# Deep Momentum Multi-Marginal Schr"odinger Bridge

arXiv: https://arxiv.org/abs/2303.01751 · HTML: https://mlsanity.com/paper/2303.01751/

## Key facts

- Cited by 42 papers in the map (data through 14 Oct 2026).
- Builds on 23 of its 59 references that are in the map.
- First posted on arXiv 3 Mar 2023.

## Builds on (most cited first, 23 of 23)

- [Score-Based Generative Modeling through Stochastic Differential Equations](https://mlsanity.com/paper/2011.13456/) (2020)
- [Neural Ordinary Differential Equations](https://mlsanity.com/paper/1806.07366/) (2018)
- [Maximum Likelihood Training of Score-Based Diffusion Models](https://mlsanity.com/paper/2101.09258/) (2021)
- [Diffusion Schr"odinger Bridge with Applications to Score-Based Generative Modeling](https://mlsanity.com/paper/2106.01357/) (2021)
- [Score-Based Generative Modeling with Critically-Damped Langevin Diffusion](https://mlsanity.com/paper/2112.07068/) (2021)
- [Likelihood Training of Schr"odinger Bridge using Forward-Backward SDEs Theory](https://mlsanity.com/paper/2110.11291/) (2021)
- [TrajectoryNet: A Dynamic Optimal Transport Network for Modeling Cellular Dynamics](https://mlsanity.com/paper/2002.04461/) (2020)
- [Solving Schr"odinger Bridges via Maximum Likelihood](https://mlsanity.com/paper/2106.02081/) (2021)
- [Regularizing Generative Adversarial Networks under Limited Data](https://mlsanity.com/paper/2104.03310/) (2021)
- [Proximal Optimal Transport Modeling of Population Dynamics](https://mlsanity.com/paper/2106.06345/) (2021)
- [Manifold Interpolating Optimal-Transport Flows for Trajectory Inference](https://mlsanity.com/paper/2206.14928/) (2022)
- [Conditional Simulation Using Diffusion Schr"odinger Bridges](https://mlsanity.com/paper/2202.13460/) (2022)
- [Wasserstein Proximal Algorithms for the Schr"odinger Bridge Problem: Density Control with Nonlinear Drift](https://mlsanity.com/paper/1912.01244/) (2019)
- [Scalable Unbalanced Optimal Transport using Generative Adversarial Networks](https://mlsanity.com/paper/1810.11447/) (2018)
- [Trajectory Inference via Mean-field Langevin in Path Space](https://mlsanity.com/paper/2205.07146/) (2022)
- [Second order models for optimal transport and cubic splines on the Wasserstein space](https://mlsanity.com/paper/1801.04144/) (2018)
- [Measure-valued spline curves: an optimal transport viewpoint](https://mlsanity.com/paper/1801.03186/) (2018)
- [The most likely evolution of diffusing and vanishing particles: Schrodinger Bridges with unbalanced marginals](https://mlsanity.com/paper/2108.02879/) (2021)
- [Learning Optimal Control via Forward and Backward Stochastic Differential Equations](https://mlsanity.com/paper/1509.02195/) (2015)
- [Applying Regularized Schr"odinger-Bridge-Based Stochastic Process in Generative Modeling](https://mlsanity.com/paper/2208.07131/) (2022)
- [Multi-marginal Schrodinger bridges](https://mlsanity.com/paper/1902.08319/) (2019)
- [Large-Scale Multi-Agent Deep FBSDEs](https://mlsanity.com/paper/2011.10890/) (2020)
- [Deep Graphic FBSDEs for Opinion Dynamics Stochastic Control](https://mlsanity.com/paper/2204.02506/) (2022)

