# Can a single image processing algorithm work equally well across all phases of DCE-MRI?

arXiv: https://arxiv.org/abs/2306.12988 · HTML: https://mlsanity.com/paper/2306.12988/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 7 of its 13 references that are in the map.
- First posted on arXiv 22 Jun 2023.

## Builds on (most cited first, 7 of 7)

- [Deep Residual Learning for Image Recognition](https://mlsanity.com/paper/1512.03385/) (2015)
- [Faster R-CNN: Towards Real-Time Object Detection with Region Proposal Networks](https://mlsanity.com/paper/1506.01497/) (2015)
- [Mask R-CNN](https://mlsanity.com/paper/1703.06870/) (2017)
- [Feature Pyramid Networks for Object Detection](https://mlsanity.com/paper/1612.03144/) (2016)
- [VoxelMorph: A Learning Framework for Deformable Medical Image Registration](https://mlsanity.com/paper/1809.05231/) (2018)
- [Unsupervised 3D End-to-End Medical Image Registration with Volume Tweening Network](https://mlsanity.com/paper/1902.05020/) (2019)
- [Automatic Renal Segmentation in DCE-MRI using Convolutional Neural Networks](https://mlsanity.com/paper/1712.07022/) (2017)

## Built on by (most cited first, 1 of 1)

- [Improving style transfer in dynamic contrast enhanced MRI using a spatio-temporal approach](https://mlsanity.com/paper/2310.01908/) (2023)

## Abstract (arXiv)

Image segmentation and registration are said to be challenging when applied to dynamic contrast enhanced MRI sequences (DCE-MRI). The contrast agent causes rapid changes in intensity in the region of interest and elsewhere, which can lead to false positive predictions for segmentation tasks and confound the image registration similarity metric. While it is widely assumed that contrast changes increase the difficulty of these tasks, to our knowledge no work has quantified these effects. In this paper we examine the effect of training with different ratios of contrast enhanced (CE) data on two popular tasks: segmentation with nnU-Net and Mask R-CNN and registration using VoxelMorph and VTN. We experimented further by strategically using the available datasets through pretraining and fine tuning with different splits of data. We found that to create a generalisable model, pretraining with CE data and fine tuning with non-CE data gave the best result. This interesting find could be expanded to other deep learning based image processing tasks with DCE-MRI and provide significant improvements to the models performance.