# AutoGen: Enabling Next-Gen LLM Applications via Multi-Agent Conversation

arXiv: https://arxiv.org/abs/2308.08155 · HTML: https://mlsanity.com/paper/2308.08155/

## Key facts

- Cited by 1,906 papers in the map (data through 7 Oct 2026).
- Placed in Software engineering coding agents, one of 16 directions in LLM agents and tool use.
- Builds on 28 of its 75 references that are in the map.
- First posted on arXiv 16 Aug 2023.

## Placed in

- LLM agents and tool use / [Software engineering coding agents](https://mlsanity.com/agents/software-engineering-coding-agents/)

## Builds on (most cited first, 28 of 28)

- [Retrieval-Augmented Generation for Knowledge-Intensive NLP Tasks](https://mlsanity.com/paper/2005.11401/) (2020)
- [Sentence-BERT: Sentence Embeddings using Siamese BERT-Networks](https://mlsanity.com/paper/1908.10084/) (2019)
- [ReAct: Synergizing Reasoning and Acting in Language Models](https://mlsanity.com/paper/2210.03629/) (2022)
- [Measuring Mathematical Problem Solving With the MATH Dataset](https://mlsanity.com/paper/2103.03874/) (2021)
- [Reflexion: Language Agents with Verbal Reinforcement Learning](https://mlsanity.com/paper/2303.11366/) (2023)
- [Generative Agents: Interactive Simulacra of Human Behavior](https://mlsanity.com/paper/2304.03442/) (2023)
- [Playing Atari with Deep Reinforcement Learning](https://mlsanity.com/paper/1312.5602/) (2013)
- [Voyager: An Open-Ended Embodied Agent with Large Language Models](https://mlsanity.com/paper/2305.16291/) (2023)
- [WebArena: A Realistic Web Environment for Building Autonomous Agents](https://mlsanity.com/paper/2307.13854/) (2023)
- [MetaGPT: Meta Programming for A Multi-Agent Collaborative Framework](https://mlsanity.com/paper/2308.00352/) (2023)
- [Improving Factuality and Reasoning in Language Models through Multiagent Debate](https://mlsanity.com/paper/2305.14325/) (2023)
- [Concrete Problems in AI Safety](https://mlsanity.com/paper/1606.06565/) (2016)
- [Gorilla: Large Language Model Connected with Massive APIs](https://mlsanity.com/paper/2305.15334/) (2023)
- [ALFWorld: Aligning Text and Embodied Environments for Interactive Learning](https://mlsanity.com/paper/2010.03768/) (2020)
- [Encouraging Divergent Thinking in Large Language Models through Multi-Agent Debate](https://mlsanity.com/paper/2305.19118/) (2023)
- [VirtualHome: Simulating Household Activities via Programs](https://mlsanity.com/paper/1806.07011/) (2018)
- [Language Models can Solve Computer Tasks](https://mlsanity.com/paper/2303.17491/) (2023)
- [Large Language Models as Tool Makers](https://mlsanity.com/paper/2305.17126/) (2023)
- [Reinforcement Learning on Web Interfaces Using Workflow-Guided Exploration](https://mlsanity.com/paper/1802.08802/) (2018)
- [StarCraft II: A New Challenge for Reinforcement Learning](https://mlsanity.com/paper/1708.04782/) (2017)
- [Self-collaboration Code Generation via ChatGPT](https://mlsanity.com/paper/2304.07590/) (2023)
- [Deal or No Deal? End-to-End Learning for Negotiation Dialogues](https://mlsanity.com/paper/1706.05125/) (2017)
- [iGibson 1.0: a Simulation Environment for Interactive Tasks in Large Realistic Scenes](https://mlsanity.com/paper/2012.02924/) (2020)
- [Evaluating Correctness and Faithfulness of Instruction-Following Models for Question Answering](https://mlsanity.com/paper/2307.16877/) (2023)
- [Retrieval Augmented Code Generation and Summarization](https://mlsanity.com/paper/2108.11601/) (2021)
- [FLAML: A Fast and Lightweight AutoML Library](https://mlsanity.com/paper/1911.04706/) (2019)
- [LIDA: A Tool for Automatic Generation of Grammar-Agnostic Visualizations and Infographics using Large Language Models](https://mlsanity.com/paper/2303.02927/) (2023)
- [Large Language Models for Supply Chain Optimization](https://mlsanity.com/paper/2307.03875/) (2023)