## Built on by (most cited first, 30 of 42)

- [Diffusion Schr"odinger Bridge Matching](https://mlsanity.com/paper/2303.16852/) (2023)
- [A Computational Framework for Solving Wasserstein Lagrangian Flows](https://mlsanity.com/paper/2310.10649/) (2023)
- [Multi-marginal Schr"odinger Bridges with Iterative Reference Refinement](https://mlsanity.com/paper/2408.06277/) (2024)
- [Generative Modeling with Phase Stochastic Bridges](https://mlsanity.com/paper/2310.07805/) (2023)
- [Learning diffusion at lightspeed](https://mlsanity.com/paper/2406.12616/) (2024)
- [Joint Velocity-Growth Flow Matching for Single-Cell Dynamics Modeling](https://mlsanity.com/paper/2505.13413/) (2025)
- [Trivialized Momentum Facilitates Diffusion Generative Modeling on Lie Groups](https://mlsanity.com/paper/2405.16381/) (2024)
- [Generative modeling for time series via Schr"odinger bridge](https://mlsanity.com/paper/2304.05093/) (2023)
- [GLASS Flows: Transition Sampling for Alignment of Flow and Diffusion Models](https://mlsanity.com/paper/2509.25170/) (2025)
- [Tree-Based Diffusion Schr"odinger Bridge with Applications to Wasserstein Barycenters](https://mlsanity.com/paper/2305.16557/) (2023)
- [Trajectory Inference with Smooth Schr"odinger Bridges](https://mlsanity.com/paper/2503.00530/) (2025)
- [Momentum Multi-Marginal Schr"odinger Bridge Matching](https://mlsanity.com/paper/2506.10168/) (2025)
- [Multi-Marginal Stochastic Flow Matching for High-Dimensional Snapshot Data at Irregular Time Points](https://mlsanity.com/paper/2508.04351/) (2025)
- [Diffusion & Adversarial Schr"odinger Bridges via Iterative Proportional Markovian Fitting](https://mlsanity.com/paper/2410.02601/) (2024)
- [Learning of Population Dynamics: Inverse Optimization Meets JKO Scheme](https://mlsanity.com/paper/2506.01502/) (2025)
- [Quantum State Generation with Structure-Preserving Diffusion Model](https://mlsanity.com/paper/2404.06336/) (2024)
- [DICE: Discrete inverse continuity equation for learning population dynamics](https://mlsanity.com/paper/2507.05107/) (2025)
- [Oh SnapMMD! Forecasting Stochastic Dynamics Beyond the Schr"odinger Bridge's End](https://mlsanity.com/paper/2505.16082/) (2025)
- [Branched Schr"odinger Bridge Matching](https://mlsanity.com/paper/2506.09007/) (2025)
- [Functional Adjoint Sampler: Scalable Sampling on Infinite Dimensional Spaces](https://mlsanity.com/paper/2511.06239/) (2025)
- [Efficient Generative Modeling beyond Memoryless Diffusion via Adjoint Schr"odinger Bridge Matching](https://mlsanity.com/paper/2602.15396/) (2026)
- [Correlational Lagrangian Schr"odinger Bridge: Learning Dynamics with Population-Level Regularization](https://mlsanity.com/paper/2402.10227/) (2024)
- [Optimal Stochastic Trace Estimation in Generative Modeling](https://mlsanity.com/paper/2502.18808/) (2025)
- [Schr"odinger Bridge Matching for Tree-Structured Costs and Entropic Wasserstein Barycentres](https://mlsanity.com/paper/2506.17197/) (2025)
- [TADA: Improved Diffusion Sampling with Training-free Augmented Dynamics](https://mlsanity.com/paper/2506.21757/) (2025)
- [Flows and Diffusions on the Neural Manifold](https://mlsanity.com/paper/2507.10623/) (2025)
- [Optimal Multimarginal Schr"odinger Bridge: Minimum Spanning Tree over Measure-valued Vertices](https://mlsanity.com/paper/2509.10626/) (2025)
- [Relative Entropy Estimation in Function Space: Theory and Applications to Trajectory Inference](https://mlsanity.com/paper/2604.20775/) (2026)
- [ABC: Any-Subset Autoregression via Non-Markovian Diffusion Bridges in Continuous Time and Space](https://mlsanity.com/paper/2604.27443/) (2026)
- [PACE: Geometry-Aware Bridge Transport for Single-Cell Trajectory Inference](https://mlsanity.com/paper/2605.18587/) (2026)

## Abstract (arXiv)

It is a crucial challenge to reconstruct population dynamics using unlabeled samples from distributions at coarse time intervals. Recent approaches such as flow-based models or Schr"odinger Bridge (SB) models have demonstrated appealing performance, yet the inferred sample trajectories either fail to account for the underlying stochasticity or are underlineDeep underlineMomentum Multi-Marginal underlineSchr"odinger underlineBridge(DMSB), a novel computational framework that learns the smooth measure-valued spline for stochastic systems that satisfy position marginal constraints across time. By tailoring the celebrated Bregman Iteration and extending the Iteration Proportional Fitting to phase space, we manage to handle high-dimensional multi-marginal trajectory inference tasks efficiently. Our algorithm outperforms baselines significantly, as evidenced by experiments for synthetic datasets and a real-world single-cell RNA sequence dataset. Additionally, the proposed approach can reasonably reconstruct the evolution of velocity distribution, from position snapshots only, when there is a ground truth velocity that is nevertheless inaccessible.
