# Segment Together: A Versatile Paradigm for Semi-Supervised Medical Image Segmentation

arXiv: https://arxiv.org/abs/2311.11686 · HTML: https://mlsanity.com/paper/2311.11686/

## Key facts

- Cited by 12 papers in the map (data through 14 Oct 2026).
- Builds on 36 of its 45 references that are in the map.
- First posted on arXiv 20 Nov 2023.

## Builds on (most cited first, 30 of 36)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [CutMix: Regularization Strategy to Train Strong Classifiers with Localizable Features](https://mlsanity.com/paper/1905.04899/) (2019)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [FixMatch: Simplifying Semi-Supervised Learning with Consistency and Confidence](https://mlsanity.com/paper/2001.07685/) (2020)
- [Virtual Adversarial Training: A Regularization Method for Supervised and Semi-Supervised Learning](https://mlsanity.com/paper/1704.03976/) (2017)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [Uncertainty-aware Self-ensembling Model for Semi-supervised 3D Left Atrium Segmentation](https://mlsanity.com/paper/1907.07034/) (2019)
- [Visual-Language Prompt Tuning with Knowledge-guided Context Optimization](https://mlsanity.com/paper/2303.13283/) (2023)
- [In Defense of Pseudo-Labeling: An Uncertainty-Aware Pseudo-label Selection Framework for Semi-Supervised Learning](https://mlsanity.com/paper/2101.06329/) (2021)
- [ULIP: Learning a Unified Representation of Language, Images, and Point Clouds for 3D Understanding](https://mlsanity.com/paper/2212.05171/) (2022)
- [SPoT: Better Frozen Model Adaptation through Soft Prompt Transfer](https://mlsanity.com/paper/2110.07904/) (2021)
- [FreeMatch: Self-adaptive Thresholding for Semi-supervised Learning](https://mlsanity.com/paper/2205.07246/) (2022)
- [CLIP-Driven Universal Model for Organ Segmentation and Tumor Detection](https://mlsanity.com/paper/2301.00785/) (2023)
- [Semi-supervised Medical Image Segmentation through Dual-task Consistency](https://mlsanity.com/paper/2009.04448/) (2020)
- [LinkBERT: Pretraining Language Models with Document Links](https://mlsanity.com/paper/2203.15827/) (2022)
- [Not-so-supervised: a survey of semi-supervised, multi-instance, and transfer learning in medical image analysis](https://mlsanity.com/paper/1804.06353/) (2018)
- [DeepOrgan: Multi-level Deep Convolutional Networks for Automated Pancreas Segmentation](https://mlsanity.com/paper/1506.06448/) (2015)
- [SoftMatch: Addressing the Quantity-Quality Trade-off in Semi-supervised Learning](https://mlsanity.com/paper/2301.10921/) (2023)
- [Bidirectional Copy-Paste for Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2305.00673/) (2023)
- [Mutual Consistency Learning for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2109.09960/) (2021)
- [DoDNet: Learning to segment multi-organ and tumors from multiple partially labeled datasets](https://mlsanity.com/paper/2011.10217/) (2020)
- [Exploring Smoothness and Class-Separation for Semi-supervised Medical Image Segmentation](https://mlsanity.com/paper/2203.01324/) (2022)
- [Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentation](https://mlsanity.com/paper/2207.14191/) (2022)
- [Advancing Radiograph Representation Learning with Masked Record Modeling](https://mlsanity.com/paper/2301.13155/) (2023)
- [Foundation Model for Endoscopy Video Analysis via Large-scale Self-supervised Pre-train](https://mlsanity.com/paper/2306.16741/) (2023)
- [UniMiSS: Universal Medical Self-Supervised Learning via Breaking Dimensionality Barrier](https://mlsanity.com/paper/2112.09356/) (2021)
- [BoostMIS: Boosting Medical Image Semi-supervised Learning with Adaptive Pseudo Labeling and Informative Active Annotation](https://mlsanity.com/paper/2203.02533/) (2022)
- [Semi-Supervised and Unsupervised Deep Visual Learning: A Survey](https://mlsanity.com/paper/2208.11296/) (2022)

## Built on by (most cited first, 12 of 12)

- [Universal and Extensible Language-Vision Models for Organ Segmentation and Tumor Detection from Abdominal Computed Tomography](https://mlsanity.com/paper/2405.18356/) (2024)
- [Co-Seg++: Mutual Prompt-Guided Collaborative Learning for Versatile Medical Segmentation](https://mlsanity.com/paper/2506.17159/) (2025)
- [Integrating Semi-Supervised and Active Learning for Semantic Segmentation](https://mlsanity.com/paper/2501.19227/) (2025)
- [ERSR: An Ellipse-constrained pseudo-label refinement and symmetric regularization framework for semi-supervised fetal head segmentation in ultrasound images](https://mlsanity.com/paper/2508.19815/) (2025)
- [ERANet: Edge Replacement Augmentation for Semi-Supervised Meniscus Segmentation with Prototype Consistency Alignment and Conditional Self-Training](https://mlsanity.com/paper/2502.07331/) (2025)
- [Scale-aware Adaptive Supervised Network with Limited Medical Annotations](https://mlsanity.com/paper/2601.01005/) (2026)
- [Colon-Bench: An Agentic Workflow for Scalable Dense Lesion Annotation in Full-Procedure Colonoscopy Videos](https://mlsanity.com/paper/2603.25645/) (2026)
- [SWDL: Stratum-Wise Difference Learning with Deep Laplacian Pyramid for Semi-Supervised 3D Intracranial Hemorrhage Segmentation](https://mlsanity.com/paper/2506.10325/) (2025)
- [SPARSE Data, Rich Results: Few-Shot Semi-Supervised Learning via Class-Conditioned Image Translation](https://mlsanity.com/paper/2508.06429/) (2025)
- [StomataSeg: Semi-Supervised Instance Segmentation for Sorghum Stomatal Components](https://mlsanity.com/paper/2602.00703/) (2026)
- [BCMDA: Bidirectional Correlation Maps Domain Adaptation for Mixed Domain Semi-Supervised Medical Image Segmentation](https://mlsanity.com/paper/2603.24691/) (2026)
- [Are We Overconfident in Models and Results for Semi-Supervised 3D Medical Image Segmentation?](https://mlsanity.com/paper/2605.25561/) (2026)

## Abstract (arXiv)

Annotation scarcity has become a major obstacle for training powerful deep-learning models for medical image segmentation, restricting their deployment in clinical scenarios. To address it, semi-supervised learning by exploiting abundant unlabeled data is highly desirable to boost the model training. However, most existing works still focus on limited medical tasks and underestimate the potential of learning across diverse tasks and multiple datasets. Therefore, in this paper, we introduce a Versatile Semi-supervised framework (VerSemi) to point out a new perspective that integrates various tasks into a unified model with a broad label space, to exploit more unlabeled data for semi-supervised medical image segmentation. Specifically, we introduce a dynamic task-prompted design to segment various targets from different datasets. Next, this unified model is used to identify the foreground regions from all labeled data, to capture cross-dataset semantics. Particularly, we create a synthetic task with a cutmix strategy to augment foreground targets within the expanded label space. To effectively utilize unlabeled data, we introduce a consistency constraint. This involves aligning aggregated predictions from various tasks with those from the synthetic task, further guiding the model in accurately segmenting foreground regions during training. We evaluated our VerSemi model on four public benchmarking datasets. Extensive experiments demonstrated that VerSemi can consistently outperform the second-best method by a large margin (e.g., an average 2.69% Dice gain on four datasets), setting new SOTA performance for semi-supervised medical image segmentation. The code will be released.
