# Parse and Recall: Towards Accurate Lung Nodule Malignancy Prediction like Radiologists

arXiv: https://arxiv.org/abs/2307.10824 · HTML: https://mlsanity.com/paper/2307.10824/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 28 references that are in the map.
- First posted on arXiv 20 Jul 2023.

## Builds on (most cited first, 8 of 8)

- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [DeepLab: Semantic Image Segmentation with Deep Convolutional Nets, Atrous Convolution, and Fully Connected CRFs](https://mlsanity.com/paper/1606.00915/) (2016)
- [NLNL: Negative Learning for Noisy Labels](https://mlsanity.com/paper/1908.07387/) (2019)
- [UniMiSS: Universal Medical Self-Supervised Learning via Breaking Dimensionality Barrier](https://mlsanity.com/paper/2112.09356/) (2021)
- [Evaluate the Malignancy of Pulmonary Nodules Using the 3D Deep Leaky Noisy-or Network](https://mlsanity.com/paper/1711.08324/) (2017)
- [Learning from Ambiguous Labels for Lung Nodule Malignancy Prediction](https://mlsanity.com/paper/2104.11436/) (2021)
- [CIRDataset: A large-scale Dataset for Clinically-Interpretable lung nodule Radiomics and malignancy prediction](https://mlsanity.com/paper/2206.14903/) (2022)
- [A Cascaded Approach for ultraly High Performance Lesion Detection and False Positive Removal in Liver CT Scans](https://mlsanity.com/paper/2306.16036/) (2023)

## Built on by (most cited first, 1 of 1)

- [Super-Generalist: Towards Comprehensive and Accurate Medical Image Understanding via Generalist-Specialist Synergy](https://mlsanity.com/paper/2607.09135/) (2026)

## Abstract (arXiv)

Lung cancer is a leading cause of death worldwide and early screening is critical for improving survival outcomes. In clinical practice, the contextual structure of nodules and the accumulated experience of radiologists are the two core elements related to the accuracy of identification of benign and malignant nodules. Contextual information provides comprehensive information about nodules such as location, shape, and peripheral vessels, and experienced radiologists can search for clues from previous cases as a reference to enrich the basis of decision-making. In this paper, we propose a radiologist-inspired method to simulate the diagnostic process of radiologists, which is composed of context parsing and prototype recalling modules. The context parsing module first segments the context structure of nodules and then aggregates contextual information for a more comprehensive understanding of the nodule. The prototype recalling module utilizes prototype-based learning to condense previously learned cases as prototypes for comparative analysis, which is updated online in a momentum way during training. Building on the two modules, our method leverages both the intrinsic characteristics of the nodules and the external knowledge accumulated from other nodules to achieve a sound diagnosis. To meet the needs of both low-dose and noncontrast screening, we collect a large-scale dataset of 12,852 and 4,029 nodules from low-dose and noncontrast CTs respectively, each with pathology- or follow-up-confirmed labels. Experiments on several datasets demonstrate that our method achieves advanced screening performance on both low-dose and noncontrast scenarios.
