# Diff-Instruct: A Universal Approach for Transferring Knowledge From Pre-trained Diffusion Models

arXiv: https://arxiv.org/abs/2305.18455 · HTML: https://mlsanity.com/paper/2305.18455/

## Key facts

- Cited by 236 papers in the map (data through 14 Oct 2026).
- Placed in Diffusion foundations and sampling, one of 14 directions in Diffusion models.
- Builds on 68 of its 82 references that are in the map.
- First posted on arXiv 29 May 2023.

## Placed in

- Diffusion models / [Diffusion foundations and sampling](https://mlsanity.com/diffusion/diffusion-foundations-and-sampling/)

## Builds on (most cited first, 30 of 68)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [The Unreasonable Effectiveness of Deep Features as a Perceptual Metric](https://mlsanity.com/paper/1801.03924/) (2018)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Hierarchical Text-Conditional Image Generation with CLIP Latents](https://mlsanity.com/paper/2204.06125/) (2022)
- [Photorealistic Text-to-Image Diffusion Models with Deep Language Understanding](https://mlsanity.com/paper/2205.11487/) (2022)
- [A Style-Based Generator Architecture for Generative Adversarial Networks](https://mlsanity.com/paper/1812.04948/) (2018)
- [Zero-Shot Text-to-Image Generation](https://mlsanity.com/paper/2102.12092/) (2021)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Flow Straight and Fast: Learning to Generate and Transfer Data with Rectified Flow](https://mlsanity.com/paper/2209.03003/) (2022)
- [GLIDE: Towards Photorealistic Image Generation and Editing with Text-Guided Diffusion Models](https://mlsanity.com/paper/2112.10741/) (2021)
- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [Elucidating the Design Space of Diffusion-Based Generative Models](https://mlsanity.com/paper/2206.00364/) (2022)
- [DreamFusion: Text-to-3D using 2D Diffusion](https://mlsanity.com/paper/2209.14988/) (2022)
- [Improved Techniques for Training GANs](https://mlsanity.com/paper/1606.03498/) (2016)
- [Large Scale GAN Training for High Fidelity Natural Image Synthesis](https://mlsanity.com/paper/1809.11096/) (2018)
- [Video Diffusion Models](https://mlsanity.com/paper/2204.03458/) (2022)
- [DPM-Solver: A Fast ODE Solver for Diffusion Probabilistic Model Sampling in Around 10 Steps](https://mlsanity.com/paper/2206.00927/) (2022)
- [Consistency Models](https://mlsanity.com/paper/2303.01469/) (2023)
- [Imagen Video: High Definition Video Generation with Diffusion Models](https://mlsanity.com/paper/2210.02303/) (2022)
- [WaveNet: A Generative Model for Raw Audio](https://mlsanity.com/paper/1609.03499/) (2016)
- [Spectral Normalization for Generative Adversarial Networks](https://mlsanity.com/paper/1802.05957/) (2018)
- [Glow: Generative Flow with Invertible 1x1 Convolutions](https://mlsanity.com/paper/1807.03039/) (2018)
- [Model soups: averaging weights of multiple fine-tuned models improves accuracy without increasing inference time](https://mlsanity.com/paper/2203.05482/) (2022)
- [Magic3D: High-Resolution Text-to-3D Content Creation](https://mlsanity.com/paper/2211.10440/) (2022)
- [Training Generative Adversarial Networks with Limited Data](https://mlsanity.com/paper/2006.06676/) (2020)
- [Alias-Free Generative Adversarial Networks](https://mlsanity.com/paper/2106.12423/) (2021)
- [Least Squares Generative Adversarial Networks](https://mlsanity.com/paper/1611.04076/) (2016)

