# Uncertainty quantification for noisy inputs-outputs in physics-informed neural networks and neural operators

arXiv: https://arxiv.org/abs/2311.11262 · HTML: https://mlsanity.com/paper/2311.11262/

## Key facts

- Cited by 28 papers in the map (data through 14 Oct 2026).
- Builds on 30 of its 52 references that are in the map.
- First posted on arXiv 19 Nov 2023.

## Builds on (most cited first, 30 of 30)

- [Fourier Neural Operator for Parametric Partial Differential Equations](https://mlsanity.com/paper/2010.08895/) (2020)
- [DeepONet: Learning nonlinear operators for identifying differential equations based on the universal approximation theorem of operators](https://mlsanity.com/paper/1910.03193/) (2019)
- [DGM: A deep learning algorithm for solving partial differential equations](https://mlsanity.com/paper/1708.07469/) (2017)
- [DeepXDE: A deep learning library for solving differential equations](https://mlsanity.com/paper/1907.04502/) (2019)
- [Learning the solution operator of parametric partial differential equations with physics-informed DeepOnets](https://mlsanity.com/paper/2103.10974/) (2021)
- [Physics-Informed Neural Operator for Learning Partial Differential Equations](https://mlsanity.com/paper/2111.03794/) (2021)
- [B-PINNs: Bayesian Physics-Informed Neural Networks for Forward and Inverse PDE Problems with Noisy Data](https://mlsanity.com/paper/2003.06097/) (2020)
- [MIONet: Learning multiple-input operators via tensor product](https://mlsanity.com/paper/2202.06137/) (2022)
- [Uncertainty Quantification in Scientific Machine Learning: Methods, Metrics, and Comparisons](https://mlsanity.com/paper/2201.07766/) (2022)
- [Physics-informed learning of governing equations from scarce data](https://mlsanity.com/paper/2005.03448/) (2020)
- [Quantifying total uncertainty in physics-informed neural networks for solving forward and inverse stochastic problems](https://mlsanity.com/paper/1809.08327/) (2018)
- [Physics-Informed Generative Adversarial Networks for Stochastic Differential Equations](https://mlsanity.com/paper/1811.02033/) (2018)
- [DAS-PINNs: A deep adaptive sampling method for solving high-dimensional partial differential equations](https://mlsanity.com/paper/2112.14038/) (2021)
- [Convergence Rates for Learning Linear Operators from Noisy Data](https://mlsanity.com/paper/2108.12515/) (2021)
- [Bayesian Physics-Informed Neural Networks for real-world nonlinear dynamical systems](https://mlsanity.com/paper/2205.08304/) (2022)
- [Scalable Uncertainty Quantification for Deep Operator Networks using Randomized Priors](https://mlsanity.com/paper/2203.03048/) (2022)
- [Learning Functional Priors and Posteriors from Data and Physics](https://mlsanity.com/paper/2106.05863/) (2021)
- [NeuralUQ: A comprehensive library for uncertainty quantification in neural differential equations and operators](https://mlsanity.com/paper/2208.11866/) (2022)
- [Correcting model misspecification in physics-informed neural networks (PINNs)](https://mlsanity.com/paper/2310.10776/) (2023)
- [DeepONet-Grid-UQ: A Trustworthy Deep Operator Framework for Predicting the Power Grid's Post-Fault Trajectories](https://mlsanity.com/paper/2202.07176/) (2022)
- [L-HYDRA: Multi-Head Physics-Informed Neural Networks](https://mlsanity.com/paper/2301.02152/) (2023)
- [Discovering a reaction-diffusion model for Alzheimer's disease by combining PINNs with symbolic regression](https://mlsanity.com/paper/2307.08107/) (2023)
- [Accelerated replica exchange stochastic gradient Langevin diffusion enhanced Bayesian DeepONet for solving noisy parametric PDEs](https://mlsanity.com/paper/2111.02484/) (2021)
- [Adversarial Adaptive Sampling: Unify PINN and Optimal Transport for the Approximation of PDEs](https://mlsanity.com/paper/2305.18702/) (2023)
- [Multi-Output Physics-Informed Neural Networks for Forward and Inverse PDE Problems with Uncertainties](https://mlsanity.com/paper/2202.01710/) (2022)
- [Variational Bayes Deep Operator Network: A data-driven Bayesian solver for parametric differential equations](https://mlsanity.com/paper/2206.05655/) (2022)
- [A Generative Modeling Framework for Inferring Families of Biomechanical Constitutive Laws in Data-Sparse Regimes](https://mlsanity.com/paper/2305.03184/) (2023)
- [Leveraging Hamilton-Jacobi PDEs with time-dependent Hamiltonians for continual scientific machine learning](https://mlsanity.com/paper/2311.07790/) (2023)
- [Leveraging Multi-time Hamilton-Jacobi PDEs for Certain Scientific Machine Learning Problems](https://mlsanity.com/paper/2303.12928/) (2023)
- [Error-in-variables modelling for operator learning](https://mlsanity.com/paper/2204.10909/) (2022)

