# Robust Source-Free Domain Adaptation for Fundus Image Segmentation

arXiv: https://arxiv.org/abs/2310.16665 · HTML: https://mlsanity.com/paper/2310.16665/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 10 of its 42 references that are in the map.
- First posted on arXiv 25 Oct 2023.

## Builds on (most cited first, 10 of 10)

- [Explaining and Harnessing Adversarial Examples](https://mlsanity.com/paper/1412.6572/) (2014)
- [Towards Deep Learning Models Resistant to Adversarial Attacks](https://mlsanity.com/paper/1706.06083/) (2017)
- [Unsupervised Domain Adaptation by Backpropagation](https://mlsanity.com/paper/1409.7495/) (2014)
- [Theoretically Principled Trade-off between Robustness and Accuracy](https://mlsanity.com/paper/1901.08573/) (2019)
- [Learning Transferable Features with Deep Adaptation Networks](https://mlsanity.com/paper/1502.02791/) (2015)
- [Do We Really Need to Access the Source Data? Source Hypothesis Transfer for Unsupervised Domain Adaptation](https://mlsanity.com/paper/2002.08546/) (2020)
- [Tent: Fully Test-time Adaptation by Entropy Minimization](https://mlsanity.com/paper/2006.10726/) (2020)
- [Adversarially robust transfer learning](https://mlsanity.com/paper/1905.08232/) (2019)
- [Generalized but not Robust? Comparing the Effects of Data Modification Methods on Out-of-Domain Generalization and Adversarial Robustness](https://mlsanity.com/paper/2203.07653/) (2022)
- [Target and Task specific Source-Free Domain Adaptive Image Segmentation](https://mlsanity.com/paper/2203.15792/) (2022)

## Abstract (arXiv)

Unsupervised Domain Adaptation (UDA) is a learning technique that transfers knowledge learned in the source domain from labelled training data to the target domain with only unlabelled data. It is of significant importance to medical image segmentation because of the usual lack of labelled training data. Although extensive efforts have been made to optimize UDA techniques to improve the accuracy of segmentation models in the target domain, few studies have addressed the robustness of these models under UDA. In this study, we propose a two-stage training strategy for robust domain adaptation. In the source training stage, we utilize adversarial sample augmentation to enhance the robustness and generalization capability of the source model. And in the target training stage, we propose a novel robust pseudo-label and pseudo-boundary (PLPB) method, which effectively utilizes unlabeled target data to generate pseudo labels and pseudo boundaries that enable model self-adaptation without requiring source data. Extensive experimental results on cross-domain fundus image segmentation confirm the effectiveness and versatility of our method. Source code of this study is openly accessible at https://github.com/LinGrayy/PLPB.
