# A marker-less human motion analysis system for motion-based biomarker discovery in knee disorders

arXiv: https://arxiv.org/abs/2304.13678 · HTML: https://mlsanity.com/paper/2304.13678/

## Key facts

- No citing papers in the map yet (data through 14 Oct 2026).
- Builds on 9 of its 53 references that are in the map.
- First posted on arXiv 26 Apr 2023.

## Builds on (most cited first, 9 of 9)

- [Expressive Body Capture: 3D Hands, Face, and Body from a Single Image](https://mlsanity.com/paper/1904.05866/) (2019)
- [AMASS: Archive of Motion Capture as Surface Shapes](https://mlsanity.com/paper/1904.03278/) (2019)
- [OpenPose: Realtime Multi-Person 2D Pose Estimation using Part Affinity Fields](https://mlsanity.com/paper/1812.08008/) (2018)
- [Realtime Multi-Person 2D Pose Estimation using Part Affinity Fields](https://mlsanity.com/paper/1611.08050/) (2016)
- [VIBE: Video Inference for Human Body Pose and Shape Estimation](https://mlsanity.com/paper/1912.05656/) (2019)
- [Monocular 3D Human Pose Estimation In The Wild Using Improved CNN Supervision](https://mlsanity.com/paper/1611.09813/) (2016)
- [Learning 3D Human Dynamics from Video](https://mlsanity.com/paper/1812.01601/) (2018)
- [Beyond Static Features for Temporally Consistent 3D Human Pose and Shape from a Video](https://mlsanity.com/paper/2011.08627/) (2020)
- [Cross View Fusion for 3D Human Pose Estimation](https://mlsanity.com/paper/1909.01203/) (2019)

## Abstract (arXiv)

In recent years the NHS has been having increased difficulty seeing all low-risk patients, this includes but not limited to suspected osteoarthritis (OA) patients. To help address the increased waiting lists and shortages of staff, we propose a novel method of automated biomarker identification for diagnosis of knee disorders and the monitoring of treatment progression. The proposed method allows for the measurement and analysis of biomechanics and analyse their clinical significance, in both a cheap and sensitive alternative to the currently available commercial alternatives. These methods and results validate the capabilities of standard RGB cameras in clinical environments to capture motion and show that when compared to alternatives such as depth cameras there is a comparable accuracy in the clinical environment. Biomarker identification using Principal Component Analysis (PCA) allows the reduction of the dimensionality to produce the most representative features from motion data, these new biomarkers can then be used to assess the success of treatment and track the progress of rehabilitation. This was validated by applying these techniques on a case study utilising the exploratory use of local anaesthetic applied on knee pain, this allows these new representative biomarkers to be validated as statistically significant (p-value < 0.05).