# Reconstructing seen images from human brain activity via guided stochastic search

arXiv: https://arxiv.org/abs/2305.00556 · HTML: https://mlsanity.com/paper/2305.00556/

## Key facts

- Cited by 8 papers in the map (data through 14 Oct 2026).
- Placed in Medical imaging and segmentation, one of 14 directions in Diffusion models.
- Builds on 5 of its 13 references that are in the map.
- First posted on arXiv 30 Apr 2023.

## Placed in

- Diffusion models / [Medical imaging and segmentation](https://mlsanity.com/diffusion/medical-imaging-and-segmentation/)

## Builds on (most cited first, 5 of 5)

- [Learning Transferable Visual Models From Natural Language Supervision](https://mlsanity.com/paper/2103.00020/) (2021)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Microsoft COCO: Common Objects in Context](https://mlsanity.com/paper/1405.0312/) (2014)
- [Mind Reader: Reconstructing complex images from brain activities](https://mlsanity.com/paper/2210.01769/) (2022)
- [Decoding natural image stimuli from fMRI data with a surface-based convolutional network](https://mlsanity.com/paper/2212.02409/) (2022)

## Built on by (most cited first, 8 of 8)

- [MindEye2: Shared-Subject Models Enable fMRI-To-Image With 1 Hour of Data](https://mlsanity.com/paper/2403.11207/) (2024)
- [Brain-optimized inference improves reconstructions of fMRI brain activity](https://mlsanity.com/paper/2312.07705/) (2023)
- [NSD-Imagery: A benchmark dataset for extending fMRI vision decoding methods to mental imagery](https://mlsanity.com/paper/2506.06898/) (2025)
- [Dynadiff: Single-stage Decoding of Images from Continuously Evolving fMRI](https://mlsanity.com/paper/2505.14556/) (2025)
- [TROI: Cross-Subject Pretraining with Sparse Voxel Selection for Enhanced fMRI Visual Decoding](https://mlsanity.com/paper/2502.00412/) (2025)
- [ENIGMA: EEG-to-Image in 15 Minutes Using Less Than 1% of the Parameters](https://mlsanity.com/paper/2602.10361/) (2026)
- [Brain3D: EEG-to-3D Decoding of Visual Representations via Multimodal Reasoning](https://mlsanity.com/paper/2604.08068/) (2026)
- [MIRAGE: Robust multi-modal architectures translate fMRI-to-image models from vision to mental imagery](https://mlsanity.com/paper/2605.17198/) (2026)

## Abstract (arXiv)

Visual reconstruction algorithms are an interpretive tool that map brain activity to pixels. Past reconstruction algorithms employed brute-force search through a massive library to select candidate images that, when passed through an encoding model, accurately predict brain activity. Here, we use conditional generative diffusion models to extend and improve this search-based strategy. We decode a semantic descriptor from human brain activity (7T fMRI) in voxels across most of visual cortex, then use a diffusion model to sample a small library of images conditioned on this descriptor. We pass each sample through an encoding model, select the images that best predict brain activity, and then use these images to seed another library. We show that this process converges on high-quality reconstructions by refining low-level image details while preserving semantic content across iterations. Interestingly, the time-to-convergence differs systematically across visual cortex, suggesting a succinct new way to measure the diversity of representations across visual brain areas.