# Deep Neural Networks for Semiparametric Frailty Models via H-likelihood

arXiv: https://arxiv.org/abs/2307.06581 · HTML: https://mlsanity.com/paper/2307.06581/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 4 of its 29 references that are in the map.
- First posted on arXiv 13 Jul 2023.

## Builds on (most cited first, 4 of 4)

- [Time-to-Event Prediction with Neural Networks and Cox Regression](https://mlsanity.com/paper/1907.00825/) (2019)
- [Deep Neural Networks for Estimation and Inference](https://mlsanity.com/paper/1809.09953/) (2018)
- [A Selective Overview of Deep Learning](https://mlsanity.com/paper/1904.05526/) (2019)
- [Deep Learning: A Bayesian Perspective](https://mlsanity.com/paper/1706.00473/) (2017)

## Abstract (arXiv)

For prediction of clustered time-to-event data, we propose a new deep neural network based gamma frailty model (DNN-FM). An advantage of the proposed model is that the joint maximization of the new h-likelihood provides maximum likelihood estimators for fixed parameters and best unbiased predictors for random frailties. Thus, the proposed DNN-FM is trained by using a negative profiled h-likelihood as a loss function, constructed by profiling out the non-parametric baseline hazard. Experimental studies show that the proposed method enhances the prediction performance of the existing methods. A real data analysis shows that the inclusion of subject-specific frailties helps to improve prediction of the DNN based Cox model (DNN-Cox).