## Built on by (most cited first, 30 of 1906)

- [A Survey on Large Language Model based Autonomous Agents](https://mlsanity.com/paper/2308.11432/) (2023)
- [The Rise and Potential of Large Language Model Based Agents: A Survey](https://mlsanity.com/paper/2309.07864/) (2023)
- [AlphaEvolve: A coding agent for scientific and algorithmic discovery](https://mlsanity.com/paper/2506.13131/) (2025)
- [Why Do Multi-Agent LLM Systems Fail?](https://mlsanity.com/paper/2503.13657/) (2025)
- [Multi-Agent Collaboration Mechanisms: A Survey of LLMs](https://mlsanity.com/paper/2501.06322/) (2025)
- [Agent Laboratory: Using LLM Agents as Research Assistants](https://mlsanity.com/paper/2501.04227/) (2025)
- [LLMs Get Lost In Multi-Turn Conversation](https://mlsanity.com/paper/2505.06120/) (2025)
- [Personal LLM Agents: Insights and Survey about the Capability, Efficiency and Security](https://mlsanity.com/paper/2401.05459/) (2024)
- [SkillRL: Evolving Agents via Recursive Skill-Augmented Reinforcement Learning](https://mlsanity.com/paper/2602.08234/) (2026)
- [Large Language Model Agent: A Survey on Methodology, Applications and Challenges](https://mlsanity.com/paper/2503.21460/) (2025)
- [Mobile-Agent-v2: Mobile Device Operation Assistant with Effective Navigation via Multi-Agent Collaboration](https://mlsanity.com/paper/2406.01014/) (2024)
- [AI Agents vs. Agentic AI: A Conceptual Taxonomy, Applications and Challenges](https://mlsanity.com/paper/2505.10468/) (2025)
- [MAC-SQL: A Multi-Agent Collaborative Framework for Text-to-SQL](https://mlsanity.com/paper/2312.11242/) (2023)
- [Prompt Infection: LLM-to-LLM Prompt Injection within Multi-Agent Systems](https://mlsanity.com/paper/2410.07283/) (2024)
- [Simulating Classroom Education with LLM-Empowered Agents](https://mlsanity.com/paper/2406.19226/) (2024)
- [Advances and Challenges in Foundation Agents: From Brain-Inspired Intelligence to Evolutionary, Collaborative, and Safe Systems](https://mlsanity.com/paper/2504.01990/) (2025)
- [Towards a Science of Scaling Agent Systems](https://mlsanity.com/paper/2512.08296/) (2025)
- [A Survey of Context Engineering for Large Language Models](https://mlsanity.com/paper/2507.13334/) (2025)
- [SoK: Agentic Skills -- Beyond Tool Use in LLM Agents](https://mlsanity.com/paper/2602.20867/) (2026)
- [Memento: Fine-tuning LLM Agents without Fine-tuning LLMs](https://mlsanity.com/paper/2508.16153/) (2025)
- [WebShaper: Agentically Data Synthesizing via Information-Seeking Formalization](https://mlsanity.com/paper/2507.15061/) (2025)
- [Securing AI Agents with Information-Flow Control](https://mlsanity.com/paper/2505.23643/) (2025)
- [Agentic Large Language Models, a survey](https://mlsanity.com/paper/2503.23037/) (2025)
- [Multi-Agent Collaboration via Evolving Orchestration](https://mlsanity.com/paper/2505.19591/) (2025)
- [MARG: Multi-Agent Review Generation for Scientific Papers](https://mlsanity.com/paper/2401.04259/) (2024)
- [On the Resilience of LLM-Based Multi-Agent Collaboration with Faulty Agents](https://mlsanity.com/paper/2408.00989/) (2024)
- [SciAgents: Automating scientific discovery through multi-agent intelligent graph reasoning](https://mlsanity.com/paper/2409.05556/) (2024)
- [Agent KB: Leveraging Cross-Domain Experience for Agentic Problem Solving](https://mlsanity.com/paper/2507.06229/) (2025)
- [AgentInstruct: Toward Generative Teaching with Agentic Flows](https://mlsanity.com/paper/2407.03502/) (2024)
- [On-Policy RL Meets Off-Policy Experts: Harmonizing Supervised Fine-Tuning and Reinforcement Learning via Dynamic Weighting](https://mlsanity.com/paper/2508.11408/) (2025)

## Abstract (arXiv)

AutoGen is an open-source framework that allows developers to build LLM applications via multiple agents that can converse with each other to accomplish tasks. AutoGen agents are customizable, conversable, and can operate in various modes that employ combinations of LLMs, human inputs, and tools. Using AutoGen, developers can also flexibly define agent interaction behaviors. Both natural language and computer code can be used to program flexible conversation patterns for different applications. AutoGen serves as a generic infrastructure to build diverse applications of various complexities and LLM capacities. Empirical studies demonstrate the effectiveness of the framework in many example applications, with domains ranging from mathematics, coding, question answering, operations research, online decision-making, entertainment, etc.