# Improving Mass Detection in Mammography Images: A Study of Weakly Supervised Learning and Class Activation Map Methods

arXiv: https://arxiv.org/abs/2308.03486 · HTML: https://mlsanity.com/paper/2308.03486/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 19 of its 36 references that are in the map.
- First posted on arXiv 7 Aug 2023.

## Builds on (most cited first, 19 of 19)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Grad-CAM: Visual Explanations from Deep Networks via Gradient-based Localization](https://mlsanity.com/paper/1610.02391/) (2016)
- [Learning Deep Features for Discriminative Localization](https://mlsanity.com/paper/1512.04150/) (2015)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [Grad-CAM++: Improved Visual Explanations for Deep Convolutional Networks](https://mlsanity.com/paper/1710.11063/) (2017)
- [Adversarial Complementary Learning for Weakly Supervised Object Localization](https://mlsanity.com/paper/1804.06962/) (2018)
- [Axiom-based Grad-CAM: Towards Accurate Visualization and Explanation of CNNs](https://mlsanity.com/paper/2008.02312/) (2020)
- [End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design](https://mlsanity.com/paper/1711.05775/) (2017)
- [VinDr-Mammo: A large-scale benchmark dataset for computer-aided diagnosis in full-field digital mammography](https://mlsanity.com/paper/2203.11205/) (2022)
- [Weakly Supervised Cascaded Convolutional Networks](https://mlsanity.com/paper/1611.08258/) (2016)
- [Detecting and classifying lesions in mammograms with Deep Learning](https://mlsanity.com/paper/1707.08401/) (2017)
- [An interpretable classifier for high-resolution breast cancer screening images utilizing weakly supervised localization](https://mlsanity.com/paper/2002.07613/) (2020)
- [Deep Multi-instance Networks with Sparse Label Assignment for Whole Mammogram Classification](https://mlsanity.com/paper/1612.05968/) (2016)
- [Instance-aware Self-supervised Learning for Nuclei Segmentation](https://mlsanity.com/paper/2007.11186/) (2020)
- [Rethinking Softmax with Cross-Entropy: Neural Network Classifier as Mutual Information Estimator](https://mlsanity.com/paper/1911.10688/) (2019)
- [Revisiting The Evaluation of Class Activation Mapping for Explainability: A Novel Metric and Experimental Analysis](https://mlsanity.com/paper/2104.10252/) (2021)
- [Classification and Detection in Mammograms with Weak Supervision via Dual Branch Deep Neural Net](https://mlsanity.com/paper/1904.12319/) (2019)

## Built on by (most cited first, 1 of 1)

- [Explaining Black-box Model Predictions via Two-level Nested Feature Attributions with Consistency Property](https://mlsanity.com/paper/2405.14522/) (2024)

## Abstract (arXiv)

In recent years, weakly supervised models have aided in mass detection using mammography images, decreasing the need for pixel-level annotations. However, most existing models in the literature rely on Class Activation Maps (CAM) as the activation method, overlooking the potential benefits of exploring other activation techniques. This work presents a study that explores and compares different activation maps in conjunction with state-of-the-art methods for weakly supervised training in mammography images. Specifically, we investigate CAM, GradCAM, GradCAM++, XGradCAM, and LayerCAM methods within the framework of the GMIC model for mass detection in mammography images. The evaluation is conducted on the VinDr-Mammo dataset, utilizing the metrics Accuracy, True Positive Rate (TPR), False Negative Rate (FNR), and False Positive Per Image (FPPI). Results show that using different strategies of activation maps during training and test stages leads to an improvement of the model. With this strategy, we improve the results of the GMIC method, decreasing the FPPI value and increasing TPR.
