# RECIST Weakly Supervised Lesion Segmentation via Label-Space Co-Training

arXiv: https://arxiv.org/abs/2303.00205 · HTML: https://mlsanity.com/paper/2303.00205/

## Key facts

- Cited by 2 papers in the map (data through 14 Oct 2026).
- Builds on 19 of its 28 references that are in the map.
- First posted on arXiv 1 Mar 2023.

## Builds on (most cited first, 19 of 19)

- [Adam: A Method for Stochastic Optimization](https://mlsanity.com/paper/1412.6980/) (2014)
- [PyTorch: An Imperative Style, High-Performance Deep Learning Library](https://mlsanity.com/paper/1912.01703/) (2019)
- [U-Net: Convolutional Networks for Biomedical Image Segmentation](https://mlsanity.com/paper/1505.04597/) (2015)
- [Swin Transformer: Hierarchical Vision Transformer using Shifted Windows](https://mlsanity.com/paper/2103.14030/) (2021)
- [Momentum Contrast for Unsupervised Visual Representation Learning](https://mlsanity.com/paper/1911.05722/) (2019)
- [V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentation](https://mlsanity.com/paper/1606.04797/) (2016)
- [ScribbleSup: Scribble-Supervised Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1604.05144/) (2016)
- [BoxSup: Exploiting Bounding Boxes to Supervise Convolutional Networks for Semantic Segmentation](https://mlsanity.com/paper/1503.01640/) (2015)
- [Semi-supervised Medical Image Segmentation through Dual-task Consistency](https://mlsanity.com/paper/2009.04448/) (2020)
- [The KiTS19 Challenge Data: 300 Kidney Tumor Cases with Clinical Context, CT Semantic Segmentations, and Surgical Outcomes](https://mlsanity.com/paper/1904.00445/) (2019)
- [ACN: Adversarial Co-training Network for Brain Tumor Segmentation with Missing Modalities](https://mlsanity.com/paper/2106.14591/) (2021)
- [MULAN: Multitask Universal Lesion Analysis Network for Joint Lesion Detection, Tagging, and Segmentation](https://mlsanity.com/paper/1908.04373/) (2019)
- [Improving RetinaNet for CT Lesion Detection with Dense Masks from Weak RECIST Labels](https://mlsanity.com/paper/1906.02283/) (2019)
- [Accurate Weakly-Supervised Deep Lesion Segmentation using Large-Scale Clinical Annotations: Slice-Propagated 3D Mask Generation from 2D RECIST](https://mlsanity.com/paper/1807.01172/) (2018)
- [Weakly-Supervised Universal Lesion Segmentation with Regional Level Set Loss](https://mlsanity.com/paper/2105.01218/) (2021)
- [One Click Lesion RECIST Measurement and Segmentation on CT Scans](https://mlsanity.com/paper/2007.11087/) (2020)
- [Lesion Segmentation and RECIST Diameter Prediction via Click-driven Attention and Dual-path Connection](https://mlsanity.com/paper/2105.01828/) (2021)
- [Weakly-Supervised Lesion Segmentation on CT Scans using Co-Segmentation](https://mlsanity.com/paper/2001.08590/) (2020)
- [Conquering Data Variations in Resolution: A Slice-Aware Multi-Branch Decoder Network](https://mlsanity.com/paper/2203.03640/) (2022)

## Built on by (most cited first, 2 of 2)

- [Ultrasound Nodule Segmentation Using Asymmetric Learning with Simple Clinical Annotation](https://mlsanity.com/paper/2404.14852/) (2024)
- [SAM-Driven Weakly Supervised Nodule Segmentation with Uncertainty-Aware Cross Teaching](https://mlsanity.com/paper/2407.13553/) (2024)

## Abstract (arXiv)

As an essential indicator for cancer progression and treatment response, tumor size is often measured following the response evaluation criteria in solid tumors (RECIST) guideline in CT slices. By marking each lesion with its longest axis and the longest perpendicular one, laborious pixel-wise manual annotation can be avoided. However, such a coarse substitute cannot provide a rich and accurate base to allow versatile quantitative analysis of lesions. To this end, we propose a novel weakly supervised framework to exploit the existing rich RECIST annotations for pixel-wise lesion segmentation. Specifically, a pair of under- and over-segmenting masks are constructed for each lesion based on its RECIST annotation and served as the label for co-training a pair of subnets, respectively, along with the proposed label-space perturbation induced consistency loss to bridge the gap between the two subnets and enable effective co-training. Extensive experiments are conducted on a public dataset to demonstrate the superiority of the proposed framework regarding the RECIST-based weakly supervised segmentation task and its universal applicability to various backbone networks.