# Brain Captioning: Decoding human brain activity into images and text

arXiv: https://arxiv.org/abs/2305.11560 · HTML: https://mlsanity.com/paper/2305.11560/

## Key facts

- Cited by 34 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 19 of its 33 references that are in the map.
- First posted on arXiv 19 May 2023.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 19 of 19)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Adding Conditional Control to Text-to-Image Diffusion Models](https://mlsanity.com/paper/2302.05543/) (2023)
- [Vision Transformers for Dense Prediction](https://mlsanity.com/paper/2103.13413/) (2021)
- [GIT: A Generative Image-to-text Transformer for Vision and Language](https://mlsanity.com/paper/2205.14100/) (2022)
- [Very Deep VAEs Generalize Autoregressive Models and Can Outperform Them on Images](https://mlsanity.com/paper/2011.10650/) (2020)
- [Large Scale Adversarial Representation Learning](https://mlsanity.com/paper/1907.02544/) (2019)
- [Seeing Beyond the Brain: Conditional Diffusion Model with Sparse Masked Modeling for Vision Decoding](https://mlsanity.com/paper/2211.06956/) (2022)
- [Instance-Conditioned GAN](https://mlsanity.com/paper/2109.05070/) (2021)
- [Generic decoding of seen and imagined objects using hierarchical visual features](https://mlsanity.com/paper/1510.06479/) (2015)
- [Learnable latent embeddings for joint behavioral and neural analysis](https://mlsanity.com/paper/2204.00673/) (2022)
- [Mind Reader: Reconstructing complex images from brain activities](https://mlsanity.com/paper/2210.01769/) (2022)
- [Convolutional Neural Networks as a Model of the Visual System: Past, Present, and Future](https://mlsanity.com/paper/2001.07092/) (2020)
- [Reconstruction of Perceived Images from fMRI Patterns and Semantic Brain Exploration using Instance-Conditioned GANs](https://mlsanity.com/paper/2202.12692/) (2022)
- [Reconstructing Natural Scenes from fMRI Patterns using BigBiGAN](https://mlsanity.com/paper/2001.11761/) (2020)
- [Reconstructing Faces from fMRI Patterns using Deep Generative Neural Networks](https://mlsanity.com/paper/1810.03856/) (2018)
- [Semantic Brain Decoding: from fMRI to conceptually similar image reconstruction of visual stimuli](https://mlsanity.com/paper/2212.06726/) (2022)
- [Reconstructing Perceived Images from Brain Activity by Visually-guided Cognitive Representation and Adversarial Learning](https://mlsanity.com/paper/1906.12181/) (2019)
- [Multimodal neural networks better explain multivoxel patterns in the hippocampus](https://mlsanity.com/paper/2201.11517/) (2021)

