# Domain Generalization by Learning from Privileged Medical Imaging Information

arXiv: https://arxiv.org/abs/2311.05861 · HTML: https://mlsanity.com/paper/2311.05861/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 21 references that are in the map.
- First posted on arXiv 10 Nov 2023.

## Builds on (most cited first, 9 of 9)

- [Domain-Adversarial Training of Neural Networks](https://mlsanity.com/paper/1505.07818/) (2015)
- [Invariant Risk Minimization](https://mlsanity.com/paper/1907.02893/) (2019)
- [In Search of Lost Domain Generalization](https://mlsanity.com/paper/2007.01434/) (2020)
- [Generalizing to Unseen Domains: A Survey on Domain Generalization](https://mlsanity.com/paper/2103.03097/) (2021)
- [Domain Generalization: A Survey](https://mlsanity.com/paper/2103.02503/) (2021)
- [Gradient Matching for Domain Generalization](https://mlsanity.com/paper/2104.09937/) (2021)
- [SelfReg: Self-supervised Contrastive Regularization for Domain Generalization](https://mlsanity.com/paper/2104.09841/) (2021)
- [Improve Unsupervised Domain Adaptation with Mixup Training](https://mlsanity.com/paper/2001.00677/) (2020)
- [Self-Supervised Learning Across Domains](https://mlsanity.com/paper/2007.12368/) (2020)

## Abstract (arXiv)

Learning the ability to generalize knowledge between similar contexts is particularly important in medical imaging as data distributions can shift substantially from one hospital to another, or even from one machine to another. To strengthen generalization, most state-of-the-art techniques inject knowledge of the data distribution shifts by enforcing constraints on learned features or regularizing parameters. We offer an alternative approach: Learning from Privileged Medical Imaging Information (LPMII). We show that using some privileged information such as tumor shape or location leads to stronger domain generalization ability than current state-of-the-art techniques. This paper demonstrates that by using privileged information to predict the severity of intra-layer retinal fluid in optical coherence tomography scans, the classification accuracy of a deep learning model operating on out-of-distribution data improves from 0.911 to 0.934. This paper provides a strong starting point for using privileged information in other medical problems requiring generalization.