# ADFA: Attention-augmented Differentiable top-k Feature Adaptation for Unsupervised Medical Anomaly Detection

arXiv: https://arxiv.org/abs/2308.15280 · HTML: https://mlsanity.com/paper/2308.15280/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 19 of its 27 references that are in the map.
- First posted on arXiv 29 Aug 2023.

## Builds on (most cited first, 19 of 19)

- [Wide Residual Networks](https://mlsanity.com/paper/1605.07146/) (2016)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [PaDiM: a Patch Distribution Modeling Framework for Anomaly Detection and Localization](https://mlsanity.com/paper/2011.08785/) (2020)
- [ECA-Net: Efficient Channel Attention for Deep Convolutional Neural Networks](https://mlsanity.com/paper/1910.03151/) (2019)
- [Unsupervised Anomaly Detection with Generative Adversarial Networks to Guide Marker Discovery](https://mlsanity.com/paper/1703.05921/) (2017)
- [Anomaly Detection via Reverse Distillation from One-Class Embedding](https://mlsanity.com/paper/2201.10703/) (2022)
- [Uninformed Students: Student-Teacher Anomaly Detection with Discriminative Latent Embeddings](https://mlsanity.com/paper/1911.02357/) (2019)
- [An Intriguing Failing of Convolutional Neural Networks and the CoordConv Solution](https://mlsanity.com/paper/1807.03247/) (2018)
- [Sub-Image Anomaly Detection with Deep Pyramid Correspondences](https://mlsanity.com/paper/2005.02357/) (2020)
- [Multiresolution Knowledge Distillation for Anomaly Detection](https://mlsanity.com/paper/2011.11108/) (2020)
- [Patch SVDD: Patch-level SVDD for Anomaly Detection and Segmentation](https://mlsanity.com/paper/2006.16067/) (2020)
- [Student-Teacher Feature Pyramid Matching for Anomaly Detection](https://mlsanity.com/paper/2103.04257/) (2021)
- [CFA: Coupled-hypersphere-based Feature Adaptation for Target-Oriented Anomaly Localization](https://mlsanity.com/paper/2206.04325/) (2022)
- [Deep Learning for Medical Anomaly Detection -- A Survey](https://mlsanity.com/paper/2012.02364/) (2020)
- [Modeling the Distribution of Normal Data in Pre-Trained Deep Features for Anomaly Detection](https://mlsanity.com/paper/2005.14140/) (2020)
- [Deep Nearest Neighbor Anomaly Detection](https://mlsanity.com/paper/2002.10445/) (2020)
- [COVID-19 Image Data Collection](https://mlsanity.com/paper/2003.11597/) (2020)
- [Unsupervised Lesion Detection via Image Restoration with a Normative Prior](https://mlsanity.com/paper/2005.00031/) (2020)
- [Anomaly Detection in Medical Imaging -- A Mini Review](https://mlsanity.com/paper/2108.11986/) (2021)

## Abstract (arXiv)

The scarcity of annotated data, particularly for rare diseases, limits the variability of training data and the range of detectable lesions, presenting a significant challenge for supervised anomaly detection in medical imaging. To solve this problem, we propose a novel unsupervised method for medical image anomaly detection: Attention-Augmented Differentiable top-k Feature Adaptation (ADFA). The method utilizes Wide-ResNet50-2 (WR50) network pre-trained on ImageNet to extract initial feature representations. To reduce the channel dimensionality while preserving relevant channel information, we employ an attention-augmented patch descriptor on the extracted features. We then apply differentiable top-k feature adaptation to train the patch descriptor, mapping the extracted feature representations to a new vector space, enabling effective detection of anomalies. Experiments show that ADFA outperforms state-of-the-art (SOTA) methods on multiple challenging medical image datasets, confirming its effectiveness in medical anomaly detection.