# Revisiting Computer-Aided Tuberculosis Diagnosis

arXiv: https://arxiv.org/abs/2307.02848 · HTML: https://mlsanity.com/paper/2307.02848/

## Key facts

- Cited by 6 papers in the map (data through 14 Oct 2026).
- Builds on 44 of its 92 references that are in the map.
- First posted on arXiv 6 Jul 2023.

## Builds on (most cited first, 30 of 44)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Very Deep Convolutional Networks for Large-Scale Image Recognition](https://mlsanity.com/paper/1409.1556/) (2014)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Segment Anything](https://mlsanity.com/paper/2304.02643/) (2023)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [Training data-efficient image transformers & distillation through attention](https://mlsanity.com/paper/2012.12877/) (2020)
- [Delving Deep into Rectifiers: Surpassing Human-Level Performance on ImageNet Classification](https://mlsanity.com/paper/1502.01852/) (2015)
- [Deformable DETR: Deformable Transformers for End-to-End Object Detection](https://mlsanity.com/paper/2010.04159/) (2020)
- [SSD: Single Shot MultiBox Detector](https://mlsanity.com/paper/1512.02325/) (2015)
- [FCOS: Fully Convolutional One-Stage Object Detection](https://mlsanity.com/paper/1904.01355/) (2019)
- [Spatial Transformer Networks](https://mlsanity.com/paper/1506.02025/) (2015)
- [MMDetection: Open MMLab Detection Toolbox and Benchmark](https://mlsanity.com/paper/1906.07155/) (2019)
- [TransMIL: Transformer based Correlated Multiple Instance Learning for Whole Slide Image Classification](https://mlsanity.com/paper/2106.00908/) (2021)
- [TransBTS: Multimodal Brain Tumor Segmentation Using Transformer](https://mlsanity.com/paper/2103.04430/) (2021)
- [TransFuse: Fusing Transformers and CNNs for Medical Image Segmentation](https://mlsanity.com/paper/2102.08005/) (2021)
- [Transformers in Medical Imaging: A Survey](https://mlsanity.com/paper/2201.09873/) (2022)
- [CoTr: Efficiently Bridging CNN and Transformer for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.03024/) (2021)
- [Deep Learning Face Representation by Joint Identification-Verification](https://mlsanity.com/paper/1406.4773/) (2014)
- [Richer Convolutional Features for Edge Detection](https://mlsanity.com/paper/1612.02103/) (2016)
- [UTNet: A Hybrid Transformer Architecture for Medical Image Segmentation](https://mlsanity.com/paper/2107.00781/) (2021)
- [P2T: Pyramid Pooling Transformer for Scene Understanding](https://mlsanity.com/paper/2106.12011/) (2021)
- [A graph-transformer for whole slide image classification](https://mlsanity.com/paper/2205.09671/) (2022)
- [Convolution-Free Medical Image Segmentation using Transformers](https://mlsanity.com/paper/2102.13645/) (2021)
- [Multi-Compound Transformer for Accurate Biomedical Image Segmentation](https://mlsanity.com/paper/2106.14385/) (2021)

## Built on by (most cited first, 6 of 6)

- [BenchX: A Unified Benchmark Framework for Medical Vision-Language Pretraining on Chest X-Rays](https://mlsanity.com/paper/2410.21969/) (2024)
- [Prompt as Knowledge Bank: Boost Vision-language model via Structural Representation for zero-shot medical detection](https://mlsanity.com/paper/2502.16223/) (2025)
- [GAPNet: A Lightweight Framework for Image and Video Salient Object Detection via Granularity-Aware Paradigm](https://mlsanity.com/paper/2508.07585/) (2025)
- [Refining Tuberculosis Detection in CXR Imaging: Addressing Bias in Deep Neural Networks via Interpretability](https://mlsanity.com/paper/2407.14064/) (2024)
- [Weakly Supervised Tuberculosis Localization in Chest X-rays through Knowledge Distillation](https://mlsanity.com/paper/2512.11057/) (2025)
- [GRAPE: Graph-Augmented Prototype Explanations for Interactive Medical Image Diagnosis](https://mlsanity.com/paper/2606.30901/) (2026)

## Abstract (arXiv)

Tuberculosis (TB) is a major global health threat, causing millions of deaths annually. Although early diagnosis and treatment can greatly improve the chances of survival, it remains a major challenge, especially in developing countries. Recently, computer-aided tuberculosis diagnosis (CTD) using deep learning has shown promise, but progress is hindered by limited training data. To address this, we establish a large-scale dataset, namely the Tuberculosis X-ray (TBX11K) dataset, which contains 11,200 chest X-ray (CXR) images with corresponding bounding box annotations for TB areas. This dataset enables the training of sophisticated detectors for high-quality CTD. Furthermore, we propose a strong baseline, SymFormer, for simultaneous CXR image classification and TB infection area detection. SymFormer incorporates Symmetric Search Attention (SymAttention) to tackle the bilateral symmetry property of CXR images for learning discriminative features. Since CXR images may not strictly adhere to the bilateral symmetry property, we also propose Symmetric Positional Encoding (SPE) to facilitate SymAttention through feature recalibration. To promote future research on CTD, we build a benchmark by introducing evaluation metrics, evaluating baseline models reformed from existing detectors, and running an online challenge. Experiments show that SymFormer achieves state-of-the-art performance on the TBX11K dataset. The data, code, and models will be released at https://github.com/yun-liu/Tuberculosis.
