# From Classification to Clinical Insights: Towards Analyzing and Reasoning About Mobile and Behavioral Health Data With Large Language Models

arXiv: https://arxiv.org/abs/2311.13063 · HTML: https://mlsanity.com/paper/2311.13063/

## Key facts

- Cited by 11 papers in the map (data through 14 Oct 2026).
- Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning.
- Builds on 28 of its 82 references that are in the map.
- First posted on arXiv 21 Nov 2023.

## Placed in

- LLM reasoning / [Clinical and biomedical applications](https://mlsanity.com/lr/clinical-and-biomedical-applications/)

## Builds on (most cited first, 28 of 28)

- [BERT: Pre-training of Deep Bidirectional Transformers for Language Understanding](https://mlsanity.com/paper/1810.04805/) (2018)
- [GPT-4 Technical Report](https://mlsanity.com/paper/2303.08774/) (2023)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [Chain-of-Thought Prompting Elicits Reasoning in Large Language Models](https://mlsanity.com/paper/2201.11903/) (2022)
- [Self-Consistency Improves Chain of Thought Reasoning in Language Models](https://mlsanity.com/paper/2203.11171/) (2022)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Finetuned Language Models Are Zero-Shot Learners](https://mlsanity.com/paper/2109.01652/) (2021)
- [Lost in the Middle: How Language Models Use Long Contexts](https://mlsanity.com/paper/2307.03172/) (2023)
- [Scaling Instruction-Finetuned Language Models](https://mlsanity.com/paper/2210.11416/) (2022)
- [Sparks of Artificial General Intelligence: Early experiments with GPT-4](https://mlsanity.com/paper/2303.12712/) (2023)
- [Least-to-Most Prompting Enables Complex Reasoning in Large Language Models](https://mlsanity.com/paper/2205.10625/) (2022)
- [Distilling Step-by-Step! Outperforming Larger Language Models with Less Training Data and Smaller Model Sizes](https://mlsanity.com/paper/2305.02301/) (2023)
- [BBQ: A Hand-Built Bias Benchmark for Question Answering](https://mlsanity.com/paper/2110.08193/) (2021)
- [Capabilities of GPT-4 on Medical Challenge Problems](https://mlsanity.com/paper/2303.13375/) (2023)
- [Is ChatGPT a General-Purpose Natural Language Processing Task Solver?](https://mlsanity.com/paper/2302.06476/) (2023)
- [Llemma: An Open Language Model For Mathematics](https://mlsanity.com/paper/2310.10631/) (2023)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [ChatDoctor: A Medical Chat Model Fine-Tuned on a Large Language Model Meta-AI (LLaMA) Using Medical Domain Knowledge](https://mlsanity.com/paper/2303.14070/) (2023)
- [On Second Thought, Let's Not Think Step by Step! Bias and Toxicity in Zero-Shot Reasoning](https://mlsanity.com/paper/2212.08061/) (2022)
- [Can ChatGPT Understand Too? A Comparative Study on ChatGPT and Fine-tuned BERT](https://mlsanity.com/paper/2302.10198/) (2023)
- [Large Language Models are Few-Shot Health Learners](https://mlsanity.com/paper/2305.15525/) (2023)
- [PMC-LLaMA: Towards Building Open-source Language Models for Medicine](https://mlsanity.com/paper/2304.14454/) (2023)
- [Evaluation of ChatGPT for NLP-based Mental Health Applications](https://mlsanity.com/paper/2303.15727/) (2023)
- [Towards Interpretable Mental Health Analysis with Large Language Models](https://mlsanity.com/paper/2304.03347/) (2023)
- [ChatGPT versus Traditional Question Answering for Knowledge Graphs: Current Status and Future Directions Towards Knowledge Graph Chatbots](https://mlsanity.com/paper/2302.06466/) (2023)
- [Will Affective Computing Emerge from Foundation Models and General AI? A First Evaluation on ChatGPT](https://mlsanity.com/paper/2303.03186/) (2023)
- [Probing Explicit and Implicit Gender Bias through LLM Conditional Text Generation](https://mlsanity.com/paper/2311.00306/) (2023)
- [Effective Distillation of Table-based Reasoning Ability from LLMs](https://mlsanity.com/paper/2309.13182/) (2023)

## Built on by (most cited first, 11 of 11)

- [Health-LLM: Large Language Models for Health Prediction via Wearable Sensor Data](https://mlsanity.com/paper/2401.06866/) (2024)
- [MindScape Study: Integrating LLM and Behavioral Sensing for Personalized AI-Driven Journaling Experiences](https://mlsanity.com/paper/2409.09570/) (2024)
- [Transforming Wearable Data into Personal Health Insights using Large Language Model Agents](https://mlsanity.com/paper/2406.06464/) (2024)
- [Evaluating Large Language Models as Virtual Annotators for Time-series Physical Sensing Data](https://mlsanity.com/paper/2403.01133/) (2024)
- [SensorChat: Answering Qualitative and Quantitative Questions during Long-Term Multimodal Sensor Interactions](https://mlsanity.com/paper/2502.02883/) (2025)
- [SensorQA: A Question Answering Benchmark for Daily-Life Monitoring](https://mlsanity.com/paper/2501.04974/) (2025)
- [Exploring Personalized Health Support through Data-Driven, Theory-Guided LLMs: A Case Study in Sleep Health](https://mlsanity.com/paper/2502.13920/) (2025)
- [Vital Insight: Assisting Experts' Context-Driven Sensemaking of Multi-modal Personal Tracking Data Using Visualization and Human-In-The-Loop LLM](https://mlsanity.com/paper/2410.14879/) (2024)
- [A Survey of Foundation Models for IoT: Taxonomy and Criteria-Based Analysis](https://mlsanity.com/paper/2506.12263/) (2025)
- [Deep Learning-Based Detection of Cognitive Impairment from Passive Smartphone Sensing with Routine-Aware Augmentation and Demographic Personalization](https://mlsanity.com/paper/2509.23158/) (2025)
- [Not All Nudges Land: Behavioral Controllability and Elaboration Quality in AI-Supported Journaling](https://mlsanity.com/paper/2608.12582/) (2026)

## Abstract (arXiv)

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical practice requires addressing challenges of generalization across devices and weak or ambiguous correlations between the measured signals and an individual's mental health. To address these challenges, we take a novel approach that leverages large language models (LLMs) to synthesize clinically useful insights from multi-sensor data. We develop chain of thought prompting methods that use LLMs to generate reasoning about how trends in data such as step count and sleep relate to conditions like depression and anxiety. We first demonstrate binary depression classification with LLMs achieving accuracies of 61.1% which exceed the state of the art. While it is not robust for clinical use, this leads us to our key finding: even more impactful and valued than classification is a new human-AI collaboration approach in which clinician experts interactively query these tools and combine their domain expertise and context about the patient with AI generated reasoning to support clinical decision-making. We find models like GPT-4 correctly reference numerical data 75% of the time, and clinician participants express strong interest in using this approach to interpret self-tracking data.
