# RegionBLIP: A Unified Multi-modal Pre-training Framework for Holistic and Regional Comprehension

arXiv: https://arxiv.org/abs/2308.02299 · HTML: https://mlsanity.com/paper/2308.02299/

## Key facts

- Cited by 27 papers in the map (data through 14 Oct 2026).
- Placed in MLLM training and visual instruction tuning, one of 16 directions in Multimodal LLMs / vision-language models.
- Builds on 36 of its 43 references that are in the map.
- First posted on arXiv 3 Aug 2023.

## Placed in

- Multimodal LLMs / vision-language models / [MLLM training and visual instruction tuning](https://mlsanity.com/mllm/mllm-training-and-visual-instruction-tuning/)

## Builds on (most cited first, 30 of 36)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [LoRA: Low-Rank Adaptation of Large Language Models](https://mlsanity.com/paper/2106.09685/) (2021)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Flamingo: a Visual Language Model for Few-Shot Learning](https://mlsanity.com/paper/2204.14198/) (2022)
- [OPT: Open Pre-trained Transformer Language Models](https://mlsanity.com/paper/2205.01068/) (2022)
- [ScanNet: Richly-annotated 3D Reconstructions of Indoor Scenes](https://mlsanity.com/paper/1702.04405/) (2017)
- [InstructBLIP: Towards General-purpose Vision-Language Models with Instruction Tuning](https://mlsanity.com/paper/2305.06500/) (2023)
- [MiniGPT-4: Enhancing Vision-Language Understanding with Advanced Large Language Models](https://mlsanity.com/paper/2304.10592/) (2023)
- [Visual Genome: Connecting Language and Vision Using Crowdsourced Dense Image Annotations](https://mlsanity.com/paper/1602.07332/) (2016)
- [Objaverse: A Universe of Annotated 3D Objects](https://mlsanity.com/paper/2212.08051/) (2022)
- [Video-LLaMA: An Instruction-tuned Audio-Visual Language Model for Video Understanding](https://mlsanity.com/paper/2306.02858/) (2023)
- [Flickr30k Entities: Collecting Region-to-Phrase Correspondences for Richer Image-to-Sentence Models](https://mlsanity.com/paper/1505.04870/) (2015)
- [Conceptual 12M: Pushing Web-Scale Image-Text Pre-Training To Recognize Long-Tail Visual Concepts](https://mlsanity.com/paper/2102.08981/) (2021)
- [Kosmos-2: Grounding Multimodal Large Language Models to the World](https://mlsanity.com/paper/2306.14824/) (2023)
- [Modeling Context in Referring Expressions](https://mlsanity.com/paper/1608.00272/) (2016)
- [Video-ChatGPT: Towards Detailed Video Understanding via Large Vision and Language Models](https://mlsanity.com/paper/2306.05424/) (2023)
- [mPLUG-Owl: Modularization Empowers Large Language Models with Multimodality](https://mlsanity.com/paper/2304.14178/) (2023)
- [GLM: General Language Model Pretraining with Autoregressive Blank Infilling](https://mlsanity.com/paper/2103.10360/) (2021)
- [Shikra: Unleashing Multimodal LLM's Referential Dialogue Magic](https://mlsanity.com/paper/2306.15195/) (2023)
- [Generation and Comprehension of Unambiguous Object Descriptions](https://mlsanity.com/paper/1511.02283/) (2015)
- [OFA: Unifying Architectures, Tasks, and Modalities Through a Simple Sequence-to-Sequence Learning Framework](https://mlsanity.com/paper/2202.03052/) (2022)
- [EVA: Exploring the Limits of Masked Visual Representation Learning at Scale](https://mlsanity.com/paper/2211.07636/) (2022)
- [Point-BERT: Pre-training 3D Point Cloud Transformers with Masked Point Modeling](https://mlsanity.com/paper/2111.14819/) (2021)
- [Otter: A Multi-Modal Model with In-Context Instruction Tuning](https://mlsanity.com/paper/2305.03726/) (2023)
- [ScanRefer: 3D Object Localization in RGB-D Scans using Natural Language](https://mlsanity.com/paper/1912.08830/) (2019)
- [Unifying Vision-and-Language Tasks via Text Generation](https://mlsanity.com/paper/2102.02779/) (2021)
- [MultiModal-GPT: A Vision and Language Model for Dialogue with Humans](https://mlsanity.com/paper/2305.04790/) (2023)
- [Scalable 3D Captioning with Pretrained Models](https://mlsanity.com/paper/2306.07279/) (2023)

