement and Aggregation Network (CEA-Net) for weakly-supervised polyp segmentation. Within CEA-Net, we propose a Cross-level Enhancement Module (CEM) that integrates the adjacent features to enhance the representation capabilities of different resolution features. Additionally, a Feature Aggregation Module (FAM) is employed to capture richer features across multiple levels. Moreover, we present a box-augmentation strategy that combines the segmentation maps generated by CEA-Net with scribble annotations to create more precise prompts. These prompts are then fed into SAM, generating segmentation SAM-guided masks, which can provide additional supervision to train CEA-Net effectively. Furthermore, we present an Image-level Filtering Mechanism to filter out unreliable SAM-guided masks. Extensive experimental results show that our SAM-CLNet outperforms state-of-the-art weakly-supervised segmentation methods.