# Creating Realistic Anterior Segment Optical Coherence Tomography Images using Generative Adversarial Networks

arXiv: https://arxiv.org/abs/2306.14058 · HTML: https://mlsanity.com/paper/2306.14058/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 13 of its 35 references that are in the map.
- First posted on arXiv 24 Jun 2023.

## Builds on (most cited first, 13 of 13)

- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [ESRGAN: Enhanced Super-Resolution Generative Adversarial Networks](https://mlsanity.com/paper/1809.00219/) (2018)
- [Closed-Form Factorization of Latent Semantics in GANs](https://mlsanity.com/paper/2007.06600/) (2020)
- [Are GANs Created Equal? A Large-Scale Study](https://mlsanity.com/paper/1711.10337/) (2017)
- [GAN Augmentation: Augmenting Training Data using Generative Adversarial Networks](https://mlsanity.com/paper/1810.10863/) (2018)
- [Metrics for Deep Generative Models](https://mlsanity.com/paper/1711.01204/) (2017)
- [A Two Stage GAN for High Resolution Retinal Image Generation and Segmentation](https://mlsanity.com/paper/1907.12296/) (2019)
- [Efficient High-Resolution Deep Learning: A Survey](https://mlsanity.com/paper/2207.13050/) (2022)
- [Assessment of Generative Adversarial Networks Model for Synthetic Optical Coherence Tomography Images of Retinal Disorders](https://mlsanity.com/paper/1910.09748/) (2019)
- [Towards True Detail Restoration for Super-Resolution: A Benchmark and a Quality Metric](https://mlsanity.com/paper/2203.08923/) (2022)
- [DeshadowGAN: A Deep Learning Approach to Remove Shadows from Optical Coherence Tomography Images](https://mlsanity.com/paper/1910.02844/) (2019)
- [Generative Adversarial Networks Synthesize Realistic OCT Images of the Retina](https://mlsanity.com/paper/1902.06676/) (2019)

## Abstract (arXiv)

This paper presents the development and validation of a Generative Adversarial Network (GAN) purposed to create high-resolution, realistic Anterior Segment Optical Coherence Tomography (AS-OCT) images. We trained the Style and WAvelet based GAN (SWAGAN) on 142,628 AS-OCT B-scans. Three experienced refractive surgeons performed a blinded assessment to evaluate the realism of the generated images; their results were not significantly better than chance in distinguishing between real and synthetic images, thus demonstrating a high degree of image realism. To gauge their suitability for machine learning tasks, a convolutional neural network (CNN) classifier was trained with a dataset containing both real and GAN-generated images. The CNN demonstrated an accuracy rate of 78% trained on real images alone, but this accuracy rose to 100% when training included the generated images. This underscores the utility of synthetic images for machine learning applications. We further improved the resolution of the generated images by up-sampling them twice (2x) using an Enhanced Super Resolution GAN (ESRGAN), which outperformed traditional up-sampling techniques. In conclusion, GANs can effectively generate high-definition, realistic AS-OCT images, proving highly beneficial for machine learning and image analysis tasks.
