# CARE: A Large Scale CT Image Dataset and Clinical Applicable Benchmark Model for Rectal Cancer Segmentation

arXiv: https://arxiv.org/abs/2308.08283 · HTML: https://mlsanity.com/paper/2308.08283/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Builds on 14 of its 25 references that are in the map.
- First posted on arXiv 16 Aug 2023.

## Builds on (most cited first, 14 of 14)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.12620/) (2023)
- [AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentation](https://mlsanity.com/paper/2206.08023/) (2022)
- [Customized Segment Anything Model for Medical Image Segmentation](https://mlsanity.com/paper/2304.13785/) (2023)
- [UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformer](https://mlsanity.com/paper/2109.04335/) (2021)
- [Polyp-SAM: Transfer SAM for Polyp Segmentation](https://mlsanity.com/paper/2305.00293/) (2023)
- [A Survey on Segment Anything Model (SAM): Vision Foundation Model Meets Prompt Engineering](https://mlsanity.com/paper/2306.06211/) (2023)
- [Focal-UNet: UNet-like Focal Modulation for Medical Image Segmentation](https://mlsanity.com/paper/2212.09263/) (2022)

## Built on by (most cited first, 4 of 4)

- [Meply: A Large-scale Dataset and Baseline Evaluations for Metastatic Perirectal Lymph Node Detection and Segmentation](https://mlsanity.com/paper/2404.08916/) (2024)
- [State of Abdominal CT Datasets: A Critical Review of Bias, Clinical Relevance, and Real-world Applicability](https://mlsanity.com/paper/2508.13626/) (2025)
- [LN-Gen: Rectal Lymph Nodes Generation via Anatomical Features](https://mlsanity.com/paper/2408.14977/) (2024)
- [CAFusion: Controllable Anatomical Synthesis of Perirectal Lymph Nodes via SDF-guided Diffusion](https://mlsanity.com/paper/2503.06919/) (2025)

## Abstract (arXiv)

Rectal cancer segmentation of CT image plays a crucial role in timely clinical diagnosis, radiotherapy treatment, and follow-up. Although current segmentation methods have shown promise in delineating cancerous tissues, they still encounter challenges in achieving high segmentation precision. These obstacles arise from the intricate anatomical structures of the rectum and the difficulties in performing differential diagnosis of rectal cancer. Additionally, a major obstacle is the lack of a large-scale, finely annotated CT image dataset for rectal cancer segmentation. To address these issues, this work introduces a novel large scale rectal cancer CT image dataset CARE with pixel-level annotations for both normal and cancerous rectum, which serves as a valuable resource for algorithm research and clinical application development. Moreover, we propose a novel medical cancer lesion segmentation benchmark model named U-SAM. The model is specifically designed to tackle the challenges posed by the intricate anatomical structures of abdominal organs by incorporating prompt information. U-SAM contains three key components: promptable information (e.g., points) to aid in target area localization, a convolution module for capturing low-level lesion details, and skip-connections to preserve and recover spatial information during the encoding-decoding process. To evaluate the effectiveness of U-SAM, we systematically compare its performance with several popular segmentation methods on the CARE dataset. The generalization of the model is further verified on the WORD dataset. Extensive experiments demonstrate that the proposed U-SAM outperforms state-of-the-art methods on these two datasets. These experiments can serve as the baseline for future research and clinical application development.