# Attention Mechanisms in Medical Image Segmentation: A Survey

arXiv: https://arxiv.org/abs/2305.17937 · HTML: https://mlsanity.com/paper/2305.17937/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 156 of its 332 references that are in the map.
- First posted on arXiv 29 May 2023.

## Builds on (most cited first, 30 of 156)

- [Attention Is All You Need](https://mlsanity.com/paper/1706.03762/) (2017)
- [An Image is Worth 16x16 Words: Transformers for Image Recognition at Scale](https://mlsanity.com/paper/2010.11929/) (2020)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [End-to-End Object Detection with Transformers](https://mlsanity.com/paper/2005.12872/) (2020)
- [Squeeze-and-Excitation Networks](https://mlsanity.com/paper/1709.01507/) (2017)
- [Deformable DETR: Deformable Transformers for End-to-End Object Detection](https://mlsanity.com/paper/2010.04159/) (2020)
- [SegFormer: Simple and Efficient Design for Semantic Segmentation with Transformers](https://mlsanity.com/paper/2105.15203/) (2021)
- [CBAM: Convolutional Block Attention Module](https://mlsanity.com/paper/1807.06521/) (2018)
- [Non-local Neural Networks](https://mlsanity.com/paper/1711.07971/) (2017)
- [Pyramid Vision Transformer: A Versatile Backbone for Dense Prediction without Convolutions](https://mlsanity.com/paper/2102.12122/) (2021)
- [TransUNet: Transformers Make Strong Encoders for Medical Image Segmentation](https://mlsanity.com/paper/2102.04306/) (2021)
- [Attention U-Net: Learning Where to Look for the Pancreas](https://mlsanity.com/paper/1804.03999/) (2018)
- [Rethinking Semantic Segmentation from a Sequence-to-Sequence Perspective with Transformers](https://mlsanity.com/paper/2012.15840/) (2020)
- [Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentation](https://mlsanity.com/paper/2105.05537/) (2021)
- [Dual Attention Network for Scene Segmentation](https://mlsanity.com/paper/1809.02983/) (2018)
- [UNETR: Transformers for 3D Medical Image Segmentation](https://mlsanity.com/paper/2103.10504/) (2021)
- [Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Images](https://mlsanity.com/paper/2201.01266/) (2022)
- [Self-Attention Generative Adversarial Networks](https://mlsanity.com/paper/1805.08318/) (2018)
- [CCNet: Criss-Cross Attention for Semantic Segmentation](https://mlsanity.com/paper/1811.11721/) (2018)
- [The Medical Segmentation Decathlon](https://mlsanity.com/paper/2106.05735/) (2021)
- [Kvasir-SEG: A Segmented Polyp Dataset](https://mlsanity.com/paper/1911.07069/) (2019)
- [ECA-Net: Efficient Channel Attention for Deep Convolutional Neural Networks](https://mlsanity.com/paper/1910.03151/) (2019)
- [Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)](https://mlsanity.com/paper/1710.05006/) (2017)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [The Liver Tumor Segmentation Benchmark (LiTS)](https://mlsanity.com/paper/1901.04056/) (2019)
- [LeViT: a Vision Transformer in ConvNet's Clothing for Faster Inference](https://mlsanity.com/paper/2104.01136/) (2021)
- [PraNet: Parallel Reverse Attention Network for Polyp Segmentation](https://mlsanity.com/paper/2006.11392/) (2020)
- [Self-Supervised Pre-Training of Swin Transformers for 3D Medical Image Analysis](https://mlsanity.com/paper/2111.14791/) (2021)
- [GCNet: Non-local Networks Meet Squeeze-Excitation Networks and Beyond](https://mlsanity.com/paper/1904.11492/) (2019)
- [CHAOS Challenge -- Combined (CT-MR) Healthy Abdominal Organ Segmentation](https://mlsanity.com/paper/2001.06535/) (2020)

## Built on by (most cited first, 9 of 9)

- [LGPS: A Lightweight GAN-Based Approach for Polyp Segmentation in Colonoscopy Images](https://mlsanity.com/paper/2503.18294/) (2025)
- [Integrating Biological and Machine Intelligence: Attention Mechanisms in Brain-Computer Interfaces](https://mlsanity.com/paper/2502.19281/) (2025)
- [GeloVec: Higher Dimensional Geometric Smoothing for Coherent Visual Feature Extraction in Image Segmentation](https://mlsanity.com/paper/2505.01057/) (2025)
- [XBusNet: Text-Guided Breast Ultrasound Segmentation via Multimodal Vision-Language Learning](https://mlsanity.com/paper/2509.07213/) (2025)
- [Vertical Federated Image Segmentation](https://mlsanity.com/paper/2401.07931/) (2024)
- [NAADA: A Noise-Aware Attention Denoising Autoencoder for Dental Panoramic Radiographs](https://mlsanity.com/paper/2506.19387/) (2025)
- [AI-CNet3D: An Anatomically-Informed Cross-Attention Network with Multi-Task Consistency Fine-tuning for 3D Glaucoma Classification](https://mlsanity.com/paper/2510.00882/) (2025)
- [Adaptive Dual Residual U-Net with Attention Gate and Multiscale Spatial Attention Mechanisms (ADRUwAMS)](https://mlsanity.com/paper/2604.08893/) (2026)
- [MedCAGD: Context-Aware Gated Decoder for Efficient Medical Image Segmentation](https://mlsanity.com/paper/2607.00409/) (2026)

## Abstract (arXiv)

Medical image segmentation plays an important role in computer-aided diagnosis. Attention mechanisms that distinguish important parts from irrelevant parts have been widely used in medical image segmentation tasks. This paper systematically reviews the basic principles of attention mechanisms and their applications in medical image segmentation. First, we review the basic concepts of attention mechanism and formulation. Second, we surveyed over 300 articles related to medical image segmentation, and divided them into two groups based on their attention mechanisms, non-Transformer attention and Transformer attention. In each group, we deeply analyze the attention mechanisms from three aspects based on the current literature work, i.e., the principle of the mechanism (what to use), implementation methods (how to use), and application tasks (where to use). We also thoroughly analyzed the advantages and limitations of their applications to different tasks. Finally, we summarize the current state of research and shortcomings in the field, and discuss the potential challenges in the future, including task specificity, robustness, standard evaluation, etc. We hope that this review can showcase the overall research context of traditional and Transformer attention methods, provide a clear reference for subsequent research, and inspire more advanced attention research, not only in medical image segmentation, but also in other image analysis scenarios.
