# A Region of Interest Focused Triple UNet Architecture for Skin Lesion Segmentation

arXiv: https://arxiv.org/abs/2311.12581 · HTML: https://mlsanity.com/paper/2311.12581/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 32 of its 58 references that are in the map.
- First posted on arXiv 21 Nov 2023.

## Builds on (most cited first, 30 of 32)

- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Non-local Neural Networks](https://mlsanity.com/paper/1711.07971/) (2017)
- [UNet++: A Nested U-Net Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1807.10165/) (2018)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Dual Attention Network for Scene Segmentation](https://mlsanity.com/paper/1809.02983/) (2018)
- [CCNet: Criss-Cross Attention for Semantic Segmentation](https://mlsanity.com/paper/1811.11721/) (2018)
- [Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1902.03368/) (2019)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentation](https://mlsanity.com/paper/2004.08790/) (2020)
- [BCN20000: Dermoscopic Lesions in the Wild](https://mlsanity.com/paper/1908.02288/) (2019)
- [ResUNet++: An Advanced Architecture for Medical Image Segmentation](https://mlsanity.com/paper/1911.07067/) (2019)
- [Skin Lesion Analysis toward Melanoma Detection: A Challenge at the International Symposium on Biomedical Imaging (ISBI) 2016, hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1605.01397/) (2016)
- [MultiResUNet : Rethinking the U-Net Architecture for Multimodal Biomedical Image Segmentation](https://mlsanity.com/paper/1902.04049/) (2019)
- [A Novel Focal Tversky loss function with improved Attention U-Net for lesion segmentation](https://mlsanity.com/paper/1810.07842/) (2018)
- [DoubleU-Net: A Deep Convolutional Neural Network for Medical Image Segmentation](https://mlsanity.com/paper/2006.04868/) (2020)
- [Bi-Directional ConvLSTM U-Net with Densley Connected Convolutions](https://mlsanity.com/paper/1909.00166/) (2019)
- [MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentation](https://mlsanity.com/paper/2105.07451/) (2021)
- [Multi-level Context Gating of Embedded Collective Knowledge for Medical Image Segmentation](https://mlsanity.com/paper/2003.05056/) (2020)
- [A survey, review, and future trends of skin lesion segmentation and classification](https://mlsanity.com/paper/2208.12232/) (2022)
- [The Effects of Skin Lesion Segmentation on the Performance of Dermatoscopic Image Classification](https://mlsanity.com/paper/2008.12602/) (2020)
- [Illumination-based Transformations Improve Skin Lesion Segmentation in Dermoscopic Images](https://mlsanity.com/paper/2003.10111/) (2020)
- [Automatic skin lesion segmentation on dermoscopic images by the means of superpixel merging](https://mlsanity.com/paper/1808.06759/) (2018)
- [Joint Demosaicking and Denoising Benefits from a Two-stage Training Strategy](https://mlsanity.com/paper/2009.06205/) (2020)
- [An Attention Module for Convolutional Neural Networks](https://mlsanity.com/paper/2108.08205/) (2021)
- [k-Means Clustering and Ensemble of Regressions: An Algorithm for the ISIC 2017 Skin Lesion Segmentation Challenge](https://mlsanity.com/paper/1702.07333/) (2017)
- [Segmenting Dermoscopic Images](https://mlsanity.com/paper/1703.03186/) (2017)
- [Automatic Skin Lesion Segmentation using Semi-supervised Learning Technique](https://mlsanity.com/paper/1703.04301/) (2017)

## Abstract (arXiv)

Skin lesion segmentation is of great significance for skin lesion analysis and subsequent treatment. It is still a challenging task due to the irregular and fuzzy lesion borders, and diversity of skin lesions. In this paper, we propose Triple-UNet to automatically segment skin lesions. It is an organic combination of three UNet architectures with suitable modules. In order to concatenate the first and second sub-networks more effectively, we design a region of interest enhancement module (ROIE). The ROIE enhances the target object region of the image by using the predicted score map of the first UNet. The features learned by the first UNet and the enhanced image help the second UNet obtain a better score map. Finally, the results are fine-tuned by the third UNet. We evaluate our algorithm on a publicly available dataset of skin lesion segmentation. Experiments show that Triple-UNet outperforms the state-of-the-art on skin lesion segmentation.