# Adapted Large Language Models Can Outperform Medical Experts in Clinical Text Summarization

arXiv: https://arxiv.org/abs/2309.07430 · HTML: https://mlsanity.com/paper/2309.07430/

## Key facts

- Cited by 246 papers in the map (data through 14 Oct 2026).
- Builds on 41 of its 103 references that are in the map.
- First posted on arXiv 14 Sep 2023.

## Builds on (most cited first, 30 of 41)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformer](https://mlsanity.com/paper/1910.10683/) (2019)
- [Llama 2: Open Foundation and Fine-Tuned Chat Models](https://mlsanity.com/paper/2307.09288/) (2023)
- [Judging LLM-as-a-Judge with MT-Bench and Chatbot Arena](https://mlsanity.com/paper/2306.05685/) (2023)
- [BERTScore: Evaluating Text Generation with BERT](https://mlsanity.com/paper/1904.09675/) (2019)
- [PaLM: Scaling Language Modeling with Pathways](https://mlsanity.com/paper/2204.02311/) (2022)
- [Prefix-Tuning: Optimizing Continuous Prompts for Generation](https://mlsanity.com/paper/2101.00190/) (2021)
- [Finetuned Language Models Are Zero-Shot Learners](https://mlsanity.com/paper/2109.01652/) (2021)
- [QLoRA: Efficient Finetuning of Quantized LLMs](https://mlsanity.com/paper/2305.14314/) (2023)
- [Scaling Instruction-Finetuned Language Models](https://mlsanity.com/paper/2210.11416/) (2022)
- [Sparks of Artificial General Intelligence: Early experiments with GPT-4](https://mlsanity.com/paper/2303.12712/) (2023)
- [A Survey of Large Language Models](https://mlsanity.com/paper/2303.18223/) (2023)
- [GPTQ: Accurate Post-Training Quantization for Generative Pre-trained Transformers](https://mlsanity.com/paper/2210.17323/) (2022)
- [Large Language Models Encode Clinical Knowledge](https://mlsanity.com/paper/2212.13138/) (2022)
- [A Survey on Evaluation of Large Language Models](https://mlsanity.com/paper/2307.03109/) (2023)
- [The Flan Collection: Designing Data and Methods for Effective Instruction Tuning](https://mlsanity.com/paper/2301.13688/) (2023)
- [Hyena Hierarchy: Towards Larger Convolutional Language Models](https://mlsanity.com/paper/2302.10866/) (2023)
- [UL2: Unifying Language Learning Paradigms](https://mlsanity.com/paper/2205.05131/) (2022)
- [Towards Generalist Biomedical AI](https://mlsanity.com/paper/2307.14334/) (2023)
- [MedAlpaca -- An Open-Source Collection of Medical Conversational AI Models and Training Data](https://mlsanity.com/paper/2304.08247/) (2023)
- [Can language models learn from explanations in context?](https://mlsanity.com/paper/2204.02329/) (2022)
- [LongNet: Scaling Transformers to 1,000,000,000 Tokens](https://mlsanity.com/paper/2307.02486/) (2023)
- [Exploring the Limits of Language Modeling](https://mlsanity.com/paper/1602.02410/) (2016)
- [ACI-BENCH: a Novel Ambient Clinical Intelligence Dataset for Benchmarking Automatic Visit Note Generation](https://mlsanity.com/paper/2306.02022/) (2023)
- [The Best of Both Worlds: Combining Recent Advances in Neural Machine Translation](https://mlsanity.com/paper/1804.09849/) (2018)
- [Do We Still Need Clinical Language Models?](https://mlsanity.com/paper/2302.08091/) (2023)
- [Interactive and Visual Prompt Engineering for Ad-hoc Task Adaptation with Large Language Models](https://mlsanity.com/paper/2208.07852/) (2022)
- [An Iterative Optimizing Framework for Radiology Report Summarization with ChatGPT](https://mlsanity.com/paper/2304.08448/) (2023)
- [MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Records](https://mlsanity.com/paper/2308.14089/) (2023)