## Built on by (most cited first, 28 of 28)

- [A comprehensive and FAIR comparison between MLP and KAN representations for differential equations and operator networks](https://mlsanity.com/paper/2406.02917/) (2024)
- [From PINNs to PIKANs: Recent Advances in Physics-Informed Machine Learning](https://mlsanity.com/paper/2410.13228/) (2024)
- [Calibrated Uncertainty Quantification for Operator Learning via Conformal Prediction](https://mlsanity.com/paper/2402.01960/) (2024)
- [Operator Learning: A Statistical Perspective](https://mlsanity.com/paper/2504.03503/) (2025)
- [Using Uncertainty Quantification to Characterize and Improve Out-of-Domain Learning for PDEs](https://mlsanity.com/paper/2403.10642/) (2024)
- [Leveraging viscous Hamilton-Jacobi PDEs for uncertainty quantification in scientific machine learning](https://mlsanity.com/paper/2404.08809/) (2024)
- [Fast meta-solvers for 3D complex-shape scatterers using neural operators trained on a non-scattering problem](https://mlsanity.com/paper/2405.12380/) (2024)
- [Epistemic Artificial Intelligence is Essential for Machine Learning Models to Truly 'Know When They Do Not Know'](https://mlsanity.com/paper/2505.04950/) (2025)
- [NeuroSEM: A hybrid framework for simulating multiphysics problems by coupling PINNs and spectral elements](https://mlsanity.com/paper/2407.21217/) (2024)
- [Advancing Generalization in PINNs through Latent-Space Representations](https://mlsanity.com/paper/2411.19125/) (2024)
- [Uncertainty quantification for deeponets with ensemble kalman inversion](https://mlsanity.com/paper/2403.03444/) (2024)
- [Split Conformal Prediction in the Function Space with Neural Operators](https://mlsanity.com/paper/2509.04623/) (2025)
- [Uncertainty Quantification in PINNs for Turbulent Flows: Bayesian Inference and Repulsive Ensembles](https://mlsanity.com/paper/2604.17156/) (2026)
- [Quantification of total uncertainty in the physics-informed reconstruction of CVSim-6 physiology](https://mlsanity.com/paper/2408.07201/) (2024)
- [Improved Uncertainty Quantification in Physics-Informed Neural Networks Using Error Bounds and Solution Bundles](https://mlsanity.com/paper/2505.06459/) (2025)
- [Bilevel optimization for learning hyperparameters: Application to solving PDEs and inverse problems with Gaussian processes](https://mlsanity.com/paper/2510.05568/) (2025)
- [Large language models, physics-based modeling, experimental measurements: the trinity of data-scarce learning of polymer properties](https://mlsanity.com/paper/2407.02770/) (2024)
- [HJ-sampler: A Bayesian sampler for inverse problems of a stochastic process by leveraging Hamilton-Jacobi PDEs and score-based generative models](https://mlsanity.com/paper/2409.09614/) (2024)
- [Physics-informed deep learning for infectious disease forecasting](https://mlsanity.com/paper/2501.09298/) (2025)
- [Uncertainty Quantification for Physics-Informed Neural Networks with Extended Fiducial Inference](https://mlsanity.com/paper/2505.19136/) (2025)
- [Noisy PDE Training Requires Bigger PINNs](https://mlsanity.com/paper/2507.06967/) (2025)
- [Data Denoising and Derivative Estimation for Data-Driven Modeling of Nonlinear Dynamical Systems](https://mlsanity.com/paper/2509.14219/) (2025)
- [Harnessing AI for Inverse Partial Differential Equation Problems: Past, Present, and Prospects](https://mlsanity.com/paper/2605.16966/) (2026)
- [Multi-Fidelity Physics-Informed Neural Networks with Bayesian Uncertainty Quantification and Adaptive Residual Learning for Efficient Solution of Parametric Partial Differential Equations](https://mlsanity.com/paper/2602.01176/) (2026)
- [Operator-Informed Gaussian Processes for Complex Helmholtz Wavefields: From Synthetic Benchmarks to In Vivo Brain Elastography](https://mlsanity.com/paper/2607.14193/) (2026)
- [Structure-preserving uncertainty quantification for GENERIC dynamics](https://mlsanity.com/paper/2608.12624/) (2026)
- [Uncertainty propagation in auto-regressive random neural network models](https://mlsanity.com/paper/2608.20483/) (2026)
- [Local gradient neural operator](https://mlsanity.com/paper/2609.07752/) (2026)

## Abstract (arXiv)

Uncertainty quantification (UQ) in scientific machine learning (SciML) becomes increasingly critical as neural networks (NNs) are being widely adopted in addressing complex problems across various scientific disciplines. Representative SciML models are physics-informed neural networks (PINNs) and neural operators (NOs). While UQ in SciML has been increasingly investigated in recent years, very few works have focused on addressing the uncertainty caused by the noisy inputs, such as spatial-temporal coordinates in PINNs and input functions in NOs. The presence of noise in the inputs of the models can pose significantly more challenges compared to noise in the outputs of the models, primarily due to the inherent nonlinearity of most SciML algorithms. As a result, UQ for noisy inputs becomes a crucial factor for reliable and trustworthy deployment of these models in applications involving physical knowledge. To this end, we introduce a Bayesian approach to quantify uncertainty arising from noisy inputs-outputs in PINNs and NOs. We show that this approach can be seamlessly integrated into PINNs and NOs, when they are employed to encode the physical information. PINNs incorporate physics by including physics-informed terms via automatic differentiation, either in the loss function or the likelihood, and often take as input the spatial-temporal coordinate. Therefore, the present method equips PINNs with the capability to address problems where the observed coordinate is subject to noise. On the other hand, pretrained NOs are also commonly employed as equation-free surrogates in solving differential equations and Bayesian inverse problems, in which they take functions as inputs. The proposed approach enables them to handle noisy measurements for both input and output functions with UQ.