# BMAD: Benchmarks for Medical Anomaly Detection

arXiv: https://arxiv.org/abs/2306.11876 · HTML: https://mlsanity.com/paper/2306.11876/

## Key facts

- Cited by 82 papers in the map (data through 14 Oct 2026).
- Builds on 49 of its 81 references that are in the map.
- First posted on arXiv 20 Jun 2023.

## Builds on (most cited first, 30 of 49)

- [Variational Inference with Normalizing Flows](https://mlsanity.com/paper/1505.05770/) (2015)
- [ChestX-ray8: Hospital-scale Chest X-ray Database and Benchmarks on Weakly-Supervised Classification and Localization of Common Thorax Diseases](https://mlsanity.com/paper/1705.02315/) (2017)
- [Towards Total Recall in Industrial Anomaly Detection](https://mlsanity.com/paper/2106.08265/) (2021)
- [PaDiM: a Patch Distribution Modeling Framework for Anomaly Detection and Localization](https://mlsanity.com/paper/2011.08785/) (2020)
- [Unsupervised Anomaly Detection with Generative Adversarial Networks to Guide Marker Discovery](https://mlsanity.com/paper/1703.05921/) (2017)
- [Memorizing Normality to Detect Anomaly: Memory-augmented Deep Autoencoder for Unsupervised Anomaly Detection](https://mlsanity.com/paper/1904.02639/) (2019)
- [CutPaste: Self-Supervised Learning for Anomaly Detection and Localization](https://mlsanity.com/paper/2104.04015/) (2021)
- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [DRAEM -- A discriminatively trained reconstruction embedding for surface anomaly detection](https://mlsanity.com/paper/2108.07610/) (2021)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [Anomaly Detection via Reverse Distillation from One-Class Embedding](https://mlsanity.com/paper/2201.10703/) (2022)
- [GANomaly: Semi-Supervised Anomaly Detection via Adversarial Training](https://mlsanity.com/paper/1805.06725/) (2018)
- [Uninformed Students: Student-Teacher Anomaly Detection with Discriminative Latent Embeddings](https://mlsanity.com/paper/1911.02357/) (2019)
- [CFLOW-AD: Real-Time Unsupervised Anomaly Detection with Localization via Conditional Normalizing Flows](https://mlsanity.com/paper/2107.12571/) (2021)
- [Multiresolution Knowledge Distillation for Anomaly Detection](https://mlsanity.com/paper/2011.11108/) (2020)
- [Learning Memory-guided Normality for Anomaly Detection](https://mlsanity.com/paper/2003.13228/) (2020)
- [OpenOOD: Benchmarking Generalized Out-of-Distribution Detection](https://mlsanity.com/paper/2210.07242/) (2022)
- [Improving Unsupervised Defect Segmentation by Applying Structural Similarity to Autoencoders](https://mlsanity.com/paper/1807.02011/) (2018)
- [SimpleNet: A Simple Network for Image Anomaly Detection and Localization](https://mlsanity.com/paper/2303.15140/) (2023)
- [Diffusion Models for Medical Anomaly Detection](https://mlsanity.com/paper/2203.04306/) (2022)
- [ADBench: Anomaly Detection Benchmark](https://mlsanity.com/paper/2206.09426/) (2022)
- [FastFlow: Unsupervised Anomaly Detection and Localization via 2D Normalizing Flows](https://mlsanity.com/paper/2111.07677/) (2021)
- [Patch SVDD: Patch-level SVDD for Anomaly Detection and Segmentation](https://mlsanity.com/paper/2006.16067/) (2020)
- [Same Same But DifferNet: Semi-Supervised Defect Detection with Normalizing Flows](https://mlsanity.com/paper/2008.12577/) (2020)
- [Adversarially Learned One-Class Classifier for Novelty Detection](https://mlsanity.com/paper/1802.09088/) (2018)
- [OCGAN: One-class Novelty Detection Using GANs with Constrained Latent Representations](https://mlsanity.com/paper/1903.08550/) (2019)
- [CFA: Coupled-hypersphere-based Feature Adaptation for Target-Oriented Anomaly Localization](https://mlsanity.com/paper/2206.04325/) (2022)
- [Fully Convolutional Cross-Scale-Flows for Image-based Defect Detection](https://mlsanity.com/paper/2110.02855/) (2021)
- [Asymmetric Student-Teacher Networks for Industrial Anomaly Detection](https://mlsanity.com/paper/2210.07829/) (2022)
- [Unsupervised Detection of Lesions in Brain MRI using constrained adversarial auto-encoders](https://mlsanity.com/paper/1806.04972/) (2018)

