# Sensitivity-Aware Amortized Bayesian Inference

arXiv: https://arxiv.org/abs/2310.11122 · HTML: https://mlsanity.com/paper/2310.11122/

## Key facts

- Cited by 20 papers in the map (data through 14 Oct 2026).
- Builds on 59 of its 117 references that are in the map.
- First posted on arXiv 17 Oct 2023.

## Builds on (most cited first, 30 of 59)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [Explaining and Harnessing Adversarial Examples](https://mlsanity.com/paper/1412.6572/) (2014)
- [On Calibration of Modern Neural Networks](https://mlsanity.com/paper/1706.04599/) (2017)
- [Simple and Scalable Predictive Uncertainty Estimation using Deep Ensembles](https://mlsanity.com/paper/1612.01474/) (2016)
- [Deep Sets](https://mlsanity.com/paper/1703.06114/) (2017)
- [A Comprehensive Survey on Transfer Learning](https://mlsanity.com/paper/1911.02685/) (2019)
- [The frontier of simulation-based inference](https://mlsanity.com/paper/1911.01429/) (2019)
- [Bayesian Deep Learning and a Probabilistic Perspective of Generalization](https://mlsanity.com/paper/2002.08791/) (2020)
- [Deep Ensembles: A Loss Landscape Perspective](https://mlsanity.com/paper/1912.02757/) (2019)
- [Towards Out-Of-Distribution Generalization: A Survey](https://mlsanity.com/paper/2108.13624/) (2021)
- [What Are Bayesian Neural Network Posteriors Really Like?](https://mlsanity.com/paper/2104.14421/) (2021)
- [A Little Is Enough: Circumventing Defenses For Distributed Learning](https://mlsanity.com/paper/1902.06156/) (2019)
- [OpenOOD: Benchmarking Generalized Out-of-Distribution Detection](https://mlsanity.com/paper/2210.07242/) (2022)
- [Automatic Posterior Transformation for Likelihood-Free Inference](https://mlsanity.com/paper/1905.07488/) (2019)
- [Hyperparameter Ensembles for Robustness and Uncertainty Quantification](https://mlsanity.com/paper/2006.13570/) (2020)
- [BayesFlow: Learning complex stochastic models with invertible neural networks](https://mlsanity.com/paper/2003.06281/) (2020)
- [Validating Bayesian Inference Algorithms with Simulation-Based Calibration](https://mlsanity.com/paper/1804.06788/) (2018)
- [Practical Bayesian model evaluation using leave-one-out cross-validation and WAIC](https://mlsanity.com/paper/1507.04544/) (2015)
- [Real-time gravitational-wave science with neural posterior estimation](https://mlsanity.com/paper/2106.12594/) (2021)
- [Density of States Estimation for Out-of-Distribution Detection](https://mlsanity.com/paper/2006.09273/) (2020)
- [Neural Approximate Sufficient Statistics for Implicit Models](https://mlsanity.com/paper/2010.10079/) (2020)
- [A Swiss Army Infinitesimal Jackknife](https://mlsanity.com/paper/1806.00550/) (2018)
- [Understanding predictive information criteria for Bayesian models](https://mlsanity.com/paper/1307.5928/) (2013)
- [Bayesian Workflow](https://mlsanity.com/paper/2011.01808/) (2020)
- [Detecting Model Misspecification in Amortized Bayesian Inference with Neural Networks](https://mlsanity.com/paper/2112.08866/) (2021)
- [Learning Robust Statistics for Simulation-based Inference under Model Misspecification](https://mlsanity.com/paper/2305.15871/) (2023)
- [Robust Neural Posterior Estimation and Statistical Model Criticism](https://mlsanity.com/paper/2210.06564/) (2022)
- [Investigating the Impact of Model Misspecification in Neural Simulation-based Inference](https://mlsanity.com/paper/2209.01845/) (2022)
- [Variational methods for simulation-based inference](https://mlsanity.com/paper/2203.04176/) (2022)
- [Pareto Smoothed Importance Sampling](https://mlsanity.com/paper/1507.02646/) (2015)

