# Clean Label Disentangling for Medical Image Segmentation with Noisy Labels

arXiv: https://arxiv.org/abs/2311.16580 · HTML: https://mlsanity.com/paper/2311.16580/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 44 of its 55 references that are in the map.
- First posted on arXiv 28 Nov 2023.

## Builds on (most cited first, 30 of 44)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Batch Normalization: Accelerating Deep Network Training by Reducing Internal Covariate Shift](https://mlsanity.com/paper/1502.03167/) (2015)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [Rethinking Atrous Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1706.05587/) (2017)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Co-teaching: Robust Training of Deep Neural Networks with Extremely Noisy Labels](https://mlsanity.com/paper/1804.06872/) (2018)
- [Semantic Image Segmentation with Deep Convolutional Nets and Fully Connected CRFs](https://mlsanity.com/paper/1412.7062/) (2014)
- [Symmetric Cross Entropy for Robust Learning with Noisy Labels](https://mlsanity.com/paper/1908.06112/) (2019)
- [Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.12620/) (2023)
- [Robust Loss Functions under Label Noise for Deep Neural Networks](https://mlsanity.com/paper/1712.09482/) (2017)
- [Deep Learning for Medical Image Analysis](https://mlsanity.com/paper/1708.08987/) (2017)
- [Semi-Supervised Semantic Segmentation Using Unreliable Pseudo-Labels](https://mlsanity.com/paper/2203.03884/) (2022)
- [Are Anchor Points Really Indispensable in Label-Noise Learning?](https://mlsanity.com/paper/1906.00189/) (2019)
- [UNeXt: MLP-based Rapid Medical Image Segmentation Network](https://mlsanity.com/paper/2203.04967/) (2022)
- [Revisiting Weak-to-Strong Consistency in Semi-Supervised Semantic Segmentation](https://mlsanity.com/paper/2208.09910/) (2022)
- [M2m: Imbalanced Classification via Major-to-minor Translation](https://mlsanity.com/paper/2004.00431/) (2020)
- [Bidirectional Copy-Paste for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2305.00673/) (2023)
- [Perturbed and Strict Mean Teachers for Semi-supervised Semantic Segmentation](https://mlsanity.com/paper/2111.12903/) (2021)
- [Mutual Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2109.09960/) (2021)
- [Semi-Supervised Medical Image Segmentation via Cross Teaching between CNN and Transformer](https://mlsanity.com/paper/2112.04894/) (2021)
- [Provably End-to-end Label-Noise Learning without Anchor Points](https://mlsanity.com/paper/2102.02400/) (2021)
- [Exploring Smoothness and Class-Separation for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2203.01324/) (2022)
- [Combo Loss: Handling Input and Output Imbalance in Multi-Organ Segmentation](https://mlsanity.com/paper/1805.02798/) (2018)
- [CycleMix: A Holistic Strategy for Medical Image Segmentation from Scribble Supervision](https://mlsanity.com/paper/2203.01475/) (2022)
- [Scribble-Supervised Medical Image Segmentation via Dual-Branch Network and Dynamically Mixed Pseudo Labels Supervision](https://mlsanity.com/paper/2203.02106/) (2022)
- [Augmentation Matters: A Simple-yet-Effective Approach to Semi-supervised Semantic Segmentation](https://mlsanity.com/paper/2212.04976/) (2022)

## Abstract (arXiv)

Current methods focusing on medical image segmentation suffer from incorrect annotations, which is known as the noisy label issue. Most medical image segmentation with noisy labels methods utilize either noise transition matrix, noise-robust loss functions or pseudo-labeling methods, while none of the current research focuses on clean label disentanglement. We argue that the main reason is that the severe class-imbalanced issue will lead to the inaccuracy of the selected ``clean'' labels, thus influencing the robustness of the model against the noises. In this work, we come up with a simple but efficient class-balanced sampling strategy to tackle the class-imbalanced problem, which enables our newly proposed clean label disentangling framework to successfully select clean labels from the given label sets and encourages the model to learn from the correct annotations. However, such a method will filter out too many annotations which may also contain useful information. Therefore, we further extend our clean label disentangling framework to a new noisy feature-aided clean label disentangling framework, which takes the full annotations into utilization to learn more semantics. Extensive experiments have validated the effectiveness of our methods, where our methods achieve new state-of-the-art performance. Our code is available at https://github.com/xiaoyao3302/2BDenoise.
