# An introduction to reinforcement learning for neuroscience

arXiv: https://arxiv.org/abs/2311.07315 · HTML: https://mlsanity.com/paper/2311.07315/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 26 of its 135 references that are in the map.
- First posted on arXiv 13 Nov 2023.

## Builds on (most cited first, 26 of 26)

- [Model-Agnostic Meta-Learning for Fast Adaptation of Deep Networks](https://mlsanity.com/paper/1703.03400/) (2017)
- [Continuous control with deep reinforcement learning](https://mlsanity.com/paper/1509.02971/) (2015)
- [Playing Atari with Deep Reinforcement Learning](https://mlsanity.com/paper/1312.5602/) (2013)
- [Offline Reinforcement Learning: Tutorial, Review, and Perspectives on Open Problems](https://mlsanity.com/paper/2005.01643/) (2020)
- [Deep Reinforcement Learning with Double Q-learning](https://mlsanity.com/paper/1509.06461/) (2015)
- [Mastering Atari, Go, Chess and Shogi by Planning with a Learned Model](https://mlsanity.com/paper/1911.08265/) (2019)
- [Soft Actor-Critic Algorithms and Applications](https://mlsanity.com/paper/1812.05905/) (2018)
- [Prioritized Experience Replay](https://mlsanity.com/paper/1511.05952/) (2015)
- [IMPALA: Scalable Distributed Deep-RL with Importance Weighted Actor-Learner Architectures](https://mlsanity.com/paper/1802.01561/) (2018)
- [A Distributional Perspective on Reinforcement Learning](https://mlsanity.com/paper/1707.06887/) (2017)
- [QT-Opt: Scalable Deep Reinforcement Learning for Vision-Based Robotic Manipulation](https://mlsanity.com/paper/1806.10293/) (2018)
- [RL2: Fast Reinforcement Learning via Slow Reinforcement Learning](https://mlsanity.com/paper/1611.02779/) (2016)
- [Reinforcement Learning and Control as Probabilistic Inference: Tutorial and Review](https://mlsanity.com/paper/1805.00909/) (2018)
- [Distributional Reinforcement Learning with Quantile Regression](https://mlsanity.com/paper/1710.10044/) (2017)
- [Reinforcement Learning with Unsupervised Auxiliary Tasks](https://mlsanity.com/paper/1611.05397/) (2016)
- [Learning to reinforcement learn](https://mlsanity.com/paper/1611.05763/) (2016)
- [VariBAD: A Very Good Method for Bayes-Adaptive Deep RL via Meta-Learning](https://mlsanity.com/paper/1910.08348/) (2019)
- [Markerless tracking of user-defined features with deep learning](https://mlsanity.com/paper/1804.03142/) (2018)
- [Statistics and Samples in Distributional Reinforcement Learning](https://mlsanity.com/paper/1902.08102/) (2019)
- [Model-Augmented Actor-Critic: Backpropagating through Paths](https://mlsanity.com/paper/2005.08068/) (2020)
- [Is the Policy Gradient a Gradient?](https://mlsanity.com/paper/1906.07073/) (2019)
- [Deep Reinforcement Learning and its Neuroscientific Implications](https://mlsanity.com/paper/2007.03750/) (2020)
- [Been There, Done That: Meta-Learning with Episodic Recall](https://mlsanity.com/paper/1805.09692/) (2018)
- [Deep neuroethology of a virtual rodent](https://mlsanity.com/paper/1911.09451/) (2019)
- [A neurally plausible model learns successor representations in partially observable environments](https://mlsanity.com/paper/1906.09480/) (2019)
- [Predictive auxiliary objectives in deep RL mimic learning in the brain](https://mlsanity.com/paper/2310.06089/) (2023)

## Abstract (arXiv)

Reinforcement learning (RL) has a rich history in neuroscience, from early work on dopamine as a reward prediction error signal (Schultz et al., 1997) to recent work proposing that the brain could implement a form of 'distributional reinforcement learning' popularized in machine learning (Dabney et al., 2020). There has been a close link between theoretical advances in reinforcement learning and neuroscience experiments throughout this literature, and the theories describing the experimental data have therefore become increasingly complex. Here, we provide an introduction and mathematical background to many of the methods that have been used in systems neroscience. We start with an overview of the RL problem and classical temporal difference algorithms, followed by a discussion of 'model-free', 'model-based', and intermediate RL algorithms. We then introduce deep reinforcement learning and discuss how this framework has led to new insights in neuroscience. This includes a particular focus on meta-reinforcement learning (Wang et al., 2018) and distributional RL (Dabney et al., 2020). Finally, we discuss potential shortcomings of the RL formalism for neuroscience and highlight open questions in the field. Code that implements the methods discussed and generates the figures is also provided.