# The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs)

arXiv: https://arxiv.org/abs/2305.17033 · HTML: https://mlsanity.com/paper/2305.17033/

## Key facts

- Cited by 49 papers in the map (data through 14 Oct 2026).
- Builds on 3 of its 34 references that are in the map.
- First posted on arXiv 26 May 2023.

## Builds on (most cited first, 3 of 3)

- [The RSNA-ASNR-MICCAI BraTS 2021 Benchmark on Brain Tumor Segmentation and Radiogenomic Classification](https://mlsanity.com/paper/2107.02314/) (2021)
- [Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challenge](https://mlsanity.com/paper/1811.02629/) (2018)
- [GaNDLF: A Generally Nuanced Deep Learning Framework for Scalable End-to-End Clinical Workflows in Medical Imaging](https://mlsanity.com/paper/2103.01006/) (2021)

## Built on by (most cited first, 30 of 49)

- [SegMamba: Long-range Sequential Modeling Mamba For 3D Medical Image Segmentation](https://mlsanity.com/paper/2401.13560/) (2024)
- [BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at once](https://mlsanity.com/paper/2405.12971/) (2024)
- [The 2024 Brain Tumor Segmentation (BraTS) Challenge: Glioma Segmentation on Post-treatment MRI](https://mlsanity.com/paper/2405.18368/) (2024)
- [Large-Vocabulary Segmentation for Medical Images with Text Prompts](https://mlsanity.com/paper/2312.17183/) (2023)
- [Foundation Models for Biomedical Image Segmentation: A Survey](https://mlsanity.com/paper/2401.07654/) (2024)
- [Cross-conditioned Diffusion Model for Medical Image to Image Translation](https://mlsanity.com/paper/2409.08500/) (2024)
- [AutoRG-Brain: Grounded Report Generation for Brain MRI](https://mlsanity.com/paper/2407.16684/) (2024)
- [Multi-modal Vision Pre-training for Medical Image Analysis](https://mlsanity.com/paper/2410.10604/) (2024)
- [Towards Scalable Language-Image Pre-training for 3D Medical Imaging](https://mlsanity.com/paper/2505.21862/) (2025)
- [Advanced Tumor Segmentation in Medical Imaging: An Ensemble Approach for BraTS 2023 Adult Glioma and Pediatric Tumor Tasks](https://mlsanity.com/paper/2403.09262/) (2024)
- [xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpart](https://mlsanity.com/paper/2407.01530/) (2024)
- [BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023](https://mlsanity.com/paper/2407.08855/) (2024)
- [Anomaly Detection and Generation with Diffusion Models: A Survey](https://mlsanity.com/paper/2506.09368/) (2025)
- [A large-scale heterogeneous 3D magnetic resonance brain imaging dataset for self-supervised learning](https://mlsanity.com/paper/2506.14432/) (2025)
- [Model Ensemble for Brain Tumor Segmentation in Magnetic Resonance Imaging](https://mlsanity.com/paper/2409.08232/) (2024)
- [Federated brain tumor segmentation: an extensive benchmark](https://mlsanity.com/paper/2410.17265/) (2024)
- [Autoregressive Sequence Modeling for 3D Medical Image Representation](https://mlsanity.com/paper/2409.08691/) (2024)
- [BrainDINO: A Brain MRI Foundation Model for Generalizable Clinical Representation Learning](https://mlsanity.com/paper/2604.27277/) (2026)
- [On Enhancing Brain Tumor Segmentation Across Diverse Populations with Convolutional Neural Networks](https://mlsanity.com/paper/2405.02852/) (2024)
- [Domain Game: Disentangle Anatomical Feature for Single Domain Generalized Segmentation](https://mlsanity.com/paper/2406.02125/) (2024)
- [Unsupervised Domain Adaptation for Pediatric Brain Tumor Segmentation](https://mlsanity.com/paper/2406.16848/) (2024)
- [SAM-aware Test-time Adaptation for Universal Medical Image Segmentation](https://mlsanity.com/paper/2506.05221/) (2025)
- [MARL-MambaContour: Unleashing Multi-Agent Deep Reinforcement Learning for Active Contour Optimization in Medical Image Segmentation](https://mlsanity.com/paper/2506.18679/) (2025)
- [Automated 3D Tumor Segmentation using Temporal Cubic PatchGAN (TCuP-GAN)](https://mlsanity.com/paper/2311.14148/) (2023)
- [GBT-SAM: A Parameter-Efficient Depth-Aware Model for Generalizable Brain tumour Segmentation on mp-MRI](https://mlsanity.com/paper/2503.04325/) (2025)
- [WaveFormer: A 3D Transformer with Wavelet-Driven Feature Representation for Efficient Medical Image Segmentation](https://mlsanity.com/paper/2503.23764/) (2025)
- [Multiscale Encoder and Omni-Dimensional Dynamic Convolution Enrichment in nnU-Net for Brain Tumor Segmentation](https://mlsanity.com/paper/2409.13229/) (2024)
- [A New Logic For Pediatric Brain Tumor Segmentation](https://mlsanity.com/paper/2411.01390/) (2024)
- [Safeguarding AI in Medical Imaging: Post-Hoc Out-of-Distribution Detection with Normalizing Flows](https://mlsanity.com/paper/2502.11638/) (2025)
- [Automated segmentation of pediatric neuroblastoma on multi-modal MRI: Results of the SPPIN challenge at MICCAI 2023](https://mlsanity.com/paper/2505.00369/) (2025)

## Abstract (arXiv)

Pediatric tumors of the central nervous system are the most common cause of cancer-related death in children. The five-year survival rate for high-grade gliomas in children is less than 20%. Due to their rarity, the diagnosis of these entities is often delayed, their treatment is mainly based on historic treatment concepts, and clinical trials require multi-institutional collaborations. The MICCAI Brain Tumor Segmentation (BraTS) Challenge is a landmark community benchmark event with a successful history of 12 years of resource creation for the segmentation and analysis of adult glioma. Here we present the CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge, which represents the first BraTS challenge focused on pediatric brain tumors with data acquired across multiple international consortia dedicated to pediatric neuro-oncology and clinical trials. The BraTS-PEDs 2023 challenge focuses on benchmarking the development of volumentric segmentation algorithms for pediatric brain glioma through standardized quantitative performance evaluation metrics utilized across the BraTS 2023 cluster of challenges. Models gaining knowledge from the BraTS-PEDs multi-parametric structural MRI (mpMRI) training data will be evaluated on separate validation and unseen test mpMRI dataof high-grade pediatric glioma. The CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs 2023 challenge brings together clinicians and AI/imaging scientists to lead to faster development of automated segmentation techniques that could benefit clinical trials, and ultimately the care of children with brain tumors.