## Built on by (most cited first, 30 of 82)

- [MambaAD: Exploring State Space Models for Multi-class Unsupervised Anomaly Detection](https://mlsanity.com/paper/2404.06564/) (2024)
- [Adapting Visual-Language Models for Generalizable Anomaly Detection in Medical Images](https://mlsanity.com/paper/2403.12570/) (2024)
- [Towards Zero-Shot Anomaly Detection and Reasoning with Multimodal Large Language Models](https://mlsanity.com/paper/2502.07601/) (2025)
- [Exploring Plain ViT Reconstruction for Multi-class Unsupervised Anomaly Detection](https://mlsanity.com/paper/2312.07495/) (2023)
- [DiAD: A Diffusion-based Framework for Multi-class Anomaly Detection](https://mlsanity.com/paper/2312.06607/) (2023)
- [UniVAD: A Training-free Unified Model for Few-shot Visual Anomaly Detection](https://mlsanity.com/paper/2412.03342/) (2024)
- [MedIAnomaly: A comparative study of anomaly detection in medical images](https://mlsanity.com/paper/2404.04518/) (2024)
- [3D-RAD: A Comprehensive 3D Radiology Med-VQA Dataset with Multi-Temporal Analysis and Diverse Diagnostic Tasks](https://mlsanity.com/paper/2506.11147/) (2025)
- [IC3M: In-Car Multimodal Multi-object Monitoring for Abnormal Status of Both Driver and Passengers](https://mlsanity.com/paper/2410.02592/) (2024)
- [PaSTe: Improving the Efficiency of Visual Anomaly Detection at the Edge](https://mlsanity.com/paper/2410.11591/) (2024)
- [Unveiling the Anomalies in an Ever-Changing World: A Benchmark for Pixel-Level Anomaly Detection in Continual Learning](https://mlsanity.com/paper/2403.15463/) (2024)
- [Dynamic Uncertainty-aware Multimodal Fusion for Outdoor Health Monitoring](https://mlsanity.com/paper/2508.09085/) (2025)
- [FiLo++: Zero-/Few-Shot Anomaly Detection by Fused Fine-Grained Descriptions and Deformable Localization](https://mlsanity.com/paper/2501.10067/) (2025)
- [Extremely Simple Multimodal Outlier Synthesis for Out-of-Distribution Detection and Segmentation](https://mlsanity.com/paper/2505.16985/) (2025)
- [AnomalyMoE: Towards a Language-free Generalist Model for Unified Visual Anomaly Detection](https://mlsanity.com/paper/2508.06203/) (2025)
- [MedDiff-FM: A Diffusion-based Foundation Model for Versatile Medical Image Applications](https://mlsanity.com/paper/2410.15432/) (2024)
- [Applications of Large Models in Medicine](https://mlsanity.com/paper/2502.17132/) (2025)
- [Dinomaly2: A Unified Framework for Unsupervised Image Anomaly Detection](https://mlsanity.com/paper/2510.17611/) (2025)
- [Is Hyperbolic Space All You Need for Medical Anomaly Detection?](https://mlsanity.com/paper/2505.21228/) (2025)
- [Anomaly Detection by Clustering DINO Embeddings using a Dirichlet Process Mixture](https://mlsanity.com/paper/2509.19997/) (2025)
- [Bidirectional Multimodal Prompt Learning with Scale-Aware Training for Few-Shot Multi-Class Anomaly Detection](https://mlsanity.com/paper/2408.13516/) (2024)
- [Memory Efficient Continual Learning for Edge-Based Visual Anomaly Detection](https://mlsanity.com/paper/2503.02691/) (2025)
- [We Need to Rethink Benchmarking in Anomaly Detection](https://mlsanity.com/paper/2507.15584/) (2025)
- [No Label Left Behind: A Unified Surface Defect Detection Model for all Supervision Regimes](https://mlsanity.com/paper/2508.19060/) (2025)
- [InvAD: Inversion-based Reconstruction-Free Anomaly Detection with Diffusion Models](https://mlsanity.com/paper/2504.05662/) (2025)
- [ALFred: An Active Learning Framework for Real-world Semi-supervised Anomaly Detection with Adaptive Thresholds](https://mlsanity.com/paper/2508.09058/) (2025)
- [Towards Continual Visual Anomaly Detection in the Medical Domain](https://mlsanity.com/paper/2508.18013/) (2025)
- [Contrastive Language Prompting to Ease False Positives in Medical Anomaly Detection](https://mlsanity.com/paper/2411.07546/) (2024)
- [FlowCLAS: Enhancing Normalizing Flow Via Contrastive Learning For Anomaly Segmentation](https://mlsanity.com/paper/2411.19888/) (2024)
- [MADPOT: Medical Anomaly Detection with CLIP Adaptation and Partial Optimal Transport](https://mlsanity.com/paper/2507.06733/) (2025)

## Abstract (arXiv)

Anomaly detection (AD) is a fundamental research problem in machine learning and computer vision, with practical applications in industrial inspection, video surveillance, and medical diagnosis. In medical imaging, AD is especially vital for detecting and diagnosing anomalies that may indicate rare diseases or conditions. However, there is a lack of a universal and fair benchmark for evaluating AD methods on medical images, which hinders the development of more generalized and robust AD methods in this specific domain. To bridge this gap, we introduce a comprehensive evaluation benchmark for assessing anomaly detection methods on medical images. This benchmark encompasses six reorganized datasets from five medical domains (i.e. brain MRI, liver CT, retinal OCT, chest X-ray, and digital histopathology) and three key evaluation metrics, and includes a total of fourteen state-of-the-art AD algorithms. This standardized and well-curated medical benchmark with the well-structured codebase enables comprehensive comparisons among recently proposed anomaly detection methods. It will facilitate the community to conduct a fair comparison and advance the field of AD on medical imaging. More information on BMAD is available in our GitHub repository: https://github.com/DorisBao/BMAD