## Built on by (most cited first, 27 of 27)

- [VisionZip: Longer is Better but Not Necessary in Vision Language Models](https://mlsanity.com/paper/2412.04467/) (2024)
- [LL3DA: Visual Interactive Instruction Tuning for Omni-3D Understanding, Reasoning, and Planning](https://mlsanity.com/paper/2311.18651/) (2023)
- [ViP-LLaVA: Making Large Multimodal Models Understand Arbitrary Visual Prompts](https://mlsanity.com/paper/2312.00784/) (2023)
- [TextDiffuser-2: Unleashing the Power of Language Models for Text Rendering](https://mlsanity.com/paper/2311.16465/) (2023)
- [Draw-and-Understand: Leveraging Visual Prompts to Enable MLLMs to Comprehend What You Want](https://mlsanity.com/paper/2403.20271/) (2024)
- [Myriad: Large Multimodal Model by Applying Vision Experts for Industrial Anomaly Detection](https://mlsanity.com/paper/2310.19070/) (2023)
- [ControlMLLM: Training-Free Visual Prompt Learning for Multimodal Large Language Models](https://mlsanity.com/paper/2407.21534/) (2024)
- [3D Aware Region Prompted Vision Language Model](https://mlsanity.com/paper/2509.13317/) (2025)
- [View Selection for 3D Captioning via Diffusion Ranking](https://mlsanity.com/paper/2404.07984/) (2024)
- [Segment and Caption Anything](https://mlsanity.com/paper/2312.00869/) (2023)
- [Unified Language-driven Zero-shot Domain Adaptation](https://mlsanity.com/paper/2404.07155/) (2024)
- [EarthMarker: A Visual Prompting Multi-modal Large Language Model for Remote Sensing](https://mlsanity.com/paper/2407.13596/) (2024)
- [Voila-A: Aligning Vision-Language Models with User's Gaze Attention](https://mlsanity.com/paper/2401.09454/) (2023)
- [SCOPE: Saliency-Coverage Oriented Token Pruning for Efficient Multimodel LLMs](https://mlsanity.com/paper/2510.24214/) (2025)
- [Generative Multi-modal Models are Good Class-Incremental Learners](https://mlsanity.com/paper/2403.18383/) (2024)
- [From Google Gemini to OpenAI Q* (Q-Star): A Survey of Reshaping the Generative Artificial Intelligence (AI) Research Landscape](https://mlsanity.com/paper/2312.10868/) (2023)
- [Omni-RGPT: Unifying Image and Video Region-level Understanding via Token Marks](https://mlsanity.com/paper/2501.08326/) (2025)
- [InfMLLM: A Unified Framework for Visual-Language Tasks](https://mlsanity.com/paper/2311.06791/) (2023)
- [EarthGPT-X: A Spatial MLLM for Multi-level Multi-Source Remote Sensing Imagery Understanding with Visual Prompting](https://mlsanity.com/paper/2504.12795/) (2025)
- [Toward Interactive Regional Understanding in Vision-Large Language Models](https://mlsanity.com/paper/2403.18260/) (2024)
- [G-VOILA: Gaze-Facilitated Information Querying in Daily Scenarios](https://mlsanity.com/paper/2405.07652/) (2024)
- [Arrow-Guided VLM: Enhancing Flowchart Understanding via Arrow Direction Encoding](https://mlsanity.com/paper/2505.07864/) (2025)
- [Embodied Image Captioning: Self-supervised Learning Agents for Spatially Coherent Image Descriptions](https://mlsanity.com/paper/2504.08531/) (2025)
- [SA-Person: Text-Based Person Retrieval with Scene-aware Re-ranking](https://mlsanity.com/paper/2505.24466/) (2025)
- [Multimodal Information Fusion for Chart Understanding: A Survey of MLLMs -- Evolution, Limitations, and Cognitive Enhancement](https://mlsanity.com/paper/2602.10138/) (2026)
- [Test-Time Computing for Referring Multimodal Large Language Models](https://mlsanity.com/paper/2602.19505/) (2026)
- [VP-MEL: Visual Prompts Guided Multimodal Entity Linking](https://mlsanity.com/paper/2412.06720/) (2024)

## Abstract (arXiv)

In this work, we investigate extending the comprehension of Multi-modal Large Language Models (MLLMs) to regional objects. To this end, we propose to extract features corresponding to regional objects as soft prompts for LLM, which provides a straightforward and scalable approach and eliminates the need for LLM fine-tuning. To effectively extract regional features from regular image features and irregular point cloud features, we present a novel and unified position-assisted feature extraction module. Furthermore, training an MLLM from scratch is highly time-consuming. Thus, we propose incrementally extending existing pre-trained MLLMs to comprehend more modalities and the regional objects of those modalities. Specifically, we freeze the Q-Former from BLIP-2, an impressive MLLM, and optimize the modality-specific Lora parameters in Q-Former and LLM for each newly introduced modality. The freezing of the Q-Former eliminates the need for extensive pre-training on massive image-text data. The freezed Q-Former pre-trained from massive image-text data is also beneficial for the pre-training on image-region-text data. We name our framework RegionBLIP. We pre-train RegionBLIP on image-region-text, point-cloud-text, and point-cloud-region-text data. Experimental results verify that Ours can preserve the image comprehension capability of BILP-2 and further gain a comprehension of the newly introduced point cloud modality and regional objects. The Data, Code, and Pre-trained models will be available at https://github.com/mightyzau/RegionBLIP.