# Score-Based Diffusion Models as Principled Priors for Inverse Imaging

arXiv: https://arxiv.org/abs/2304.11751 · HTML: https://mlsanity.com/paper/2304.11751/

## Key facts

- Cited by 127 papers in the map (data through 14 Oct 2026).
- Placed in Inverse problems and image restoration, one of 14 directions in Diffusion models.
- Builds on 58 of its 89 references that are in the map.
- First posted on arXiv 23 Apr 2023.

## Placed in

- Diffusion models / [Inverse problems and image restoration](https://mlsanity.com/diffusion/inverse-problems-and-image-restoration/)

## Builds on (most cited first, 30 of 58)

- [Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2006.11239/) (2020)
- [High-Resolution Image Synthesis with Latent Diffusion Models](https://mlsanity.com/paper/2112.10752/) (2021)
- [Denoising Diffusion Implicit Models](https://mlsanity.com/paper/2010.02502/) (2020)
- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Diffusion Models Beat GANs on Image Synthesis](https://mlsanity.com/paper/2105.05233/) (2021)
- [Deep Unsupervised Learning using Nonequilibrium Thermodynamics](https://mlsanity.com/paper/1503.03585/) (2015)
- [Hierarchical Text-Conditional Image Generation with CLIP Latents](https://mlsanity.com/paper/2204.06125/) (2022)
- [Photorealistic Text-to-Image Diffusion Models with Deep Language Understanding](https://mlsanity.com/paper/2205.11487/) (2022)
- [Classifier-Free Diffusion Guidance](https://mlsanity.com/paper/2207.12598/) (2022)
- [Generative Adversarial Networks](https://mlsanity.com/paper/2203.00667/) (2022)
- [Generative Modeling by Estimating Gradients of the Data Distribution](https://mlsanity.com/paper/1907.05600/) (2019)
- [Auto-Encoding Variational Bayes](https://mlsanity.com/paper/1312.6114/) (2013)
- [Neural Ordinary Differential Equations](https://mlsanity.com/paper/1806.07366/) (2018)
- [Improved Denoising Diffusion Probabilistic Models](https://mlsanity.com/paper/2102.09672/) (2021)
- [Deep Learning Face Attributes in the Wild](https://mlsanity.com/paper/1411.7766/) (2014)
- [GLIDE: Towards Photorealistic Image Generation and Editing with Text-Guided Diffusion Models](https://mlsanity.com/paper/2112.10741/) (2021)
- [Density estimation using Real NVP](https://mlsanity.com/paper/1605.08803/) (2016)
- [Glow: Generative Flow with Invertible 1x1 Convolutions](https://mlsanity.com/paper/1807.03039/) (2018)
- [Image Super-Resolution via Iterative Refinement](https://mlsanity.com/paper/2104.07636/) (2021)
- [Variational Inference: A Review for Statisticians](https://mlsanity.com/paper/1601.00670/) (2016)
- [Context Encoders: Feature Learning by Inpainting](https://mlsanity.com/paper/1604.07379/) (2016)
- [Diffusion Posterior Sampling for General Noisy Inverse Problems](https://mlsanity.com/paper/2209.14687/) (2022)
- [Cascaded Diffusion Models for High Fidelity Image Generation](https://mlsanity.com/paper/2106.15282/) (2021)
- [Variational Diffusion Models](https://mlsanity.com/paper/2107.00630/) (2021)
- [Deep Image Prior](https://mlsanity.com/paper/1711.10925/) (2017)
- [NICE: Non-linear Independent Components Estimation](https://mlsanity.com/paper/1410.8516/) (2014)
- [Denoising Diffusion Restoration Models](https://mlsanity.com/paper/2201.11793/) (2022)
- [Pixel Recurrent Neural Networks](https://mlsanity.com/paper/1601.06759/) (2016)
- [Masked Autoregressive Flow for Density Estimation](https://mlsanity.com/paper/1705.07057/) (2017)
- [Maximum Likelihood Training of Score-Based Diffusion Models](https://mlsanity.com/paper/2101.09258/) (2021)

