# Tumor-Centered Patching for Enhanced Medical Image Segmentation

arXiv: https://arxiv.org/abs/2308.12168 · HTML: https://mlsanity.com/paper/2308.12168/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 22 of its 50 references that are in the map.
- First posted on arXiv 23 Aug 2023.

## Builds on (most cited first, 22 of 22)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Fully Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1411.4038/) (2014)
- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [A large annotated medical image dataset for the development and evaluation of segmentation algorithms](https://mlsanity.com/paper/1902.09063/) (2019)
- [CHAOS Challenge -- Combined (CT-MR) Healthy Abdominal Organ Segmentation](https://mlsanity.com/paper/2001.06535/) (2020)
- [Efficient Multi-Scale 3D CNN with Fully Connected CRF for Accurate Brain Lesion Segmentation](https://mlsanity.com/paper/1603.05959/) (2016)
- [Persistence Images: A Stable Vector Representation of Persistent Homology](https://mlsanity.com/paper/1507.06217/) (2015)
- [The KiTS19 Challenge Data: 300 Kidney Tumor Cases with Clinical Context, CT Semantic Segmentations, and Surgical Outcomes](https://mlsanity.com/paper/1904.00445/) (2019)
- [Ensembles of Multiple Models and Architectures for Robust Brain Tumour Segmentation](https://mlsanity.com/paper/1711.01468/) (2017)
- [Brain Tumor Segmentation and Radiomics Survival Prediction: Contribution to the BRATS 2017 Challenge](https://mlsanity.com/paper/1802.10508/) (2018)
- [The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)](https://mlsanity.com/paper/2305.17033/) (2023)
- [Optimized U-Net for Brain Tumor Segmentation](https://mlsanity.com/paper/2110.03352/) (2021)
- [GaNDLF: A Generally Nuanced Deep Learning Framework for Scalable End-to-End Clinical Workflows in Medical Imaging](https://mlsanity.com/paper/2103.01006/) (2021)
- [Cubical Ripser: Software for computing persistent homology of image and volume data](https://mlsanity.com/paper/2005.12692/) (2020)
- [BiTr-Unet: a CNN-Transformer Combined Network for MRI Brain Tumor Segmentation](https://mlsanity.com/paper/2109.12271/) (2021)
- [Dist2Cycle: A Simplicial Neural Network for Homology Localization](https://mlsanity.com/paper/2110.15182/) (2021)
- [Topology-Aware Focal Loss for 3D Image Segmentation](https://mlsanity.com/paper/2304.12223/) (2023)
- [Reciprocal Adversarial Learning for Brain Tumor Segmentation: A Solution to BraTS Challenge 2021 Segmentation Task](https://mlsanity.com/paper/2201.03777/) (2022)
- [Sequential 3D U-Nets for Biologically-Informed Brain Tumor Segmentation](https://mlsanity.com/paper/1709.02967/) (2017)
- [Using Persistent Homology Topological Features to Characterize Medical Images: Case Studies on Lung and Brain Cancers](https://mlsanity.com/paper/2012.12102/) (2020)

## Abstract (arXiv)

The realm of medical image diagnosis has advanced significantly with the integration of computer-aided diagnosis and surgical systems. However, challenges persist, particularly in achieving precise image segmentation. While deep learning techniques show potential, obstacles like limited resources, slow convergence, and class imbalance impede their effectiveness. Traditional patch-based methods, though common, struggle to capture intricate tumor boundaries and often lead to redundant samples, compromising computational efficiency and feature quality. To tackle these issues, this research introduces an innovative approach centered on the tumor itself for patch-based image analysis. This novel tumor-centered patching method aims to address the class imbalance and boundary deficiencies, enabling focused and accurate tumor segmentation. By aligning patches with the tumor's anatomical context, this technique enhances feature extraction accuracy and reduces computational load. Experimental results demonstrate improved class imbalance, with segmentation scores of 0.78, 0.76, and 0.71 for whole, core, and enhancing tumors, respectively using a lightweight simple U-Net. This approach shows potential for enhancing medical image segmentation and improving computer-aided diagnosis systems.