# Region and Spatial Aware Anomaly Detection for Fundus Images

arXiv: https://arxiv.org/abs/2303.03817 · HTML: https://mlsanity.com/paper/2303.03817/

## Key facts

- Cited by 1 papers in the map (data through 14 Oct 2026).
- Builds on 10 of its 19 references that are in the map.
- First posted on arXiv 7 Mar 2023.

## Builds on (most cited first, 10 of 10)

- [Wide Residual Networks](https://mlsanity.com/paper/1605.07146/) (2016)
- [Towards Total Recall in Industrial Anomaly Detection](https://mlsanity.com/paper/2106.08265/) (2021)
- [Unsupervised Anomaly Detection with Generative Adversarial Networks to Guide Marker Discovery](https://mlsanity.com/paper/1703.05921/) (2017)
- [Memorizing Normality to Detect Anomaly: Memory-augmented Deep Autoencoder for Unsupervised Anomaly Detection](https://mlsanity.com/paper/1904.02639/) (2019)
- [Multiresolution Knowledge Distillation for Anomaly Detection](https://mlsanity.com/paper/2011.11108/) (2020)
- [Deep Autoencoding Models for Unsupervised Anomaly Segmentation in Brain MR Images](https://mlsanity.com/paper/1804.04488/) (2018)
- [ADAM Challenge: Detecting Age-related Macular Degeneration from Fundus Images](https://mlsanity.com/paper/2202.07983/) (2022)
- [Proxy-bridged Image Reconstruction Network for Anomaly Detection in Medical Images](https://mlsanity.com/paper/2110.01761/) (2021)
- [Dual-Distribution Discrepancy for Anomaly Detection in Chest X-Rays](https://mlsanity.com/paper/2206.03935/) (2022)
- [Anomaly Detection in Retinal Images using Multi-Scale Deep Feature Sparse Coding](https://mlsanity.com/paper/2201.11506/) (2022)

## Built on by (most cited first, 1 of 1)

- [ReSynthDetect: A Fundus Anomaly Detection Network with Reconstruction and Synthetic Features](https://mlsanity.com/paper/2312.16470/) (2023)

## Abstract (arXiv)

Recently anomaly detection has drawn much attention in diagnosing ocular diseases. Most existing anomaly detection research in fundus images has relatively large anomaly scores in the salient retinal structures, such as blood vessels, optical cups and discs. In this paper, we propose a Region and Spatial Aware Anomaly Detection (ReSAD) method for fundus images, which obtains local region and long-range spatial information to reduce the false positives in the normal structure. ReSAD transfers a pre-trained model to extract the features of normal fundus images and applies the Region-and-Spatial-Aware feature Combination module (ReSC) for pixel-level features to build a memory bank. In the testing phase, ReSAD uses the memory bank to determine out-of-distribution samples as abnormalities. Our method significantly outperforms the existing anomaly detection methods for fundus images on two publicly benchmark datasets.