# On the detection of Out-Of-Distribution samples in Multiple Instance Learning

arXiv: https://arxiv.org/abs/2309.05528 · HTML: https://mlsanity.com/paper/2309.05528/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 22 of its 31 references that are in the map.
- First posted on arXiv 11 Sep 2023.

## Builds on (most cited first, 22 of 22)

- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Fashion-MNIST: a Novel Image Dataset for Benchmarking Machine Learning Algorithms](https://mlsanity.com/paper/1708.07747/) (2017)
- [A Baseline for Detecting Misclassified and Out-of-Distribution Examples in Neural Networks](https://mlsanity.com/paper/1610.02136/) (2016)
- [Describing Textures in the Wild](https://mlsanity.com/paper/1311.3618/) (2013)
- [A Simple Unified Framework for Detecting Out-of-Distribution Samples and Adversarial Attacks](https://mlsanity.com/paper/1807.03888/) (2018)
- [WILDS: A Benchmark of in-the-Wild Distribution Shifts](https://mlsanity.com/paper/2012.07421/) (2020)
- [Enhancing The Reliability of Out-of-distribution Image Detection in Neural Networks](https://mlsanity.com/paper/1706.02690/) (2017)
- [Energy-based Out-of-distribution Detection](https://mlsanity.com/paper/2010.03759/) (2020)
- [Attention-based Deep Multiple Instance Learning](https://mlsanity.com/paper/1802.04712/) (2018)
- [Deep Anomaly Detection with Outlier Exposure](https://mlsanity.com/paper/1812.04606/) (2018)
- [Generalized Out-of-Distribution Detection: A Survey](https://mlsanity.com/paper/2110.11334/) (2021)
- [Data Efficient and Weakly Supervised Computational Pathology on Whole Slide Images](https://mlsanity.com/paper/2004.09666/) (2020)
- [Out-of-Distribution Detection with Deep Nearest Neighbors](https://mlsanity.com/paper/2204.06507/) (2022)
- [Scaling Out-of-Distribution Detection for Real-World Settings](https://mlsanity.com/paper/1911.11132/) (2019)
- [Rotation Equivariant CNNs for Digital Pathology](https://mlsanity.com/paper/1806.03962/) (2018)
- [Deep Learning for Classical Japanese Literature](https://mlsanity.com/paper/1812.01718/) (2018)
- [Generalized ODIN: Detecting Out-of-distribution Image without Learning from Out-of-distribution Data](https://mlsanity.com/paper/2002.11297/) (2020)
- [OpenOOD v1.5: Enhanced Benchmark for Out-of-Distribution Detection](https://mlsanity.com/paper/2306.09301/) (2023)
- [DICE: Leveraging Sparsification for Out-of-Distribution Detection](https://mlsanity.com/paper/2111.09805/) (2021)
- [Differentiable Zooming for Multiple Instance Learning on Whole-Slide Images](https://mlsanity.com/paper/2204.12454/) (2022)
- [Probabilistic Attention based on Gaussian Processes for Deep Multiple Instance Learning](https://mlsanity.com/paper/2302.04061/) (2023)
- [Uncertainty-Aware Multiple-Instance Learning for Reliable Classification: Application to Optical Coherence Tomography](https://mlsanity.com/paper/2302.03116/) (2023)

## Abstract (arXiv)

The deployment of machine learning solutions in real-world scenarios often involves addressing the challenge of out-of-distribution (OOD) detection. While significant efforts have been devoted to OOD detection in classical supervised settings, the context of weakly supervised learning, particularly the Multiple Instance Learning (MIL) framework, remains under-explored. In this study, we tackle this challenge by adapting post-hoc OOD detection methods to the MIL setting while introducing a novel benchmark specifically designed to assess OOD detection performance in weakly supervised scenarios. Across extensive experiments based on diverse public datasets, KNN emerges as the best-performing method overall. However, it exhibits significant shortcomings on some datasets, emphasizing the complexity of this under-explored and challenging topic. Our findings shed light on the complex nature of OOD detection under the MIL framework, emphasizing the importance of developing novel, robust, and reliable methods that can generalize effectively in a weakly supervised context. The code for the paper is available here: https://github.com/loic-lb/OOD_MIL.