# Only Positive Cases: 5-fold High-order Attention Interaction Model for Skin Segmentation Derived Classification

arXiv: https://arxiv.org/abs/2311.15625 · HTML: https://mlsanity.com/paper/2311.15625/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 18 of its 27 references that are in the map.
- First posted on arXiv 27 Nov 2023.

## Builds on (most cited first, 18 of 18)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1710.05006/) (2017)
- [Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.12620/) (2023)
- [Global Filter Networks for Image Classification](https://mlsanity.com/paper/2107.00645/) (2021)
- [Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentation](https://mlsanity.com/paper/1802.06955/) (2018)
- [HorNet: Efficient High-Order Spatial Interactions with Recursive Gated Convolutions](https://mlsanity.com/paper/2207.14284/) (2022)
- [Squeeze-and-Attention Networks for Semantic Segmentation](https://mlsanity.com/paper/1909.03402/) (2019)
- [MALUNet: A Multi-Attention and Light-weight UNet for Skin Lesion Segmentation](https://mlsanity.com/paper/2211.01784/) (2022)
- [TransNorm: Transformer Provides a Strong Spatial Normalization Mechanism for a Deep Segmentation Model](https://mlsanity.com/paper/2207.13415/) (2022)
- [Multi-level Context Gating of Embedded Collective Knowledge for Medical Image Segmentation](https://mlsanity.com/paper/2003.05056/) (2020)
- [A survey, review, and future trends of skin lesion segmentation and classification](https://mlsanity.com/paper/2208.12232/) (2022)
- [Attention Swin U-Net: Cross-Contextual Attention Mechanism for Skin Lesion Segmentation](https://mlsanity.com/paper/2210.16898/) (2022)
- [CDDSA: Contrastive Domain Disentanglement and Style Augmentation for Generalizable Medical Image Segmentation](https://mlsanity.com/paper/2211.12081/) (2022)

## Built on by (most cited first, 1 of 1)

- [H-vmunet: High-order Vision Mamba UNet for Medical Image Segmentation](https://mlsanity.com/paper/2403.13642/) (2024)

## Abstract (arXiv)

Computer-aided diagnosis of skin diseases is an important tool. However, the interpretability of computer-aided diagnosis is currently poor. Dermatologists and patients cannot intuitively understand the learning and prediction process of neural networks, which will lead to a decrease in the credibility of computer-aided diagnosis. In addition, traditional methods need to be trained using negative samples in order to predict the presence or absence of a lesion, but medical data is often in short supply. In this paper, we propose a multiple high-order attention interaction model (MHA-UNet) for use in a highly explainable skin lesion segmentation task. MHA-UNet is able to obtain the presence or absence of a lesion by explainable reasoning without the need for training on negative samples. Specifically, we propose a high-order attention interaction mechanism that introduces squeeze attention to a higher level for feature attention. In addition, a multiple high-order attention interaction (MHAblock) module is proposed by combining the different features of different orders. For classifying the presence or absence of lesions, we conducted classification experiments on several publicly available datasets in the absence of negative samples, based on explainable reasoning about the interaction of 5 attention orders of MHAblock. The highest positive detection rate obtained from the experiments was 81.0% and the highest negative detection rate was 83.5%. For segmentation experiments, comparison experiments of the proposed method with 13 medical segmentation models and external validation experiments with 8 state-of-the-art models in three public datasets and our clinical dataset demonstrate the state-of-the-art performance of our model. The code is available from https://github.com/wurenkai/MHA-UNet.