# Multi-domain improves out-of-distribution and data-limited scenarios for medical image analysis

arXiv: https://arxiv.org/abs/2310.06737 · HTML: https://mlsanity.com/paper/2310.06737/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 51 of its 76 references that are in the map.
- First posted on arXiv 10 Oct 2023.

## Builds on (most cited first, 30 of 51)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [LLaMA: Open and Efficient Foundation Language Models](https://mlsanity.com/paper/2302.13971/) (2023)
- [RoBERTa: A Robustly Optimized BERT Pretraining Approach](https://mlsanity.com/paper/1907.11692/) (2019)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [BioBERT: a pre-trained biomedical language representation model for biomedical text mining](https://mlsanity.com/paper/1901.08746/) (2019)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [CheXpert: A Large Chest Radiograph Dataset with Uncertainty Labels and Expert Comparison](https://mlsanity.com/paper/1901.07031/) (2019)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [Designing Network Design Spaces](https://mlsanity.com/paper/2003.13678/) (2020)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [Big Transfer (BiT): General Visual Representation Learning](https://mlsanity.com/paper/1912.11370/) (2019)
- [MedMNIST v2 -- A large-scale lightweight benchmark for 2D and 3D biomedical image classification](https://mlsanity.com/paper/2110.14795/) (2021)
- [Contrastive Learning of Medical Visual Representations from Paired Images and Text](https://mlsanity.com/paper/2010.00747/) (2020)
- [Transformer in Transformer](https://mlsanity.com/paper/2103.00112/) (2021)
- [Learning multiple visual domains with residual adapters](https://mlsanity.com/paper/1705.08045/) (2017)
- [BioGPT: Generative Pre-trained Transformer for Biomedical Text Generation and Mining](https://mlsanity.com/paper/2210.10341/) (2022)
- [Towards Expert-Level Medical Question Answering with Large Language Models](https://mlsanity.com/paper/2305.09617/) (2023)
- [Med-BERT: pre-trained contextualized embeddings on large-scale structured electronic health records for disease prediction](https://mlsanity.com/paper/2005.12833/) (2020)
- [Domain Adaptation for Medical Image Analysis: A Survey](https://mlsanity.com/paper/2102.09508/) (2021)
- [Big Self-Supervised Models Advance Medical Image Classification](https://mlsanity.com/paper/2101.05224/) (2021)
- [Medical Transformer: Gated Axial-Attention for Medical Image Segmentation](https://mlsanity.com/paper/2102.10662/) (2021)
- [Med3D: Transfer Learning for 3D Medical Image Analysis](https://mlsanity.com/paper/1904.00625/) (2019)
- [BEHRT: Transformer for Electronic Health Records](https://mlsanity.com/paper/1907.09538/) (2019)
- [TransFuse: Fusing Transformers and CNNs for Medical Image Segmentation](https://mlsanity.com/paper/2102.08005/) (2021)
- [CoTr: Efficiently Bridging CNN and Transformer for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.03024/) (2021)
- [BiomedGPT: A Generalist Vision-Language Foundation Model for Diverse Biomedical Tasks](https://mlsanity.com/paper/2305.17100/) (2023)

## Built on by (most cited first, 1 of 1)

- [Evaluating Self-Supervised Learning in Medical Imaging: A Benchmark for Robustness, Generalizability, and Multi-Domain Impact](https://mlsanity.com/paper/2412.19124/) (2024)

## Abstract (arXiv)

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit limitations in generalizing to out-of-distribution samples. In this work, we show that employing models that incorporate multiple domains instead of specialized ones significantly alleviates the limitations observed in specialized models. We refer to this approach as multi-domain model and compare its performance to that of specialized models. For this, we introduce the incorporation of diverse medical image domains, including different imaging modalities like X-ray, MRI, CT, and ultrasound images, as well as various viewpoints such as axial, coronal, and sagittal views. Our findings underscore the superior generalization capabilities of multi-domain models, particularly in scenarios characterized by limited data availability and out-of-distribution, frequently encountered in healthcare applications. The integration of diverse data allows multi-domain models to utilize information across domains, enhancing the overall outcomes substantially. To illustrate, for organ recognition, multi-domain model can enhance accuracy by up to 8% compared to conventional specialized models.