## Built on by (most cited first, 30 of 127)

- [A Survey on Diffusion Models for Inverse Problems](https://mlsanity.com/paper/2410.00083/) (2024)
- [Improving Diffusion Inverse Problem Solving with Decoupled Noise Annealing](https://mlsanity.com/paper/2407.01521/) (2024)
- [Diffusion Models for Image Restoration and Enhancement: A Comprehensive Survey](https://mlsanity.com/paper/2308.09388/) (2023)
- [Principled Probabilistic Imaging using Diffusion Models as Plug-and-Play Priors](https://mlsanity.com/paper/2405.18782/) (2024)
- [Provably Robust Score-Based Diffusion Posterior Sampling for Plug-and-Play Image Reconstruction](https://mlsanity.com/paper/2403.17042/) (2024)
- [Amortizing intractable inference in diffusion models for vision, language, and control](https://mlsanity.com/paper/2405.20971/) (2024)
- [Prompt-tuning latent diffusion models for inverse problems](https://mlsanity.com/paper/2310.01110/) (2023)
- [InverseBench: Benchmarking Plug-and-Play Diffusion Priors for Inverse Problems in Physical Sciences](https://mlsanity.com/paper/2503.11043/) (2025)
- [Estimating Epistemic and Aleatoric Uncertainty with a Single Model](https://mlsanity.com/paper/2402.03478/) (2024)
- [Flow Priors for Linear Inverse Problems via Iterative Corrupted Trajectory Matching](https://mlsanity.com/paper/2405.18816/) (2024)
- [Provable Probabilistic Imaging using Score-Based Generative Priors](https://mlsanity.com/paper/2310.10835/) (2023)
- [Improving Diffusion Models for Inverse Problems Using Optimal Posterior Covariance](https://mlsanity.com/paper/2402.02149/) (2024)
- [CG3D: Compositional Generation for Text-to-3D via Gaussian Splatting](https://mlsanity.com/paper/2311.17907/) (2023)
- [Neural Network Diffusion](https://mlsanity.com/paper/2402.13144/) (2024)
- [Image Restoration Through Generalized Ornstein-Uhlenbeck Bridge](https://mlsanity.com/paper/2312.10299/) (2023)
- [Denoising: A Powerful Building-Block for Imaging, Inverse Problems, and Machine Learning](https://mlsanity.com/paper/2409.06219/) (2024)
- [Ambient Diffusion Posterior Sampling: Solving Inverse Problems with Diffusion Models Trained on Corrupted Data](https://mlsanity.com/paper/2403.08728/) (2024)
- [Does FLUX Already Know How to Perform Physically Plausible Image Composition?](https://mlsanity.com/paper/2509.21278/) (2025)
- [What's in a Prior? Learned Proximal Networks for Inverse Problems](https://mlsanity.com/paper/2310.14344/) (2023)
- [Generative Plug and Play: Posterior Sampling for Inverse Problems](https://mlsanity.com/paper/2306.07233/) (2023)
- [Towards Real-World Blind Face Restoration with Generative Diffusion Prior](https://mlsanity.com/paper/2312.15736/) (2023)
- [Rethinking Diffusion Posterior Sampling: From Conditional Score Estimator to Maximizing a Posterior](https://mlsanity.com/paper/2501.18913/) (2025)
- [Deep Diffusion Image Prior for Efficient OOD Adaptation in 3D Inverse Problems](https://mlsanity.com/paper/2407.10641/) (2024)
- [An Expectation-Maximization Algorithm for Training Clean Diffusion Models from Corrupted Observations](https://mlsanity.com/paper/2407.01014/) (2024)
- [UniDB: A Unified Diffusion Bridge Framework via Stochastic Optimal Control](https://mlsanity.com/paper/2502.05749/) (2025)
- [Split Gibbs Discrete Diffusion Posterior Sampling](https://mlsanity.com/paper/2503.01161/) (2025)
- [Dehazing Ultrasound using Diffusion Models](https://mlsanity.com/paper/2307.11204/) (2023)
- [Variational Bayesian Imaging with an Efficient Surrogate Score-based Prior](https://mlsanity.com/paper/2309.01949/) (2023)
- [Uncertainty Quantification via Neural Posterior Principal Components](https://mlsanity.com/paper/2309.15533/) (2023)
- [Conditional LoRA Parameter Generation](https://mlsanity.com/paper/2408.01415/) (2024)

## Abstract (arXiv)

Priors are essential for reconstructing images from noisy and/or incomplete measurements. The choice of the prior determines both the quality and uncertainty of recovered images. We propose turning score-based diffusion models into principled image priors ("score-based priors") for analyzing a posterior of images given measurements. Previously, probabilistic priors were limited to handcrafted regularizers and simple distributions. In this work, we empirically validate the theoretically-proven probability function of a score-based diffusion model. We show how to sample from resulting posteriors by using this probability function for variational inference. Our results, including experiments on denoising, deblurring, and interferometric imaging, suggest that score-based priors enable principled inference with a sophisticated, data-driven image prior.