# The TYC Dataset for Understanding Instance-Level Semantics and Motions of Cells in Microstructures

arXiv: https://arxiv.org/abs/2308.12116 · HTML: https://mlsanity.com/paper/2308.12116/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 38 of its 93 references that are in the map.
- First posted on arXiv 23 Aug 2023.

## Builds on (most cited first, 30 of 38)

- [Language Models are Few-Shot Learners](https://mlsanity.com/paper/2005.14165/) (2020)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [ImageNet Large Scale Visual Recognition Challenge](https://mlsanity.com/paper/1409.0575/) (2014)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Masked Autoencoders Are Scalable Vision Learners](https://mlsanity.com/paper/2111.06377/) (2021)
- [Emerging Properties in Self-Supervised Vision Transformers](https://mlsanity.com/paper/2104.14294/) (2021)
- [The Cityscapes Dataset for Semantic Urban Scene Understanding](https://mlsanity.com/paper/1604.01685/) (2016)
- [LAION-5B: An open large-scale dataset for training next generation image-text models](https://mlsanity.com/paper/2210.08402/) (2022)
- [On the Opportunities and Risks of Foundation Models](https://mlsanity.com/paper/2108.07258/) (2021)
- [Pre-train, Prompt, and Predict: A Systematic Survey of Prompting Methods in Natural Language Processing](https://mlsanity.com/paper/2107.13586/) (2021)
- [Ego4D: Around the World in 3,000 Hours of Egocentric Video](https://mlsanity.com/paper/2110.07058/) (2021)
- [Big Self-Supervised Models are Strong Semi-Supervised Learners](https://mlsanity.com/paper/2006.10029/) (2020)
- [Self-Supervised Learning from Images with a Joint-Embedding Predictive Architecture](https://mlsanity.com/paper/2301.08243/) (2023)
- [Scaling Vision Transformers](https://mlsanity.com/paper/2106.04560/) (2021)
- [Panoptic Segmentation](https://mlsanity.com/paper/1801.00868/) (2018)
- [Exploring Plain Vision Transformer Backbones for Object Detection](https://mlsanity.com/paper/2203.16527/) (2022)
- [Deep Visual Domain Adaptation: A Survey](https://mlsanity.com/paper/1802.03601/) (2018)
- [Masked Autoencoders As Spatiotemporal Learners](https://mlsanity.com/paper/2205.09113/) (2022)
- [Video Instance Segmentation](https://mlsanity.com/paper/1905.04804/) (2019)
- [Segment Anything Model for Medical Image Analysis: an Experimental Study](https://mlsanity.com/paper/2304.10517/) (2023)
- [A Brief Review of Domain Adaptation](https://mlsanity.com/paper/2010.03978/) (2020)
- [UnFlow: Unsupervised Learning of Optical Flow with a Bidirectional Census Loss](https://mlsanity.com/paper/1711.07837/) (2017)
- [Cell Detection with Star-convex Polygons](https://mlsanity.com/paper/1806.03535/) (2018)
- [Multiple Object Tracking: A Literature Review](https://mlsanity.com/paper/1409.7618/) (2014)
- [What Matters in Unsupervised Optical Flow](https://mlsanity.com/paper/2006.04902/) (2020)
- [Occlusion Aware Unsupervised Learning of Optical Flow](https://mlsanity.com/paper/1711.05890/) (2017)
- [Deep Visual Domain Adaptation](https://mlsanity.com/paper/2012.14176/) (2020)
- [SAM on Medical Images: A Comprehensive Study on Three Prompt Modes](https://mlsanity.com/paper/2305.00035/) (2023)

## Built on by (most cited first, 2 of 2)

- [A Perspective on Deep Vision Performance with Standard Image and Video Codecs](https://mlsanity.com/paper/2404.12330/) (2024)
- [Generalized Small Object Detection:A Point-Prompted Paradigm and Benchmark](https://mlsanity.com/paper/2604.02773/) (2026)

## Abstract (arXiv)

Segmenting cells and tracking their motion over time is a common task in biomedical applications. However, predicting accurate instance-wise segmentation and cell motions from microscopy imagery remains a challenging task. Using microstructured environments for analyzing single cells in a constant flow of media adds additional complexity. While large-scale labeled microscopy datasets are available, we are not aware of any large-scale dataset, including both cells and microstructures. In this paper, we introduce the trapped yeast cell (TYC) dataset, a novel dataset for understanding instance-level semantics and motions of cells in microstructures. We release 105 dense annotated high-resolution brightfield microscopy images, including about 19k instance masks. We also release 261 curated video clips composed of 1293 high-resolution microscopy images to facilitate unsupervised understanding of cell motions and morphology. TYC offers ten times more instance annotations than the previously largest dataset, including cells and microstructures. Our effort also exceeds previous attempts in terms of microstructure variability, resolution, complexity, and capturing device (microscopy) variability. We facilitate a unified comparison on our novel dataset by introducing a standardized evaluation strategy. TYC and evaluation code are publicly available under CC BY 4.0 license.
