# Exploring Limits of Diffusion-Synthetic Training with Weakly Supervised Semantic Segmentation

arXiv: https://arxiv.org/abs/2309.01369 · HTML: https://mlsanity.com/paper/2309.01369/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 62 of its 91 references that are in the map.
- First posted on arXiv 4 Sep 2023.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 30 of 62)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [Zero-Shot Text-to-Image Generation](https://mlsanity.com/paper/2102.12092/) (2021)
- [Scaling Up Visual and Vision-Language Representation Learning With Noisy Text Supervision](https://mlsanity.com/paper/2102.05918/) (2021)
- [GLIDE: Towards Photorealistic Image Generation and Editing with Text-Guided Diffusion Models](https://mlsanity.com/paper/2112.10741/) (2021)
- [DreamBooth: Fine Tuning Text-to-Image Diffusion Models for Subject-Driven Generation](https://mlsanity.com/paper/2208.12242/) (2022)
- [Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentation](https://mlsanity.com/paper/1802.02611/) (2018)
- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [Prompt-to-Prompt Image Editing with Cross Attention Control](https://mlsanity.com/paper/2208.01626/) (2022)
- [CLIPScore: A Reference-free Evaluation Metric for Image Captioning](https://mlsanity.com/paper/2104.08718/) (2021)
- [Masked-attention Mask Transformer for Universal Image Segmentation](https://mlsanity.com/paper/2112.01527/) (2021)
- [LAION-400M: Open Dataset of CLIP-Filtered 400 Million Image-Text Pairs](https://mlsanity.com/paper/2111.02114/) (2021)
- [Microsoft COCO Captions: Data Collection and Evaluation Server](https://mlsanity.com/paper/1504.00325/) (2015)
- [Demystifying MMD GANs](https://mlsanity.com/paper/1801.01401/) (2018)
- [CyCADA: Cycle-Consistent Adversarial Domain Adaptation](https://mlsanity.com/paper/1711.03213/) (2017)
- [Playing for Data: Ground Truth from Computer Games](https://mlsanity.com/paper/1608.02192/) (2016)
- [EDA: Easy Data Augmentation Techniques for Boosting Performance on Text Classification Tasks](https://mlsanity.com/paper/1901.11196/) (2019)
- [Extract Free Dense Labels from CLIP](https://mlsanity.com/paper/2112.01071/) (2021)
- [DenseCLIP: Language-Guided Dense Prediction with Context-Aware Prompting](https://mlsanity.com/paper/2112.01518/) (2021)
- [GroupViT: Semantic Segmentation Emerges from Text Supervision](https://mlsanity.com/paper/2202.11094/) (2022)
- [Label-Efficient Semantic Segmentation with Diffusion Models](https://mlsanity.com/paper/2112.03126/) (2021)
- [Open-Vocabulary Panoptic Segmentation with Text-to-Image Diffusion Models](https://mlsanity.com/paper/2303.04803/) (2023)

## Built on by (most cited first, 4 of 4)

- [Follow-Your-Instruction: A Comprehensive MLLM Agent for World Data Synthesis](https://mlsanity.com/paper/2508.05580/) (2025)
- [S3OD: Towards Generalizable Salient Object Detection with Synthetic Data](https://mlsanity.com/paper/2510.21605/) (2025)
- [FA-Seg: A Fast and Accurate Diffusion-Based Method for Open-Vocabulary Segmentation](https://mlsanity.com/paper/2506.23323/) (2025)
- [R&D: Balancing Reliability and Diversity in Synthetic Data Augmentation for Semantic Segmentation](https://mlsanity.com/paper/2603.18427/) (2026)

## Abstract (arXiv)

The advance of generative models for images has inspired various training techniques for image recognition utilizing synthetic images. In semantic segmentation, one promising approach is extracting pseudo-masks from attention maps in text-to-image diffusion models, which enables real-image-and-annotation-free training. However, the pioneering training method using the diffusion-synthetic images and pseudo-masks, i.e., DiffuMask has limitations in terms of mask quality, scalability, and ranges of applicable domains. To overcome these limitations, this work introduces three techniques for diffusion-synthetic semantic segmentation training. First, reliability-aware robust training, originally used in weakly supervised learning, helps segmentation with insufficient synthetic mask quality. %Second, large-scale pretraining of whole segmentation models, not only backbones, on synthetic ImageNet-1k-class images with pixel-labels benefits downstream segmentation tasks. Second, we introduce prompt augmentation, data augmentation to the prompt text set to scale up and diversify training images with a limited text resources. Finally, LoRA-based adaptation of Stable Diffusion enables the transfer to a distant domain, e.g., auto-driving images. Experiments in PASCAL VOC, ImageNet-S, and Cityscapes show that our method effectively closes gap between real and synthetic training in semantic segmentation.