# Skeleton Graph-based Ultrasound-CT Non-rigid Registration

arXiv: https://arxiv.org/abs/2305.08228 · HTML: https://mlsanity.com/paper/2305.08228/

## Key facts

- Cited by 9 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 44 references that are in the map.
- First posted on arXiv 14 May 2023.

## Builds on (most cited first, 8 of 8)

- [Towards MRI-Based Autonomous Robotic US Acquisitions: A First Feasibility Study](https://mlsanity.com/paper/1607.08371/) (2016)
- [Autonomous Robotic Screening of Tubular Structures based only on Real-Time Ultrasound Imaging Feedback](https://mlsanity.com/paper/2011.00099/) (2020)
- [Deformation-Aware Robotic 3D Ultrasound](https://mlsanity.com/paper/2107.08411/) (2021)
- [Towards Autonomous Atlas-based Ultrasound Acquisitions in Presence of Articulated Motion](https://mlsanity.com/paper/2208.05399/) (2022)
- [Motion-Aware Robotic 3D Ultrasound](https://mlsanity.com/paper/2107.05998/) (2021)
- [Precise Repositioning of Robotic Ultrasound: Improving Registration-based Motion Compensation using Ultrasound Confidence Optimization](https://mlsanity.com/paper/2208.05383/) (2022)
- [Model-Based Compensation of Moving Tissue for State Recognition in Robotic-Assisted Pedicle Drilling](https://mlsanity.com/paper/2006.01650/) (2020)
- [Enabling Augmented Segmentation and Registration in Ultrasound-Guided Spinal Surgery via Realistic Ultrasound Synthesis from Diagnostic CT Volume](https://mlsanity.com/paper/2301.01940/) (2023)

## Built on by (most cited first, 9 of 9)

- [From Screens to Scenes: A Survey of Embodied AI in Healthcare](https://mlsanity.com/paper/2501.07468/) (2025)
- [DefCor-Net: Physics-Aware Ultrasound Deformation Correction](https://mlsanity.com/paper/2308.03865/) (2023)
- [Class-Aware Cartilage Segmentation for Autonomous US-CT Registration in Robotic Intercostal Ultrasound Imaging](https://mlsanity.com/paper/2406.04100/) (2024)
- [Thoracic Cartilage Ultrasound-CT Registration using Dense Skeleton Graph](https://mlsanity.com/paper/2307.03800/) (2023)
- [Autonomous Path Planning for Intercostal Robotic Ultrasound Imaging Using Reinforcement Learning](https://mlsanity.com/paper/2404.09927/) (2024)
- [SAMe: A Semantic Anatomy Mapping Engine for Robotic Ultrasound](https://mlsanity.com/paper/2604.25646/) (2026)
- [Point-Wise Geometry-Aware Transformer for Partial-to-Full Point Cloud Registration in Computer-Assisted Surgery](https://mlsanity.com/paper/2606.13488/) (2026)
- [Scanning While Imagining: A Scene-Graph World Model for Robotic Ultrasound Navigation](https://mlsanity.com/paper/2609.32837/) (2026)
- [Mask2Restore: Self-Supervised Ultrasound Despeckling via Inpainting](https://mlsanity.com/paper/2609.32844/) (2026)

## Abstract (arXiv)

Autonomous ultrasound (US) scanning has attracted increased attention, and it has been seen as a potential solution to overcome the limitations of conventional US examinations, such as inter-operator variations. However, it is still challenging to autonomously and accurately transfer a planned scan trajectory on a generic atlas to the current setup for different patients, particularly for thorax applications with limited acoustic windows. To address this challenge, we proposed a skeleton graph-based non-rigid registration to adapt patient-specific properties using subcutaneous bone surface features rather than the skin surface. To this end, the self-organization mapping is successively used twice to unify the input point cloud and extract the key points, respectively. Afterward, the minimal spanning tree is employed to generate a tree graph to connect all extracted key points. To appropriately characterize the rib cartilage outline to match the source and target point cloud, the path extracted from the tree graph is optimized by maximally maintaining continuity throughout each rib. To validate the proposed approach, we manually extract the US cartilage point cloud from one volunteer and seven CT cartilage point clouds from different patients. The results demonstrate that the proposed graph-based registration is more effective and robust in adapting to the inter-patient variations than the ICP (distance error mean/SD: 5.0/1.9 mm vs 8.6/6.7 mm on seven CTs).