## Built on by (most cited first, 30 of 246)

- [GPT-4o System Card](https://mlsanity.com/paper/2410.21276/) (2024)
- [MDAgents: An Adaptive Collaboration of LLMs for Medical Decision-Making](https://mlsanity.com/paper/2404.15155/) (2024)
- [ChemLLM: A Chemical Large Language Model](https://mlsanity.com/paper/2402.06852/) (2024)
- [Merlin: A Computed Tomography Vision-Language Foundation Model and Dataset](https://mlsanity.com/paper/2406.06512/) (2024)
- [Delving into LLM-assisted writing in biomedical publications through excess vocabulary](https://mlsanity.com/paper/2406.07016/) (2024)
- [MedCalc-Bench: Evaluating Large Language Models for Medical Calculations](https://mlsanity.com/paper/2406.12036/) (2024)
- [MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks](https://mlsanity.com/paper/2505.23802/) (2025)
- [Improving Retrieval-Augmented Generation in Medicine with Iterative Follow-up Questions](https://mlsanity.com/paper/2408.00727/) (2024)
- [Towards Evaluating and Building Versatile Large Language Models for Medicine](https://mlsanity.com/paper/2408.12547/) (2024)
- [Medical Large Language Model Benchmarks Should Prioritize Construct Validity](https://mlsanity.com/paper/2503.10694/) (2025)
- [Feedback-Guided Extraction of Knowledge Base from Retrieval-Augmented LLM Applications](https://mlsanity.com/paper/2411.14110/) (2024)
- [A Survey of Direct Preference Optimization](https://mlsanity.com/paper/2503.11701/) (2025)
- [A Survey on Medical Large Language Models: Technology, Application, Trustworthiness, and Future Directions](https://mlsanity.com/paper/2406.03712/) (2024)
- [TIMER: Temporal Instruction Modeling and Evaluation for Longitudinal Clinical Records](https://mlsanity.com/paper/2503.04176/) (2025)
- [A Survey of Large Language Model Empowered Agents for Recommendation and Search: Towards Next-Generation Information Retrieval](https://mlsanity.com/paper/2503.05659/) (2025)
- [Towards a Holistic Framework for Multimodal Large Language Models in Three-dimensional Brain CT Report Generation](https://mlsanity.com/paper/2407.02235/) (2024)
- [Generalization Bias in Large Language Model Summarization of Scientific Research](https://mlsanity.com/paper/2504.00025/) (2025)
- [Foundation Models in Radiology: What, How, When, Why and Why Not](https://mlsanity.com/paper/2411.18730/) (2024)
- [A Novel Evaluation Benchmark for Medical LLMs: Illuminating Safety and Effectiveness in Clinical Domains](https://mlsanity.com/paper/2507.23486/) (2025)
- [Large Language Models are Powerful Electronic Health Record Encoders](https://mlsanity.com/paper/2502.17403/) (2025)
- [HealthBench Professional: Evaluating Large Language Models on Real Clinician Chats](https://mlsanity.com/paper/2604.27470/) (2026)
- [MEDIC: Comprehensive Evaluation of Leading Indicators for LLM Safety and Utility in Clinical Applications](https://mlsanity.com/paper/2409.07314/) (2024)
- [Open (Clinical) LLMs are Sensitive to Instruction Phrasings](https://mlsanity.com/paper/2407.09429/) (2024)
- [ColaCare: Enhancing Electronic Health Record Modeling through Large Language Model-Driven Multi-Agent Collaboration](https://mlsanity.com/paper/2410.02551/) (2024)
- [Revisiting Uncertainty Estimation and Calibration of Large Language Models](https://mlsanity.com/paper/2505.23854/) (2025)
- [Unlocking Memorization in Large Language Models with Dynamic Soft Prompting](https://mlsanity.com/paper/2409.13853/) (2024)
- [Can Large Language Models abstract Medical Coded Language?](https://mlsanity.com/paper/2403.10822/) (2024)
- [SurGen: Text-Guided Diffusion Model for Surgical Video Generation](https://mlsanity.com/paper/2408.14028/) (2024)
- [Overview of the First Shared Task on Clinical Text Generation: RRG24 and "Discharge Me!"](https://mlsanity.com/paper/2409.16603/) (2024)
- [HANNA: Hard-constraint Neural Network for Consistent Activity Coefficient Prediction](https://mlsanity.com/paper/2407.18011/) (2024)

## Abstract (arXiv)

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language processing (NLP), their effectiveness on a diverse range of clinical summarization tasks remains unproven. In this study, we apply adaptation methods to eight LLMs, spanning four distinct clinical summarization tasks: radiology reports, patient questions, progress notes, and doctor-patient dialogue. Quantitative assessments with syntactic, semantic, and conceptual NLP metrics reveal trade-offs between models and adaptation methods. A clinical reader study with ten physicians evaluates summary completeness, correctness, and conciseness; in a majority of cases, summaries from our best adapted LLMs are either equivalent (45%) or superior (36%) compared to summaries from medical experts. The ensuing safety analysis highlights challenges faced by both LLMs and medical experts, as we connect errors to potential medical harm and categorize types of fabricated information. Our research provides evidence of LLMs outperforming medical experts in clinical text summarization across multiple tasks. This suggests that integrating LLMs into clinical workflows could alleviate documentation burden, allowing clinicians to focus more on patient care.