# Improving Nonalcoholic Fatty Liver Disease Classification Performance With Latent Diffusion Models

arXiv: https://arxiv.org/abs/2307.06507 · HTML: https://mlsanity.com/paper/2307.06507/

## Key facts

- Cited by 4 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 10 of its 33 references that are in the map.
- First posted on arXiv 13 Jul 2023.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 10 of 10)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [EfficientNet: Rethinking Model Scaling for Convolutional Neural Networks](https://mlsanity.com/paper/1905.11946/) (2019)
- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [Improved Techniques for Training GANs](https://mlsanity.com/paper/1606.03498/) (2016)
- [EfficientNetV2: Smaller Models and Faster Training](https://mlsanity.com/paper/2104.00298/) (2021)
- [Extracting Training Data from Diffusion Models](https://mlsanity.com/paper/2301.13188/) (2023)
- [GANs Trained by a Two Time-Scale Update Rule Converge to a Local Nash Equilibrium](https://mlsanity.com/paper/1706.08500/) (2017)
- [Realistic Ultrasound Image Synthesis for Improved Classification of Liver Disease](https://mlsanity.com/paper/2107.12775/) (2021)

## Built on by (most cited first, 4 of 4)

- [A Generalist Model for Diverse Text-Guided Medical Image Synthesis](https://mlsanity.com/paper/2405.09806/) (2024)
- [Enhancing Fetal Plane Classification Accuracy with Data Augmentation Using Diffusion Models](https://mlsanity.com/paper/2501.15248/) (2025)
- [RadGazeGen: Radiomics and Gaze-guided Medical Image Generation using Diffusion Models](https://mlsanity.com/paper/2410.00307/) (2024)
- [D-Cube: Exploiting Hyper-Features of Diffusion Model for Robust Medical Classification](https://mlsanity.com/paper/2411.11087/) (2024)

## Abstract (arXiv)

Integrating deep learning with clinical expertise holds great potential for addressing healthcare challenges and empowering medical professionals with improved diagnostic tools. However, the need for annotated medical images is often an obstacle to leveraging the full power of machine learning models. Our research demonstrates that by combining synthetic images, generated using diffusion models, with real images, we can enhance nonalcoholic fatty liver disease (NAFLD) classification performance even in low-data regime settings. We evaluate the quality of the synthetic images by comparing two metrics: Inception Score (IS) and Fr'echet Inception Distance (FID), computed on diffusion- and generative adversarial network (GAN)-generated images. Our results show superior performance for the diffusion-generated images, with a maximum IS score of 1.90 compared to 1.67 for GANs, and a minimum FID score of 69.45 compared to 100.05 for GANs. Utilizing a partially frozen CNN backbone (EfficientNet v1), our synthetic augmentation method achieves a maximum image-level ROC AUC of 0.904 on a NAFLD prediction task.