# Weakly Unsupervised Domain Adaptation for Vestibular Schwannoma Segmentation

arXiv: https://arxiv.org/abs/2303.07093 · HTML: https://mlsanity.com/paper/2303.07093/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 8 of its 12 references that are in the map.
- First posted on arXiv 13 Mar 2023.

## Builds on (most cited first, 8 of 8)

- [Analyzing and Improving the Image Quality of StyleGAN](https://mlsanity.com/paper/1912.04958/) (2019)
- [Contrastive Learning for Unpaired Image-to-Image Translation](https://mlsanity.com/paper/2007.15651/) (2020)
- [CrossMoDA 2021 challenge: Benchmark of Cross-Modality Domain Adaptation techniques for Vestibular Schwannoma and Cochlea Segmentation](https://mlsanity.com/paper/2201.02831/) (2022)
- [Scribble-based Domain Adaptation via Co-segmentation](https://mlsanity.com/paper/2007.03632/) (2020)
- [Squeeze-and-Excitation Normalization for Automated Delineation of Head and Neck Primary Tumors in Combined PET and CT Images](https://mlsanity.com/paper/2102.10446/) (2021)
- [Unsupervised Domain Adaptation in Semantic Segmentation Based on Pixel Alignment and Self-Training](https://mlsanity.com/paper/2109.14219/) (2021)
- [Using Out-of-the-Box Frameworks for Contrastive Unpaired Image Translation for Vestibular Schwannoma and Cochlea Segmentation: An approach for the crossMoDA Challenge](https://mlsanity.com/paper/2110.01607/) (2021)
- [Self-Training Based Unsupervised Cross-Modality Domain Adaptation for Vestibular Schwannoma and Cochlea Segmentation](https://mlsanity.com/paper/2109.10674/) (2021)

## Built on by (most cited first, 1 of 1)

- [crossMoDA Challenge: Evolution of Cross-Modality Domain Adaptation Techniques for Vestibular Schwannoma and Cochlea Segmentation from 2021 to 2023](https://mlsanity.com/paper/2506.12006/) (2025)

## Abstract (arXiv)

Vestibular schwannoma (VS) is a non-cancerous tumor located next to the ear that can cause hearing loss. Most brain MRI images acquired from patients are contrast-enhanced T1 (ceT1), with a growing interest in high-resolution T2 images (hrT2) to replace ceT1, which involves the use of a contrast agent. As hrT2 images are currently scarce, it is less likely to train robust machine learning models to segment VS or other brain structures. In this work, we propose a weakly supervised machine learning approach that learns from only ceT1 scans and adapts to segment two structures from hrT2 scans: the VS and the cochlea from the crossMoDA dataset. Our model 1) generates fake hrT2 scans from ceT1 images and segmentation masks, 2) is trained using the fake hrT2 scans, 3) predicts the augmented real hrT2 scans, and 4) is retrained again using both the fake and real hrT2. The final result of this model has been computed on an unseen testing dataset provided by the 2022 crossMoDA challenge organizers. The mean dice score and average symmetric surface distance (ASSD) are 0.78 and 0.46, respectively. The predicted segmentation masks achieved a dice score of 0.83 and an ASSD of 0.56 on the VS, and a dice score of 0.74 and an ASSD of 0.35 on the cochleas.