## Built on by (most cited first, 20 of 20)

- [All-in-one simulation-based inference](https://mlsanity.com/paper/2404.09636/) (2024)
- [Simulation-Based Inference: A Practical Guide](https://mlsanity.com/paper/2508.12939/) (2025)
- [Amortized Probabilistic Conditioning for Optimization, Simulation and Inference](https://mlsanity.com/paper/2410.15320/) (2024)
- [Distribution Transformers: Fast Approximate Bayesian Inference With On-The-Fly Prior Adaptation](https://mlsanity.com/paper/2502.02463/) (2025)
- [Robust Amortized Bayesian Inference with Self-Consistency Losses on Unlabeled Data](https://mlsanity.com/paper/2501.13483/) (2025)
- [Does Unsupervised Domain Adaptation Improve the Robustness of Amortized Bayesian Inference? A Systematic Evaluation](https://mlsanity.com/paper/2502.04949/) (2025)
- [BayesFlow 2: Multi-Backend Amortized Bayesian Inference in Python](https://mlsanity.com/paper/2602.07098/) (2026)
- [Improving the Accuracy of Amortized Model Comparison with Self-Consistency](https://mlsanity.com/paper/2508.20614/) (2025)
- [Efficient Autoregressive Inference for Transformer Probabilistic Models](https://mlsanity.com/paper/2510.09477/) (2025)
- [Amortized Bayesian Workflow](https://mlsanity.com/paper/2409.04332/) (2024)
- [Amortized Bayesian Mixture Models](https://mlsanity.com/paper/2501.10229/) (2025)
- [Meta-Statistical Learning: Supervised Learning of Statistical Estimators](https://mlsanity.com/paper/2502.12088/) (2025)
- [PriorGuide: Test-Time Prior Adaptation for Simulation-Based Inference](https://mlsanity.com/paper/2510.13763/) (2025)
- [Amortized Simulation-Based Inference in Generalized Bayes via Neural Posterior Estimation](https://mlsanity.com/paper/2601.22367/) (2026)
- [MIST: Mutual Information Estimation Via Supervised Training](https://mlsanity.com/paper/2511.18945/) (2025)
- [A Review of Diffusion-based Simulation-Based Inference: Foundations and Applications in Non-Ideal Data Scenarios](https://mlsanity.com/paper/2512.23748/) (2025)
- [Guidance for Prior Change via Density Ratio Estimation](https://mlsanity.com/paper/2608.21729/) (2026)
- [Unsupervised Continual Learning for Amortized Bayesian Inference](https://mlsanity.com/paper/2602.22884/) (2026)
- [Overcoming Selection Bias in Statistical Studies With Amortized Bayesian Inference](https://mlsanity.com/paper/2604.18319/) (2026)
- [Amortized Factor Inference Networks for Posterior Inference](https://mlsanity.com/paper/2605.26419/) (2026)

## Abstract (arXiv)

Sensitivity analyses reveal the influence of various modeling choices on the outcomes of statistical analyses. While theoretically appealing, they are overwhelmingly inefficient for complex Bayesian models. In this work, we propose sensitivity-aware amortized Bayesian inference (SA-ABI), a multifaceted approach to efficiently integrate sensitivity analyses into simulation-based inference with neural networks. First, we utilize weight sharing to encode the structural similarities between alternative likelihood and prior specifications in the training process with minimal computational overhead. Second, we leverage the rapid inference of neural networks to assess sensitivity to data perturbations and preprocessing steps. In contrast to most other Bayesian approaches, both steps circumvent the costly bottleneck of refitting the model for each choice of likelihood, prior, or data set. Finally, we propose to use deep ensembles to detect sensitivity arising from unreliable approximation (e.g., due to model misspecification). We demonstrate the effectiveness of our method in applied modeling problems, ranging from disease outbreak dynamics and global warming thresholds to human decision-making. Our results support sensitivity-aware inference as a default choice for amortized Bayesian workflows, automatically providing modelers with insights into otherwise hidden dimensions.