## Built on by (most cited first, 30 of 236)

- [One-step Diffusion with Distribution Matching Distillation](https://mlsanity.com/paper/2311.18828/) (2023)
- [Adversarial Diffusion Distillation](https://mlsanity.com/paper/2311.17042/) (2023)
- [Improved Distribution Matching Distillation for Fast Image Synthesis](https://mlsanity.com/paper/2405.14867/) (2024)
- [Self Forcing: Bridging the Train-Test Gap in Autoregressive Video Diffusion](https://mlsanity.com/paper/2506.08009/) (2025)
- [Mean Flows for One-step Generative Modeling](https://mlsanity.com/paper/2505.13447/) (2025)
- [Improved Techniques for Training Consistency Models](https://mlsanity.com/paper/2310.14189/) (2023)
- [From Slow Bidirectional to Fast Autoregressive Video Diffusion Models](https://mlsanity.com/paper/2412.07772/) (2024)
- [LucidDreamer: Towards High-Fidelity Text-to-3D Generation via Interval Score Matching](https://mlsanity.com/paper/2311.11284/) (2023)
- [Simplifying, Stabilizing and Scaling Continuous-Time Consistency Models](https://mlsanity.com/paper/2410.11081/) (2024)
- [Score identity Distillation: Exponentially Fast Distillation of Pretrained Diffusion Models for One-Step Generation](https://mlsanity.com/paper/2404.04057/) (2024)
- [Causal Forcing: Autoregressive Diffusion Distillation Done Right for High-Quality Real-Time Interactive Video Generation](https://mlsanity.com/paper/2602.02214/) (2026)
- [Diffusion Adversarial Post-Training for One-Step Video Generation](https://mlsanity.com/paper/2501.08316/) (2025)
- [Consistency Models Made Easy](https://mlsanity.com/paper/2406.14548/) (2024)
- [Generative Modeling via Drifting](https://mlsanity.com/paper/2602.04770/) (2026)
- [Inductive Moment Matching](https://mlsanity.com/paper/2503.07565/) (2025)
- [SwiftBrush: One-Step Text-to-Image Diffusion Model with Variational Score Distillation](https://mlsanity.com/paper/2312.05239/) (2023)
- [Improving the Training of Rectified Flows](https://mlsanity.com/paper/2405.20320/) (2024)
- [Consistency Flow Matching: Defining Straight Flows with Velocity Consistency](https://mlsanity.com/paper/2407.02398/) (2024)
- [Autoregressive Adversarial Post-Training for Real-Time Interactive Video Generation](https://mlsanity.com/paper/2506.09350/) (2025)
- [One-Step Diffusion Policy: Fast Visuomotor Policies via Diffusion Distillation](https://mlsanity.com/paper/2410.21257/) (2024)
- [SANA-Sprint: One-Step Diffusion with Continuous-Time Consistency Distillation](https://mlsanity.com/paper/2503.09641/) (2025)
- [Align Your Flow: Scaling Continuous-Time Flow Map Distillation](https://mlsanity.com/paper/2506.14603/) (2025)
- [Large Scale Diffusion Distillation via Score-Regularized Continuous-Time Consistency](https://mlsanity.com/paper/2510.08431/) (2025)
- [Multistep Distillation of Diffusion Models via Moment Matching](https://mlsanity.com/paper/2406.04103/) (2024)
- [Beyond Autoregression: Fast LLMs via Self-Distillation Through Time](https://mlsanity.com/paper/2410.21035/) (2024)
- [Simpler Diffusion (SiD2): 1.5 FID on ImageNet512 with pixel-space diffusion](https://mlsanity.com/paper/2410.19324/) (2024)
- [One-Step Diffusion Distillation through Score Implicit Matching](https://mlsanity.com/paper/2410.16794/) (2024)
- [Accelerating Diffusion Sampling with Optimized Time Steps](https://mlsanity.com/paper/2402.17376/) (2024)
- [Multistep Consistency Models](https://mlsanity.com/paper/2403.06807/) (2024)
- [EM Distillation for One-step Diffusion Models](https://mlsanity.com/paper/2405.16852/) (2024)

## Abstract (arXiv)

Due to the ease of training, ability to scale, and high sample quality, diffusion models (DMs) have become the preferred option for generative modeling, with numerous pre-trained models available for a wide variety of datasets. Containing intricate information about data distributions, pre-trained DMs are valuable assets for downstream applications. In this work, we consider learning from pre-trained DMs and transferring their knowledge to other generative models in a data-free fashion. Specifically, we propose a general framework called Diff-Instruct to instruct the training of arbitrary generative models as long as the generated samples are differentiable with respect to the model parameters. Our proposed Diff-Instruct is built on a rigorous mathematical foundation where the instruction process directly corresponds to minimizing a novel divergence we call Integral Kullback-Leibler (IKL) divergence. IKL is tailored for DMs by calculating the integral of the KL divergence along a diffusion process, which we show to be more robust in comparing distributions with misaligned supports. We also reveal non-trivial connections of our method to existing works such as DreamFusion, and generative adversarial training. To demonstrate the effectiveness and universality of Diff-Instruct, we consider two scenarios: distilling pre-trained diffusion models and refining existing GAN models. The experiments on distilling pre-trained diffusion models show that Diff-Instruct results in state-of-the-art single-step diffusion-based models. The experiments on refining GAN models show that the Diff-Instruct can consistently improve the pre-trained generators of GAN models across various settings.