## Built on by (most cited first, 30 of 34)

- [MindEye2: Shared-Subject Models Enable fMRI-To-Image With 1 Hour of Data](https://mlsanity.com/paper/2403.11207/) (2024)
- [DREAM: Visual Decoding from Reversing Human Visual System](https://mlsanity.com/paper/2310.02265/) (2023)
- [NeuroPictor: Refining fMRI-to-Image Reconstruction via Multi-individual Pretraining and Multi-level Modulation](https://mlsanity.com/paper/2403.18211/) (2024)
- [UMBRAE: Unified Multimodal Brain Decoding](https://mlsanity.com/paper/2404.07202/) (2024)
- [Improving visual image reconstruction from human brain activity using latent diffusion models via multiple decoded inputs](https://mlsanity.com/paper/2306.11536/) (2023)
- [Through their eyes: multi-subject Brain Decoding with simple alignment techniques](https://mlsanity.com/paper/2309.00627/) (2023)
- [BrainSCUBA: Fine-Grained Natural Language Captions of Visual Cortex Selectivity](https://mlsanity.com/paper/2310.04420/) (2023)
- [Brain-Conditional Multimodal Synthesis: A Survey and Taxonomy](https://mlsanity.com/paper/2401.00430/) (2023)
- [MindLLM: A Subject-Agnostic and Versatile Model for fMRI-to-Text Decoding](https://mlsanity.com/paper/2502.15786/) (2025)
- [Brain Mapping with Dense Features: Grounding Cortical Semantic Selectivity in Natural Images With Vision Transformers](https://mlsanity.com/paper/2410.05266/) (2024)
- [Decoding visual brain representations from electroencephalography through Knowledge Distillation and latent diffusion models](https://mlsanity.com/paper/2309.07149/) (2023)
- [Aligning brain functions boosts the decoding of visual semantics in novel subjects](https://mlsanity.com/paper/2312.06467/) (2023)
- [A Survey on fMRI-based Brain Decoding for Reconstructing Multimodal Stimuli](https://mlsanity.com/paper/2503.15978/) (2025)
- [ZEBRA: Towards Zero-Shot Cross-Subject Generalization for Universal Brain Visual Decoding](https://mlsanity.com/paper/2510.27128/) (2025)
- [MindGPT: Interpreting What You See with Non-invasive Brain Recordings](https://mlsanity.com/paper/2309.15729/) (2023)
- [COBRA: A Continual Learning Approach to Vision-Brain Understanding](https://mlsanity.com/paper/2411.17475/) (2024)
- [Exploring The Visual Feature Space for Multimodal Neural Decoding](https://mlsanity.com/paper/2505.15755/) (2025)
- [Meta-Learning an In-Context Transformer Model of Human Higher Visual Cortex](https://mlsanity.com/paper/2505.15813/) (2025)
- [LLM4Brain: Training a Large Language Model for Brain Video Understanding](https://mlsanity.com/paper/2409.17987/) (2024)
- [Optimal Transport for Brain-Image Alignment: Unveiling Redundancy and Synergy in Neural Information Processing](https://mlsanity.com/paper/2503.10663/) (2025)
- [Decoding the Multimodal Mind: Generalizable Brain-to-Text Translation via Multimodal Alignment and Adaptive Routing](https://mlsanity.com/paper/2505.10356/) (2025)
- [BrainDecoder: Style-Based Visual Decoding of EEG Signals](https://mlsanity.com/paper/2409.05279/) (2024)
- [Meta-learning In-Context Enables Training-Free Cross Subject Brain Decoding](https://mlsanity.com/paper/2604.08537/) (2026)
- [FPED: A Functional-Network Prior-Guided Mixture-of-Experts Framework for Interpretable Brain Decoding](https://mlsanity.com/paper/2605.19279/) (2026)
- [Large-scale Foundation Models and Generative AI for BigData Neuroscience](https://mlsanity.com/paper/2310.18377/) (2023)
- [Decoding fMRI Data into Captions using Prefix Language Modeling](https://mlsanity.com/paper/2501.02570/) (2025)
- [The Pictorial Cortex: Zero-Shot Cross-Subject fMRI-to-Image Reconstruction via Compositional Latent Modeling](https://mlsanity.com/paper/2601.15071/) (2026)
- [NeuroFlow: Toward Unified Visual Encoding and Decoding from Neural Activity](https://mlsanity.com/paper/2604.09817/) (2026)
- [MIRAGE: Robust multi-modal architectures translate fMRI-to-image models from vision to mental imagery](https://mlsanity.com/paper/2605.17198/) (2026)
- [Brain-IT-VQA: From Brain Signals to Answers](https://mlsanity.com/paper/2605.29588/) (2026)

## Abstract (arXiv)

Every day, the human brain processes an immense volume of visual information, relying on intricate neural mechanisms to perceive and interpret these stimuli. Recent breakthroughs in functional magnetic resonance imaging (fMRI) have enabled scientists to extract visual information from human brain activity patterns. In this study, we present an innovative method for decoding brain activity into meaningful images and captions, with a specific focus on brain captioning due to its enhanced flexibility as compared to brain decoding into images. Our approach takes advantage of cutting-edge image captioning models and incorporates a unique image reconstruction pipeline that utilizes latent diffusion models and depth estimation. We utilized the Natural Scenes Dataset, a comprehensive fMRI dataset from eight subjects who viewed images from the COCO dataset. We employed the Generative Image-to-text Transformer (GIT) as our backbone for captioning and propose a new image reconstruction pipeline based on latent diffusion models. The method involves training regularized linear regression models between brain activity and extracted features. Additionally, we incorporated depth maps from the ControlNet model to further guide the reconstruction process. We evaluate our methods using quantitative metrics for both generated captions and images. Our brain captioning approach outperforms existing methods, while our image reconstruction pipeline generates plausible images with improved spatial relationships. In conclusion, we demonstrate significant progress in brain decoding, showcasing the enormous potential of integrating vision and language to better understand human cognition. Our approach provides a flexible platform for future research, with potential applications in various fields, including neural art, style transfer, and portable devices.